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Do general innovation policy tools fit all? Analysis of the regional impact of the Norwegian Skattefunn scheme

Background The paper examines the regional effects of a general innovation policy, i.e. a policy tool that does not target specific industries or subnational regions. General policy tools are an important part of the portfolio of innovation policy measures. However, there is a question over whether general tools are equally relevant for all types of firms, irrespective of their ...

Optimal nitrogen fertilization of boreal conifer forest

Background Forest fertilization offers a means to increase the production of renewable resources. Nitrogen is the most common fertilizer in boreal upland forests. There is plenty of research on the effect of nitrogen fertilization on volume growth, but less research on the optimal timing of fertilization and optimal management of fertilized stands. Methods This study used ...

The micro-politics of small-scale fisheries governance in South Africa: a case study of community-based political representation as a form of brokerage

The right of small-scale fishers to participate in governance and management processes has been increasingly recognised by theorists and policy-makers over the last thirty years. Political representation is central to the realisation of the right to participation. In the context of small-scale fisheries, the first level of political representation is usually located within a ...

Construction of low-ethanol–wine yeasts through partial deletion of the Saccharomyces cerevisiae PDC2 gene

We propose an alternative GMO based strategy to obtain Saccharomyces cerevisiae mutant strains with a slight reduction in their ability to produce ethanol, but with a moderate impact on the yeast metabolism. Through homologous recombination, two truncated Pdc2p proteins Pdc2pΔ344 and Pdc2pΔ519 were obtained and transformed into haploid and diploid lab yeast strains. In the pdc2Δ344 ...

Bending back stress chains and unique behaviour of granular matter in cylindrical geometries

We analyse the general solutions for the stress field in planar annuli of isostatic media, a model often used for marginally rigid granular materials in Couette cells. We demonstrate that these solutions are much richer than in rectangular symmetries. Even for uniform media, stress chains are found to curve, broaden away from the stress source, attenuate and leak stress into a cone ...

Phytase production by Aspergillus niger NCIM 563 for a novel application to degrade organophosphorus pesticides

The production of phytase using Aspergillus niger NCIM 563 under submerged fermentation conditions was studied using protein rich chickpea flour as substrate. Employing a hybrid statistical media optimization strategy of Plackett–Burman and Box-Behnken experimental designs in shake-flasks gave an increased phytase activity from an initial 66 IU/mL in 216 h to 160 IU/mL in a reduced ...

Perception of smile esthetics by laypeople of different ages

Background Age is a factor affecting smile esthetics. Three variables of smile esthetics associated with the maxillary anterior teeth and age-related changes have recently received considerable attention: (i) the incisal edge position of the maxillary central incisors, (ii) the maxillary gingival display, and (iii) the presence of a black triangle between the maxillary central ...

Pricing Decision in a Two-Echelon Supply Chain with Competing Retailers Under Uncertain Environment

This paper explores a supply chain pricing competition problem in a two-echelon supply chain with one manufacturer and two competing retailers. The manufacturing costs, sales costs, and market bases are all characterized as uncertain variables whose distributions are estimated by experts’ experienced data. In consideration of channel members’ different market powers, three ...

Large-area fluidic assembly of single-walled carbon nanotubes through dip-coating and directional evaporation

We present a simple and scalable fluidic-assembly approach, in which bundles of single-walled carbon nanotubes (SWCNTs) are selectively aligned and deposited by directionally controlled dip-coating and solvent evaporation processes. The patterned surface with alternating regions of hydrophobic polydimethyl siloxane (PDMS) (height ~ 100 nm) strips and hydrophilic SiO2 substrate was ...

Assimilates mobilization, stable canopy temperature and expression of expansin stabilizes grain weight in wheat cultivar LOK-1 under different soil moisture conditions

Background Grain yield of wheat is primarily determined by both grain number and grain weight, which often influence each other in response to environmental stimuli. Some of the genotypes are capable of maintaining high single grain weight (SGW) across the environments. Understanding mechanisms and factors associated with the superiority of such genotypes over others is necessary ...

Laparoscopic anterior gastropexy for type III/IV hiatal hernia in elderly patients

Introduction Large esophageal hiatal hernias occur most commonly in elderly patients with comorbidities, in whom even an elective surgery cannot be performed without high risks. Although fundoplication is recommended for esophageal hiatal hernia repair, we prefer not to limit our options to fundoplication, as obstruction is a frequent main complaint. We favor an anterior gastropexy ...

Damage from lava flows: insights from the 2014–2015 eruption of Fogo, Cape Verde

Fast-moving lava flows during the 2014–2015 eruption of Fogo volcano in Cape Verde engulfed 75% (n = 260) of buildings within three villages in the Chã das Caldeiras area, as well as 25% of cultivable agricultural land, water storage facilities and the only road into the area. The eruption had a catastrophic impact for the close-knit communities of Chã, destroying much of their ...

Using integrated correlative cryo-light and electron microscopy to directly observe syntaphilin-immobilized neuronal mitochondria in situ

Correlative cryo-fluorescence and cryo-electron microscopy (cryo-CLEM) system has been fast becoming a powerful technique with the advantage to allow the fluorescent labeling and direct visualization of the close-to-physiologic ultrastructure in cells at the same time, offering unique insights into the ultrastructure with specific cellular function. There have been various ...

Attitudes among older drivers towards medical assessment at renewal of driving license in Sweden

Purpose The aim was to examine attitudes among older adults in Sweden as regards a possible legislation for medical assessment at license renewal depending on their health status (vision and hearing) and gender. Methods A questionnaire study measuring attitudes towards medical assessments at license renewal and an examination of vision, hearing, and cognitive abilities was ...

Uncommon features of surgically resected ALK-positive cavitary lung adenocarcinoma: a case report

Some features found on chest computed tomography (CT), such as central tumor location, large pleural effusion, and the absence of a pleural tail, and a patient age of less than 60 years, have been suggested to be useful in predicting anaplastic lymphoma kinase (ALK) rearrangement in patients with non-small cell lung cancer (NSCLC). A 68-year-old female patient with a history of ...

A CPN/B method transformation framework for railway safety rules formal validation

This paper presents a “CPN/B method” based process for railway systems safety analysis. Achieving interoperability through the European Rail Traffic Management System (ERTMS/ETCS) is facing difficulties in railway safety assessment due to the interaction of national and European operating specifications. These specifications have been modeled using several formalisms, which makes ...

Multimodality management and outcomes of brain arterio-venous malformations (AVMs) in children: personal experience and review of the literature, with specific emphasis on age at first AVM bleed

Purpose The purpose of this paper is to study the presentation and analyse the results of multimodality treatment of brain arterio-venous malformations (AVMs) in children at our centre and review age at first AVM rupture in the literature. Methods Of 52 patients aged <18 years, 47 with brain AVMs (27 males and 20 females) aged 4–17 years (mean 12.2) were retrospectively reviewed. ...

Reusable specification templates for defining dynamic semantics of DSLs

In the context of model-driven engineering, the dynamic (execution) semantics of domain-specific languages (DSLs) is usually not specified explicitly and stays (hard)coded in model transformations and code generation. This poses challenges such as learning, debugging, understanding, maintaining, and updating a DSL. Facing the lack of supporting tools for specifying the dynamic ...

Adherence to pediatric diabetic ketoacidosis guidelines by community emergency departments’ providers

Background Diabetic ketoacidosis (DKA) is a common presentation of type I diabetes mellitus to the emergency departments. Most children with DKA are initially managed in community emergency departments where providers may not have easy access to educational resources or pediatric-specific guidelines and protocols that are readily available at pediatric academic medical centers. The ...