Advanced search    

Search: *

23,374 papers found. Showing first 1,000 results.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Designing in between Local Government and the Public – Using Institutional Analysis in Interventions on Civic Infrastructures

Adapting and changing the systems and technologies involved in civic engagement with local government is among the key challenges of collaborative technologies for political participation. In such contexts, both existing sets of technologies and ingrained, often formalised practices, the ‘rules of the game’, constrain any opportunity for intervention. Additionally, ‘civic’ and ...

European Criminal Law After Brexit

The victory for the ‘Brexit’ vote in the referendum last June has sent shockwaves around Europe. The initial shock has given way for some to the realisation of the legal and constitutional complexity of untangling the UK’s relationship with the EU and re-engineering this relationship for a post-Brexit era, an era when the UK will be a third country for the EU. The legal challenges ...

“Daring to Care”: Challenging Corporate Environmentalism

Corporate engagements with pressing environmental challenges focus on expanding the role of the market, seeking opportunities for growth and developing technologies to manage better environmental resources. Such approaches have proved ineffective. I suggest that a lack of meaningful response to ecological degradation and climate change is inevitable within a capitalist system ...

Purinergic signalling links mechanical breath profile and alveolar mechanics with the pro-inflammatory innate immune response causing ventilation-induced lung injury

Severe pulmonary infection or vigorous cyclic deformation of the alveolar epithelial type I (AT I) cells by mechanical ventilation leads to massive extracellular ATP release. High levels of extracellular ATP saturate the ATP hydrolysis enzymes CD39 and CD73 resulting in persistent high ATP levels despite the conversion to adenosine. Above a certain level, extracellular ATP ...

Physical and thermal properties of mud-dominant sediment from the Joetsu Basin in the eastern margin of the Japan Sea

Physical properties (bulk density and porosity) and thermal properties (thermal conductivity, heat capacity, specific heat, and thermal diffusivity) of sediment are crucial parameters for basin modeling. We measured these physical and thermal properties for mud-dominant sediment recovered from the Joetsu Basin, in the eastern margin of the Japan Sea. To determine thermal ...

Pre-Service Teachers’ Views of the Child—Reproducing or Challenging Gender Stereotypes in Science in Preschool

We report how 47 pre-service teachers during their preschool placement in Sweden identify events related to gender and emerging science. We analysed their reflections on the situations with Gee’s Discourse analysis. Two dominant discourse models were identified: the Discourse Construare, where pre-service teachers assumed that children have potential interests in a variety of ...

No net loss of what, for whom?: stakeholder perspectives to Biodiversity Offsetting in England

Market-based instruments (MBIs) have emerged as a popular approach to balance development and conservation objectives. However, their ability to accomplish this is often beset by poor implementation in practice. This is testament to a widening gap between the rate of policy development and implementation of MBIs and the maturity of research and evaluation on their design, and ...

Hasteners and delayers: why rains don’t cause fires

We typically judge that hasteners are causes of what they hasten, while delayers are not causes of what they delay. These judgements, I suggest, are sensitive to an underlying metaphysical distinction. To see this, we need to pay attention to a relation that I call positive security-dependence, where an event E security-depends positively on an earlier event C just in case E could ...

Pregnancy outcome in more than 5000 births to women with viral hepatitis: a population-based cohort study in Sweden

Previous studies have shown inconsistent results with respect to hepatitis B (HBV), hepatitis C (HCV) and pregnancy outcome. The aim of this study was to investigate pregnancy outcome in women with HBV or HCV. In a nationwide cohort of births between 2001 and 2011 we investigated the risks of adverse pregnancy outcomes in 2990 births to women with HBV and 2056 births to women with ...

Use of GC and PDSC methods to characterize human milk fat substitutes obtained from lard and milk thistle oil mixtures

The aim of this study was the analytical evaluations of human milk fat substitutes (HMFS) synthesized via enzymatic interesterification of lard and milk thistle oil mixtures by a immobilized commercial sn-1,3-specific lipase, using calorimetric and chromatographic methods. The mixtures of lard and milk thistle oil at mass ratio 6:4 and 8:2 were interesterified for 2, 4 and 6 h at ...

Predictive processing and the representation wars: a victory for the eliminativist (via fictionalism)

In this paper I argue that, by combining eliminativist and fictionalist approaches toward the sub-personal representational posits of predictive processing, we arrive at an empirically robust and yet metaphysically innocuous cognitive scientific framework. I begin the paper by providing a non-representational account of the five key posits of predictive processing ...

Fallow replacement and alternative nitrogen management for reducing nitrate leaching in a semiarid region

Nitrate (NO3 −) leaching into groundwater is a growing global concern for health, environmental, and economic reasons, yet little is known about the effects of agricultural management practices on the magnitude of leaching, especially in dryland semiarid regions. Groundwater nitrate–nitrogen (nitrate–N) concentrations above the drinking water standard of 10 mg L−1 are common in the ...

Observing and Simulating Wind-Turbine Wakes During the Evening Transition

Wind-turbine-wake evolution during the evening transition introduces variability to wind-farm power production at a time of day typically characterized by high electricity demand. During the evening transition, the atmosphere evolves from an unstable to a stable regime, and vertical stratification of the wind profile develops as the residual planetary boundary layer decouples from ...

Proline isomerization in the C-terminal region of HSP27

In mammals, small heat-shock proteins (sHSPs) typically assemble into interconverting, polydisperse oligomers. The dynamic exchange of sHSP oligomers is regulated, at least in part, by molecular interactions between the α-crystallin domain and the C-terminal region (CTR). Here we report solution-state nuclear magnetic resonance (NMR) spectroscopy investigations of the conformation ...

A Response to Coren’s Objections to the Principle of Alternate Possibilities as Sufficient but not Necessary for Moral Responsibility

In this paper I respond to Coren’s argument against my 2016 paper in which I present a case for the principle of alternate possibilities as sufficient but not necessary for the ascription of moral responsibility (PAP(S)). I concede that Coren has identified aspects of my original position that are vulnerable to counter-examples. Nevertheless, through a simple amendment to my ...

Effects of caffeine intake prior to stress cardiac magnetic resonance perfusion imaging on regadenoson- versus adenosine-induced hyperemia as measured by T1 mapping

The antagonistic effects of caffeine on adenosine receptors are a possible cause of false-negative stress perfusion imaging. The purpose of this study was to determine the effects of coffee intake <4 h prior to stress perfusion cardiac magnetic resonance imaging (CMR) in regadenoson- versus adenosine-induced hyperemia as measured with T1-mapping. 98 consecutive patients with ...

Photoplethysmography for blood volumes and oxygenation changes during intermittent vascular occlusions

Photoplethysmography (PPG) is an optical technique that measures blood volume variations. The main application of dual-wavelength PPG is pulse oximetry, in which the arterial oxygen saturation (SpO\(_2\)) is calculated noninvasively. However, the PPG waveform contains other significant physiological information that can be used in conjunction to SpO\(_2\) for the assessment of ...

Quantifying impacts of forecast uncertainties on predicted storm surges

In this paper, we propose a framework for quantifying risks, including (1) the effects of forecast errors, (2) the ability to resolve critical grid features that are important to accurate site-specific forecasts, and (3) a framework that can move us toward performance-based/cost-based decisions, within an extremely fast execution time. A key element presently lacking in previous ...