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Accuracy of glomerular filtration rate equations for chronic kidney disease patients at the G3a stage: a single-center cross-sectional study

Background Kidney disease improving global outcomes provided a new classification for chronic kidney disease (CKD) by subdividing the G3 stage into G3a and G3b stages based on glomerular filtration rate (GFR) in 2012. Currently, a few methods are used to evaluate GFR, including measured GFR (mGFR) and estimated GFR (eGFR). One of the mGFR was 99mTc-DTPA scintigraphy method and eGFR ...

The Use of APS Thermal Barrier Coatings in Corrosive Environments

Thermal barrier coatings (TBC) can be used to reduce the metal temperature of gas turbine blades enabling higher Cr alloys (lower strength) to be used when gas turbines are to be used in corrosive environments (where hot corrosion resistance is required). However, the TBC must also be resistant to the corrosive environment and remain attached to the blade. A 1000 h test to evaluate ...

A Comprehensive Performance Evaluation of Deformable Face Tracking “In-the-Wild”

Recently, technologies such as face detection, facial landmark localisation and face recognition and verification have matured enough to provide effective and efficient solutions for imagery captured under arbitrary conditions (referred to as “in-the-wild”). This is partially attributed to the fact that comprehensive “in-the-wild” benchmarks have been developed for face detection, ...

On \(C^\infty \) well-posedness of hyperbolic systems with multiplicities

In this paper, we study first-order hyperbolic systems of any order with multiple characteristics (weakly hyperbolic) and time-dependent analytic coefficients. The main question is when the Cauchy problem for such systems is well-posed in \(C^{\infty }\) and in \({\mathcal {D}}'\). We prove that the analyticity of the coefficients combined with suitable hypotheses on the ...

Are Quality-Adjusted Life Years a Good Proxy Measure of Individual Capabilities?

Background There is a debate in the health economics literature concerning the most appropriate way of applying Amartya Sen’s capability approach in economic evaluation studies. Some suggest that quality-adjusted life years (QALYs) alone are adequate while others argue that this approach is too narrow and that direct measures of capability wellbeing provide a more extensive ...

Efficient Bayesian compressed sensing-based channel estimation techniques for massive MIMO-OFDM systems

Efficient and highly accurate channel state information (CSI) at the base station (BS) is essential to achieve the potential benefits of massive multiple input multiple output (MIMO) systems. However, the achievable accuracy that is attainable is limited in practice due to the problem of pilot contamination. It has recently been shown that compressed sensing (CS) techniques can ...

Laser spectroscopy with an electrostatic ConeTrap

A compact electrostatic trap has been designed and installed as part of the recent upgrades to the IGISOL IV facility. The ConeTrap provides an in vacuo optical pumping site for low energy (800 eV) ionic ensembles available for interaction periods of 10-100 ms. At present, 6.7(3) % of injected mass A=98 ions can be trapped, stored for 5 ms, extracted and transported to a laser-ion ...

Modelling of friction stir welding of DH36 steel

A 3-D computational fluid dynamics (CFD) model was developed to simulate the friction stir welding of 6-mm plates of DH36 steel in an Eulerian steady-state framework. The viscosity of steel plate was represented as a non-Newtonian fluid using a flow stress function. The PCBN-WRe hybrid tool was modelled in a fully sticking condition with the cooling system effectively represented ...

Incidence of macrolide–lincosamide–streptogramin B resistance amongst beta-haemolytic streptococci in The Gambia

Background In West Africa, penicillin, macrolide and lincosamide resistance among beta-haemolytic streptococci (BHS) isolates has rarely been described. However, such data are critical to detect and track the emergence of antibiotic resistance. Methods Beta-haemolytic streptococci were cultured from clinical specimens from patients attending the clinic at the Medical Research ...

Cardiovascular Effects of Stimulant and Non-Stimulant Medication for Children and Adolescents with ADHD: A Systematic Review and Meta-Analysis of Trials of Methylphenidate, Amphetamines and Atomoxetine

Background Many children and adolescents with attention deficit/hyperactivity disorder (ADHD) are treated with stimulant and non-stimulant medication. ADHD medication may be associated with cardiovascular effects. It is important to identify whether mean group effects translate into clinically relevant increases for some individual patients, and/or increase the risk for serious ...

Net, excess and absolute adsorption in mixed gas adsorption

The formulation of a thermodynamic framework for mixtures based on absolute, excess or net adsorption is discussed and the qualitative dependence with pressure and fugacity is used to highlight a practical issue that arises when extending the formulations to mixtures and to the Ideal Adsorbed Solution Theory (IAST). Two important conclusions are derived: the correct fundamental ...

Behavioural Susceptibility Theory: Professor Jane Wardle and the Role of Appetite in Genetic Risk of Obesity

Purpose of Review There is considerable variability in human body weight, despite the ubiquity of the ‘obesogenic’ environment. Human body weight has a strong genetic basis and it has been hypothesised that genetic susceptibility to the environment explains variation in human body weight, with differences in appetite being implicated as the mediating mechanism; so-called ...

Calcipotriol Plus Betamethasone Dipropionate Aerosol Foam in Patients with Moderate-to-Severe Psoriasis: Sub-Group Analysis of the PSO-ABLE Study

Background Fixed-combination calcipotriol 50 μg/g plus betamethasone 0.5 mg/g (Cal/BD) aerosol foam is a new topical treatment for psoriasis. Although moderate-to-severe psoriasis is typically treated with systemic/biologic therapies, a topical treatment that is efficacious in these patients may be a significant cost-saving alternative to systemic therapy. Objective The objective ...

Burning Issues: Cremation and Incineration in Modern India

The cremation of human bodies and the incineration of urban waste provide two interrelated examples of technologies using the destructive power of fire that “travelled” in both directions between India and the West in the nineteenth and twentieth centuries. Rather than granting an automatic ascendency to western ways of burning the dead or disposing of urban rubbish, these case ...

A non-cooperative foundation for the continuous Raiffa solution

This paper provides a non-cooperative foundation for (asymmetric generalizations of) the continuous Raiffa solution. Specifically, we consider a continuous-time variation of the classic Ståhl–Rubinstein bargaining model, in which there is a finite deadline that ends the negotiations, and in which each player’s opportunity to make proposals is governed by a player-specific Poisson ...

Seeking evidence of multidisciplinarity in environmental geochemistry and health: an analysis of arsenic in drinking water research

A multidisciplinary approach to research affords the opportunity of objectivity, creation of new knowledge and potentially a more generally acceptable solution to problems that informed the research in the first place. It increasingly features in national programmes supporting basic and applied research, but for over 40 years, has been the arena for many research teams in ...

Standards for the Reporting of Genetic Counseling Interventions in Research and Other Studies (GCIRS): an NSGC Task Force Report

As the demand for evidence to support the value of genetic counseling increases, it is critical that reporting of genetic counseling interventions in research and other types of studies (e.g. process improvement or service evaluation studies) adopt greater rigor. As in other areas of healthcare, the appraisal, synthesis, and translation of research findings into genetic counseling ...

Genotype–phenotype mapping implications for genetic programming representation: Commentary on “On the mapping of genotype to phenotype in evolutionary algorithms” by Peter A. Whigham, Grant Dick, and James Maclaurin

Here we comment on the article “On the mapping of genotype to phenotype in evolutionary algorithms,” by Peter A. Whigham, Grant Dick, and James Maclaurin. The article reasons about analogies from molecular biology to evolutionary algorithms and discusses conditions for biological adaptations in the context of grammatical evolution, which provide a useful perspective to GP ...

High-Temperature Decomposition of Fe- and Cr-Doped NiO Produced by a Novel Flame Spray Technique

A novel thick film technology has been developed for the manufacture of electric heating elements from partially oxidised Ni–Cr–Fe alloy powder. The sprayed films were a mixture of metallic alloys and Ni-based oxides. Electron microscopy and analysis were used to monitor the transformations in the films during subsequent heat treatment. In particular, it was found that homogeneous ...