Advanced search    

Search: *

50,505 papers found. Showing first 1,000 results.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Meekunnen

Als u dit leest, is er net – 24 april – een interessant rapport van de WRR verschenen: ‘Weten is nog geen doen.

Instituut voor publieke waarden

Yvonne is diep ongelukkig. Weer een afwijzing. Laatst probeerde ze het voor de vierde keer. Telkens was het spannend. Telkens moest ze een drempel over. Maar ze ging toch naar de sociale dienst. Want ze had die uitkering echt nodig. Iedere keer maakte ze braaf aantekeningen tijdens de workshop. Haar c.v. op orde brengen, solliciteren, en de opdracht invullen. Ze begreep het ...

‘Je kinderen beschermen tegen beslagleggingen’

Olof Warners en zijn gezin zitten vanaf 2010 in de schulden. Hij heeft slechts vijf procent zicht. Zijn vrouw is in zorg vanwege ernstige angststoornissen.

Ontzorg je vlog

Vloggen is hip. Er zijn zelfs trainingen voor bijvoorbeeld sociaal werkers. Zij geven zo inzicht in hun werk, wat ze doen en waarom.

Stop de radicalisering

Venray-watcher Stan Verhaag verheugt zich op een goede discussie met ouders over hoe je jongeren weerbaar maakt tegen radicalisering.

The social and scientific values that shape national climate scenarios: a comparison of the Netherlands, Switzerland and the UK

This paper seeks to understand why climate information is produced differently from country to country. To do this, we critically examined and compared the social and scientific values that shaped the production of three national climate scenarios in the Netherlands, Switzerland and the UK. A comparative analysis of documentary materials and expert interviews linked to the climate ...

Exploring the relationship between perceived barriers to healthy eating and dietary behaviours in European adults

Purpose Dietary behaviours may be influenced by perceptions of barriers to healthy eating. Using data from a large cross-European study (N = 5900), we explored associations between various perceived barriers to healthy eating and dietary behaviours among adults from urban regions in five European countries and examined whether associations differed across regions and ...

Understanding Action and Adventure Sports Participation—An Ecological Dynamics Perspective

Previous research has considered action and adventure sports using a variety of associated terms and definitions which has led to confusing discourse and contradictory research findings. Traditional narratives have typically considered participation exclusively as the pastime of young people with abnormal characteristics or personalities having unhealthy and pathological tendencies ...

The Utrecht cohort for Multiple BREast cancer intervention studies and Long-term evaLuAtion (UMBRELLA): objectives, design, and baseline results

Purpose In oncology, RCTs are often beset by slow recruitment, limited generalizability, and strong preferences for interventions by patients and physicians. The cohort multiple randomized controlled trial (cmRCT) is an innovative design with the potential to overcome those challenges. In cmRCT, a prospective cohort serves as an infrastructure for multiple RCTs. We implemented ...

Prevalence, predictors, and prognostic implications of residual impairment of functional capacity after transcatheter aortic valve implantation

Background Patients with degenerative aortic stenosis (AS) referred for transcatheter aortic valve implantation (TAVI) typically have advanced cardiac and vascular adverse remodeling and multiple comorbidities and, therefore, might not recover a normal functional capacity after valve replacement. We sought to investigate the prevalence, the predictors, and the prognostic impact of ...

Current MitraClip experience, safety and feasibility in the Netherlands

Purpose Data on MitraClip procedural safety and efficacy in the Netherlands are scarce. We aim to provide an overview of the Dutch MitraClip experience. Methods We pooled anonymised demographic and procedural data of 1151 consecutive MitraClip patients, from 13 Dutch hospitals. Data was collected by product specialists in collaboration with local operators. Effect on mitral ...

Aberrant DNA methylation and expression of SPDEF and FOXA2 in airway epithelium of patients with COPD

Background Goblet cell metaplasia, a common feature of chronic obstructive pulmonary disease (COPD), is associated with mucus hypersecretion which contributes to the morbidity and mortality among patients. Transcription factors SAM-pointed domain-containing Ets-like factor (SPDEF) and forkhead box protein A2 (FOXA2) regulate goblet cell differentiation. This study aimed to (1) ...

Study protocol on the role of intestinal microbiota in colorectal cancer treatment: a pathway to personalized medicine 2.0

Purpose Investigate in patients with metastatic and/or irresectable colorectal cancer treated with systemic treatment with capecitabine or TAS-102 whether:1. Intestinal microbiota composition can act as a predictor for response. 2. Intestinal microbiota composition changes during systemic treatment and its relation to chemotoxicity. Background Gut microbiota and host determinants ...

Boundaries of the thoracic paravertebral space: potential risks and benefits of the thoracic paravertebral block from an anatomical perspective

Purpose Thoracic paravertebral block (TPVB) may be an alternative to thoracic epidural analgesia. A detailed knowledge of the anatomy of the TPV-space (TPVS), content and adnexa is essential in understanding the clinical consequences of TPVB. The exploration of the posterior TPVS accessibility in this study allows (1) determination of the anatomical boundaries, content and adnexa, ...

Three-dimensional virtual planning of corrective osteotomies of distal radius malunions: a systematic review and meta-analysis

The purpose of this study was to summarize and evaluate results of three-dimensional (3D-) planned corrective osteotomies of malunited distal radius fractures. 3D-planning techniques provide the possibility to address 3D-deformity that conventional planning methods might not address. We systematically searched PubMed, EMBASE and the Cochrane library for studies that performed a ...

Continuity vs. the Crowd—Tradeoffs Between Continuous and Intermittent Citizen Hydrology Streamflow Observations

Hydrologic data has traditionally been collected with permanent installations of sophisticated and accurate but expensive monitoring equipment at limited numbers of sites. Consequently, observation frequency and costs are high, but spatial coverage of the data is limited. Citizen Hydrology can possibly overcome these challenges by leveraging easily scaled mobile technology and ...

The elusive role of B lymphocytes and islet autoantibodies in (human) type 1 diabetes

The role of B lymphocytes in the pathogenesis of type 1 diabetes in humans is not entirely evident. These cells are presumed to be important, but this assumption is largely based on animal models of autoimmune diabetes, where compelling evidence for the contribution of both B lymphocytes and insulin-specific autoantibodies to this disease is in place. For humans, this is much less ...

Evaluation of hip abductor and adductor strength in the elderly: a reliability study

Background In elderly individuals an increased muscle strength contributes to the diminution of the falls risk and associated adverse events. An increasing interest in lateral control exists due to the fatal consequences of postero-lateral falls. Therefore a proper assessment of frontal plane hip muscle strength in elderly is important but remains challenging. Therefore we aimed to ...

Sequence Learning Enhancement Following Single-Session Meditation Is Dependent on Metacontrol Mode and Experienced Effort

Focused attention (FAM) and open monitoring (OMM) meditation types establish distinct metacontrol states that have immediate effects on how attention allocation strategies are utilised in subsequent, unrelated tasks. Because attention allocation is a central factor in sequential action, the present experiment investigated whether a single-session of FAM and OMM enhanced subsequent ...