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Exposure time, running and skill-related performance in international u20 rugby union players during an intensified tournament

Purpose This study investigated exposure time, running and skill-related performance in two international u20 rugby union teams during an intensified tournament: the 2015 Junior World Rugby Championship. Method Both teams played 5 matches in 19 days. Analyses were conducted using global positioning system (GPS) tracking (Viper 2™, Statsports Technologies Ltd) and event coding (Opta ...

Evaluating the glucose raising effect of established loci via a genetic risk score

Recent genome-wide association studies have identified several single nucleotide polymorphisms (SNPs) associated with glucose levels. We tested the hypothesis here whether the cumulative effect of glucose raising SNPs, assessed via a score, is associated with glucose levels. A total of 1,434 participants of Greek descent from the THISEAS study and 1,160 participants form the GOMAP ...

A regional case in the development of agriculture and crop processing in northern China from the Neolithic to Bronze Age: archaeobotanical evidence from the Sushui River survey, Shanxi province

The article presents the results of the analysis of survey archaeobotany samples from the Sushui valley. This provides evidence for changes over time for a region in the proportions of crops, especially rice versus millets. In addition, the composition of samples, both grouped by period and considered on a sample-by-sample basis, are considered as representing routine ...

Transition Densities and Traces for Invariant Feller Processes on Compact Symmetric Spaces

We find necessary and sufficient conditions for a finite K–bi–invariant measure on a compact Gelfand pair (G,K) to have a square–integrable density. For convolution semigroups, this is equivalent to having a continuous density in positive time. When (G,K) is a compact Riemannian symmetric pair, we study the induced transition density for G–invariant Feller processes on the ...

Nutrient limitations to bacterial and fungal growth during cellulose decomposition in tropical forest soils

Nutrients constrain the soil carbon cycle in tropical forests, but we lack knowledge on how these constraints vary within the soil microbial community. Here, we used in situ fertilization in a montane tropical forest and in two lowland tropical forests on contrasting soil types to test the principal hypothesis that there are different nutrient constraints to different groups of ...

Risky decision-making and affective features of impulse control disorders in Parkinson’s disease

Impulse control disorders (ICDs) in Parkinson’s disease (PD) are considered dopaminergic treatment side effects. Cognitive and affective factors may increase the risk of ICD in PD. The aim is to investigate risky decision-making and associated cognitive processes in PD patients with ICDs within a four-stage conceptual framework. Relationship between ICDs and affective factors was ...

Prevalence of markers of HIV infection among febrile adults and children in Bo, Sierra Leone, 2012–2013

Objective The goal of this study was to examine the prevalence of HIV among febrile patients seeking care in Mercy Hospital, Bo, Sierra Leone, in 2012–2013. Results A total of 1207 febrile persons were tested for HIV with Determine™ and SD Bioline rapid diagnostic tests kits that detect the presence of HIV antibodies and HIV p24 antigens. The overall prevalence of HIV among the ...

The effect of tranexamic acid on blood loss and maternal outcome in the treatment of persistent postpartum hemorrhage: A nationwide retrospective cohort study

Background Recent results show a protective effect of tranexamic acid on death due to bleeding in patients with postpartum hemorrhage in low- and middle-resource countries. We quantify the association between early administration of tranexamic acid compared to late or no administration and severe acute maternal morbidity and blood loss among women suffering from persistent severe ...

A real time metabolomic profiling approach to detecting fish fraud using rapid evaporative ionisation mass spectrometry

Introduction Fish fraud detection is mainly carried out using a genomic profiling approach requiring long and complex sample preparations and assay running times. Rapid evaporative ionisation mass spectrometry (REIMS) can circumvent these issues without sacrificing a loss in the quality of results. Objectives To demonstrate that REIMS can be used as a fast profiling technique ...

Acute and repetitive fronto-cerebellar tDCS stimulation improves mood in non-depressed participants

Transcranial direct current stimulation (tDCS) is a non-invasive form of brain stimulation, which allows for selective inhibition or excitation of neural structures. It has demonstrated some efficacy in the treatment of mood disorders. However, these studies have predominately focused on stimulation of the prefrontal cortex (PFC). The cerebellum has an increasingly recognized role ...

Measurement of the triple-differential dijet cross section in proton-proton collisions at \(\sqrt{s}=8\,\text {TeV} \) and constraints on parton distribution functions

A measurement is presented of the triple-differential dijet cross section at a centre-of-mass energy of 8\(\,\text {TeV}\) using 19.7\(\,\text {fb}^\text {-1}\) of data collected with the CMS detector in proton-proton collisions at the LHC. The cross section is measured as a function of the average transverse momentum, half the rapidity separation, and the boost of the two leading ...

Hormonal contraceptives and risk of ischemic stroke in women with migraine: a consensus statement from the European Headache Federation (EHF) and the European Society of Contraception and Reproductive Health (ESC)

Several data indicate that migraine, especially migraine with aura, is associated with an increased risk of ischemic stroke and other vascular events. Of concern is whether the risk of ischemic stroke in migraineurs is magnified by the use of hormonal contraceptives. As migraine prevalence is high in women of reproductive age, it is common to face the issue of migraine and hormonal ...

Delayed diagnosis of transanal prolapse of an ileo-colic intussusception in a 10-month-old infant in rural Cameroon: a case report

Background Transanal protrusion of intussusception is a complication of intussusception which involves the exteriorization of the apex of the intussusceptum through the anus. However, it is rarely reported and its confusion with rectal prolapse often leads to a diagnostic delay. Case presentation A 10-month-old female with no significant past history from a rural area in the ...

Phenome-wide association study using research participants’ self-reported data provides insight into the Th17 and IL-17 pathway

A phenome-wide association study of variants in genes in the Th17 and IL-17 pathway was performed using self-reported phenotypes and genetic data from 521,000 research participants of 23andMe. Results replicated known associations with similar effect sizes for autoimmune traits illustrating self-reported traits can be a surrogate for clinically assessed conditions. Novel ...

Measurements of the associated production of a Z boson and b jets in pp collisions at \({\sqrt{s}} = 8\,\text {TeV} \)

Measurements of the associated production of a \(\mathrm{Z}\) boson with at least one jet originating from a b quark in proton–proton collisions at \(\sqrt{s} = 8\,\text {TeV} \) are presented. Differential cross sections are measured with data collected by the CMS experiment corresponding to an integrated luminosity of 19.8\(\,\text {fb}^{-1}\). \(\mathrm{Z}\) bosons are ...

Pomalidomide with Dexamethasone for Treating Relapsed and Refractory Multiple Myeloma Previously Treated with Lenalidomide and Bortezomib: An Evidence Review Group Perspective of an NICE Single Technology Appraisal

The National Institute for Health and Care Excellence (NICE), as part of the institute’s single technology appraisal (STA) process, invited the manufacturer of pomalidomide (POM; Imnovid®, Celgene) to submit evidence regarding the clinical and cost effectiveness of the drug in combination with dexamethasone (POM + LoDEX) for the treatment of relapsed and refractory multiple myeloma ...

The effect of sodium/glucose cotransporter 2 (SGLT2) inhibition on the urinary proteome

Treatment with empagliflozin, an inhibitor of the sodium/glucose cotransporter 2 (SGLT2), is associated with slower progression of diabetic kidney disease. In this analysis, we explored the hypothesis that empagliflozin may have an impact on urinary peptides associated with chronic kidney disease (CKD). In this post-hoc, exploratory analysis, we investigated urine samples obtained ...

Evaluation of formability and fracture of pure titanium in incremental sheet forming

A forming limit diagram (FLD) is commonly used as a useful means for characterising the formability of sheet metal forming processes. In this study, the Nakajima test was used to construct the forming limit curve at necking (FLCN) and fracture (FLCF). The results of the FLCF are compared with incremental sheet forming (ISF) to evaluate the ability of the Nakajima test to describe ...