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Prognostic significance of cytokeratin 19 expression in pancreatic neuroendocrine tumor: A meta-analysis

Background Pancreatic neuroendocrine tumor (PNET) comprises 1–2% of all pancreatic tumors, but its incidence is increasing. Although many studies have investigated the correlation between cytokeratin 19 (CK-19) and PNET, the prognostic significance of CK-19 expression in PNET is inconclusive. Methods Eligible studies were retrieved from Pubmed, Elsevier, Embase, Cochrane Library ...

Perioperative risk factors for postoperative pneumonia after major oral cancer surgery: A retrospective analysis of 331 cases

Objective Postoperative pneumonia (POP) is common and results in prolonged hospital stays, higher costs, increased morbidity and mortality. However, data on the incidence and risk factors of POP after oral and maxillofacial surgery are rare. This study aims to identify perioperative risk factors for POP after major oral cancer (OC) surgery. Methods Perioperative data and patient ...

Comparative epidemiology of porcine circovirus type 3 in pigs with different clinical presentations

Porcine circovirus type 3 (PCV3), as an emerging circovirus species, was reported to be widely circulating in the United States, China, South Korea and Poland. Previous studies revealed that PCV3 was mainly concentrated in sick animals with respiratory disease, skin disease, reproductive disorders and so on. However, the circulating status of PCV3 in pigs with other clinical ...

Long-term retinal cone rescue using a capsid mutant AAV8 vector in a mouse model of CNGA3-achromatopsia

Adeno-associated virus (AAV) vectors are important gene delivery tools for the treatment of many recessively inherited retinal diseases. For example, a wild-type (WT) AAV5 vector can deliver a full-length Cnga3 (cyclic nucleotide-gated channel alpha-3) cDNA to target cells of the cone photoreceptor function loss 5 (cpfl5) mouse, a spontaneous animal model of achromatopsia with a ...

Impacts of the IOD-associated temperature and salinity anomalies on the intermittent equatorial undercurrent anomalies

The study of Equatorial Undercurrent (EUC) has attracted a broad attention in recent years due to its strong response and feedback to the Indian Ocean Dipole. In this paper, we first produce a high-quality simulation of three-dimensional temperature, salinity and zonal current simulation from 1982 to 2014, using a high-resolution ocean general circulation model. On this basis, with ...

Surgical management of spinal solitary fibrous tumor/hemangiopericytoma: a case series of 20 patients

Purpose Spinal solitary fibrous tumor/hemangiopericytoma (SFT/HPC), a rare mesenchymal tumor that arises from pericytes of Zimmerman, comprises only 0.08% of all primary bone tumors and 0.1% of primary malignant bone tumor and rarely occurs in the spine. We attempt to correlate the clinical factors and different treatment options with the recurrence rate and overall survival of ...

A regional case in the development of agriculture and crop processing in northern China from the Neolithic to Bronze Age: archaeobotanical evidence from the Sushui River survey, Shanxi province

The article presents the results of the analysis of survey archaeobotany samples from the Sushui valley. This provides evidence for changes over time for a region in the proportions of crops, especially rice versus millets. In addition, the composition of samples, both grouped by period and considered on a sample-by-sample basis, are considered as representing routine ...

Increase in 2.5 Micron Airborne Particulate Matters, AHPCO® and Plasma Nanotechnology in Reducing the Symptoms of Asthma and Allergic Rhinitis

Increase in the particulate matter of size 2.5 microns are a major health concern of the present decade that led to a gradual rise of allergy and asthma cases all over the world. When inhaled, they can reach deep into our lungs and enter tissues via the bloodstream and contribute to health conditions ranging from coughing or lung irritation to chronic bronchitis and cardiovascular ...

Cobalt-vanadium bimetal-based nanoplates for efficient overall water splitting

The development of effective and low-cost catalysts for overall water splitting is essential for clean production of hydrogen from water. In this paper, we report the synthesis of cobalt-vanadium (Co-V) bimetal-based catalysts for the effective water splitting. The Co2V2O7·xH2O nanoplates containing both Co and V elements were selected as the precursors. After the calcination under ...

Should the poor have no medicines to cure? A study on the association between social class and social security among the rural migrant workers in urban China

The rampant urbanization and medical marketization in China have resulted in increased vulnerabilities to health and socioeconomic disparities among the rural migrant workers in urban China. In the Chinese context, the socioeconomic characteristics of rural migrant workers have attracted considerable research attention in the recent past years. However, to date, no previous studies ...

Determining the target protein localization in 3D using the combination of FIB-SEM and APEX2

Determining the cellular localization of proteins of interest at nanometer resolution is necessary for elucidating their functions. Besides super-resolution fluorescence microscopy, conventional electron microscopy (EM) combined with immunolabeling or clonable EM tags provides a unique approach to correlate protein localization information and cellular ultrastructural information. ...

miR-324-3p promotes gastric cancer development by activating Smad4-mediated Wnt/beta-catenin signaling pathway

Background Emerging evidence suggested that miRNAs can function as oncogenes or tumor suppressors by regulating downstream target genes. miR-324-3p has been reported to function in several carcinomas, but its role in gastric cancer (GC) is still unknown. This study aims to explore the effects of miR-324-3p on the development of GC. Methods Expression of miR-324-3p was examined in ...

Tribological evaluation of environmentally friendly ionic liquids derived from renewable biomaterials

Unlike most of the conventional ionic liquids (ILs) derived from non-renewable resources, five environmentally friendly ILs ([Ch][AA] ILs) derived from amino acids (AAs) and choline (Ch) were synthesized using biomaterials by a simple, green route: acid–base reaction of Ch and AAs. The thermal and corrosion properties, as well as viscosity, of the prepared ILs were examined. The ...

Research on modulation recognition with ensemble learning

Modulation scheme recognition occupies a crucial position in the civil and military application. In this paper, we present boosting algorithm as an ensemble frame to achieve a higher accuracy than a single classifier. To evaluate the effect of boosting algorithm, eight common communication signals are yet to be identified. And five kinds of entropy are extracted as the training ...

Human umbilical cord-derived mesenchymal stem cells ameliorate insulin resistance by suppressing NLRP3 inflammasome-mediated inflammation in type 2 diabetes rats

Background Insulin resistance is one of the most common and important pathological features of type 2 diabetes (T2D). Recently, insulin resistance is increasingly considered to be associated with systemic chronic inflammation. Elevated levels of tumor necrosis factor (TNF)-α and interleukin (IL)-1β in blood are predictive indicators of the development of T2D. Mesenchymal stem cell ...

Preparation of graphene-MoS2 hybrid aerogels as multifunctional sorbents for water remediation

The increasing demand of clean water and effective way to recycle industrial wastewater has offered a new application for carbon-based three-dimensional (3D) porous networks as sorbents due to their superior sorption abilities. Through the surface modification and hybridization with functional materials, the physical and chemical properties of the 3D carbon-based materials can be ...

Effects of uric acid-lowering therapy in patients with chronic kidney disease: A meta-analysis

Background and objectives The effects of uric acid-lowering therapy in patients with chronic kidney disease (CKD) remain uncertain. Therefore, we undertook a systematic review and meta-analysis to investigate the effects of uric acid-lowering agents on major clinical outcomes of CKD. Design, setting, participants, and measurements According to the pre-specified protocol that was ...

Measurement of the triple-differential dijet cross section in proton-proton collisions at \(\sqrt{s}=8\,\text {TeV} \) and constraints on parton distribution functions

A measurement is presented of the triple-differential dijet cross section at a centre-of-mass energy of 8\(\,\text {TeV}\) using 19.7\(\,\text {fb}^\text {-1}\) of data collected with the CMS detector in proton-proton collisions at the LHC. The cross section is measured as a function of the average transverse momentum, half the rapidity separation, and the boost of the two leading ...