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Post-marketing surveillance study of the safety of dexamethasone intravitreal implant in patients with retinal vein occlusion or noninfectious posterior segment uveitis

Post-marketing surveillance study of the safety of dexamethasone intravitreal implant in patients with retinal vein occlusion or noninfectious posterior segment uveitis Adnan Tufail,1 Sue Lightman,1 Ahmed Kamal,2 Uwe Pleyer,3 Nuria María Gajate Paniagua,4 Corrine Dot,5,6 Xiao-Yan Li,7 Jenny Jiao,7 Jean Lou,7 Yehia Hashad7For the CONSTANCE Study Group1Moorfields Eye Hospital...

On the Boundedness Problem for Higher-Order Pushdown Vector Addition Systems

Karp and Miller's algorithm is a well-known decision procedure that solves the termination and boundedness problems for vector addition systems with states (VASS), or equivalently Petri nets. This procedure was later extended to a general class of models, well-structured transition systems, and, more recently, to pushdown VASS. In this paper, we extend pushdown VASS to higher...

Broken needle during spinal anesthesia: an avoidable complication

Broken needle during spinal anesthesia: an avoidable complication Rawéléguinbasba Armel Flavien Kabore,1 Ibrahim Alain Traore,2 Salah Idriss Séif Traore,3 Cheik Tidiane Hafi Wind-Pouiré Bougouma,1 Pascal Augustin,4 Aboudoul-Fataou Ouro-Bang’na Maman5 1Department of Anesthesia, University Hospital Blaise Comparoé, Ouagadougou, Burkina Faso; 2Department of Anesthesia, Uiversity...

A Formal Study of Boolean Games with Random Formulas as Payoff Functions

In this paper, we present a probabilistic analysis of Boolean games. We consider the class of Boolean games where payoff functions are given by random Boolean formulas. This permits to study certain properties of this class in its totality, such as the probability of existence of a winning strategy, including its asymptotic behaviour. With the help of the Coq proof assistant, we...

The provision of urban green space and its accessibility: Spatial data effects in Brussels

Urban green space (UGS) has many environmental and social benefits. UGS provision and access are increasingly considered in urban policies and must rely on data and indicators that can capture variations in the distribution of UGS within cities. There is no consensus about how UGS, and their provision and access, must be defined from different land use data types. Here we...

Photon sector analysis of Super and Lorentz symmetry breaking: effective photon mass, bi-refringence and dissipation

Within the standard model extension (SME), we expand our previous findings on four classes of violations of Super-Symmetry (SuSy) and Lorentz Symmetry (LoSy), differing in the handedness of the Charge conjugation-Parity-Time reversal (CPT) symmetry and in whether considering the impact of photinos on photon propagation. The violations, occurring at the early universe high...

Pharmacokinetics of intramuscular alfaxalone and its echocardiographic, cardiopulmonary and sedative effects in healthy dogs

The pharmacokinetics and the effects of a single intramuscular (IM) dose of alfaxalone on sedation and cardiopulmonary and echocardiographic variables was studied in dogs. Twelve healthy adult Beagles (3 females, 9 males) were used in this prospective controlled cross-over trial. Echocardiography was performed with and without 4 mg kg-1 alfaxalone IM with a week wash-out interval...

Using farmers' local knowledge of tree provision of ecosystem services to strengthen the emergence of coffee-agroforestry landscapes in southwest China

Intensive monoculture coffee farms quickly expanded in Yunnan Province in the 1990’s and 2000’s. In 2012, local authorities in Pu’er and Xishuangbanna Prefectures, the main coffee producing centre in the province, initiated a large-scale conversion program of these farms towards coffee-agroforestry systems to promote “ecologically-friendly coffee”. Shade tree inventories and...

The challenge of using date branch waste as a peat substitute in container nursery production of lettuce (Lactuca sativa L.)

PurposePeat-based substrates constitute the preferred media in conventional and organic nursery production. Nevertheless, in recent years, there has been a growing interest in environmental impacts associated with peat extraction that has increased with the demand of these non-renewable substrates. The re-use of organic wastes as substrate seems to be good solution to substitute...

Fine-Grain Iterative Compilation for WCET Estimation

Compiler optimizations, although reducing the execution times of programs, raise issues in static WCET estimation techniques and tools. Flow facts, such as loop bounds, may not be automatically found by static WCET analysis tools after aggressive code optimizations. In this paper, we explore the use of iterative compilation (WCET-directed program optimization to explore the...

The prevalence of brucellosis and bovine tuberculosis in ruminants in Sidi Kacem Province, Morocco

Bovine tuberculosis (BTB) and brucellosis are major endemic zoonoses in ruminants in Morocco that impact on both animal and human health. This study presents an assessment of the epidemiological and socioeconomic burden of bacterial zoonoses in Sidi Kacem Province in Northern Morocco from a cross-sectional survey of 125 cattle and/or small ruminant-owning households. In total...

Keratinocyte stem cells are more resistant to UVA radiation than their direct progeny

The epidermis undergoes constant renewal during its lifetime. This is possible due to a special population of keratinocyte stem cells (KSCs) located at the basal layer. These cells are surrounded by their direct progeny, keratinocyte progenitors or transient amplifying cells (TAs), which arise from cell division. Skin is exposed every day to sun radiation; in particular, UVA...

Complication patterns in patients undergoing venoarterial extracorporeal membrane oxygenation in intensive care unit: Multiple correspondence analysis and hierarchical ascendant classification

Background Treatment by venoarterial extracorporeal membrane oxygenation (VA-ECMO) is widely used today, even though it is associated with high risks of complications and death. While studies have focused on the relationship between some of these complications and the risk of death, the relationship between different complications has never been specifically examined, despite the...

Effects of positive end-expiratory pressure strategy in supine and prone position on lung and chest wall mechanics in acute respiratory distress syndrome

BackgroundIn acute respiratory distress syndrome (ARDS) patients, it has recently been proposed to set positive end-expiratory pressure (PEEP) by targeting end-expiratory transpulmonary pressure. This approach, which relies on the measurement of absolute esophageal pressure (Pes), has been used in supine position (SP) and has not been investigated in prone position (PP). Our...