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Silverland: the Realm of Compounds of Divalent Silver—and Why They are Interesting

In this personal account, the author takes readers on the journey to “Silverland,” i.e., the emerging field of electronic and magnetic materials based on divalent silver (Ag2+). He blends historical background with the reasons which led him to become involved in this research, as well as to proposing (with Roald Hoffmann, 2001) that high-T C superconductivity might ultimately be ...

Some Liked It Hot: A Hypothesis Regarding Establishment of the Proto-Mitochondrial Endosymbiont During Eukaryogenesis

Eukaryotic cells are characterized by a considerable increase in subcellular compartmentalization when compared to prokaryotes. Most evidence suggests that the earliest eukaryotes consisted of mitochondria derived from an α-proteobacterial ancestor enclosed within an archaeal host cell. However, what benefits the archaeal host and the proto-mitochondrial endosymbiont might have ...

Acid–base safety during the course of a very low-calorie-ketogenic diet

Background and Aims Very low-calorie ketogenic (VLCK) diets have been consistently shown to be an effective obesity treatment, but the current evidence for its acid-base safety is limited. The aim of the current work was to evaluate the acid-base status of obese patients during the course of a VLCK diet. Method Twenty obese participants undertook a VLCK diet for 4 months. ...

Potential Effect of Prolonged Sevoflurane Anesthesia on the Kinetics of [11C]Raclopride in Non-human Primates

Purpose Positron emission tomography (PET) in non-human primates (NHP) is commonly performed under anesthesia, with sevoflurane being a widely used inhaled anesthetic. PET measurement in NHP can be repeated, and a difference in radioligand kinetics has previously been observed between the first and second PET measurement on the same day using sevoflurane anesthesia. In this study, ...

Hierarchical Heterostructure of ZnO@TiO2 Hollow Spheres for Highly Efficient Photocatalytic Hydrogen Evolution

The rational design and preparation of hierarchical nanoarchitectures are critical for enhanced photocatalytic hydrogen evolution reaction (HER). Herein, well-integrated hollow ZnO@TiO2 heterojunctions were obtained by a simple hydrothermal method. This unique hierarchical heterostructure not only caused multiple reflections which enhances the light absorption but also improved the ...

Exploring the motives and practices of university–start-up interaction: evidence from Route 128

This paper explores the concept of university–start-up interaction (USUI) as a source of knowledge spillover and innovation. In doing so, we bring together literature on three broad mechanisms that enable knowledge utilization: education, new venture support, and university–industry interaction (UII), as we argue that USUI is a process in which all three are relevant. We first ...

Impact of Physical Activity on Reporting of Childhood Asthma Symptoms

This study aims to determine the impact of physical activity on asthma symptom reporting among children living in an inner city. Among 147 children aged 5–12 years with physician-diagnosed asthma, we assessed asthma symptoms using twice-daily diaries and physical activity using the physical activity questionnaire for children during three 8-day periods (baseline, 3 and 6 months). ...

Pregabalin Misuse and Abuse in Jordan: a Qualitative Study of User Experiences

Pregabalin is currently approved for the treatment of epilepsy, generalized anxiety disorder, neuropathic pain, and fibromyalgia. A qualitative study was undertaken in Jordan, where concerns have been raised about its unprescribed availability in community pharmacies and thereby its abuse. Semi-structured interviews were conducted with all patients with a history of pregabalin use ...

Fostering self-regulation in training complex cognitive tasks

In complex cognitive domains such as air traffic control, professionals must be able to adapt to and act upon continuing changes in a highly advanced technological work environment. To function optimally in such an environment, the controllers must be able to regulate their learning. Although these regulation skills should be part of their training, this is not usually the case. ...

Dexlansoprazole for Heartburn Relief in Adolescents with Symptomatic, Nonerosive Gastro-esophageal Reflux Disease

Background Proton pump inhibitors are commonly used to treat gastro-esophageal reflux disease (GERD) and nonerosive GERD (NERD) in adolescents and adults. Despite the efficacy of available medications, many patients have persisting symptoms, indicating a need for more effective agents. Aims To assess the safety and efficacy of dexlansoprazole dual delayed-release capsules in ...

Utilization of a Novel Chitosan/Clay/Biochar Nanobiocomposite for Immobilization of Heavy Metals in Acid Soil Environment

An organic–inorganic composite of chitosan, nanoclay, and biochar (named as MTCB) was chosen to develop a bionanocomposite to simultaneously immobilize Cu, Pb, and Zn metal ions within the contaminated soil and water environments. The composite material was structurally and chemically characterized with the XRD, TEM, SEM, BET, and FT-IR techniques. XRD and TEM results revealed that ...

Land Use Alters the Drought Responses of Productivity and CO2 Fluxes in Mountain Grassland

Climate extremes and land-use changes can have major impacts on the carbon cycle of ecosystems. Their combined effects have rarely been tested. We studied whether and how the abandonment of traditionally managed mountain grassland changes the resilience of carbon dynamics to drought. In an in situ common garden experiment located in a subalpine meadow in the Austrian Central Alps, ...

The Past Ubiquity and Environment of the Lost Earth Buildings of Scotland

This paper investigates the once ubiquitous vernacular earth-built structures of Scotland and how perceptions of such buildings were shaped and developed through periods of intense cultural and environmental change. We focus upon the past exploitation of traditional resources to construct vernacular architectures and on changes in the perception of the resultant buildings. Historic ...

Physiological Ripples (± 100 Hz) in Spike-Free Scalp EEGs of Children With and Without Epilepsy

Pathological high frequency oscillations (HFOs, >80 Hz) are considered new biomarkers for epilepsy. They have mostly been recorded invasively, but pathological ripples (80–250 Hz) can also be found in scalp EEGs with frequent epileptiform spikes. Physiological HFOs also exist. They have been recorded invasively in hippocampus and neocortex. There are no reports of spontaneously ...

Organizational diversity and innovation potential of EU-funded research projects

Impact evaluations of collaborative research projects usually focus on private benefits of participants, e.g. their turnover or employment growth. We study the innovative performance of collaborative research projects and how it depends on the organizational diversity of participating organizations. Our population includes participants to EC-funded collaborative research projects ...

Quantification of the Intracellular Life Time of Water Molecules to Measure Transport Rates of Human Aquaglyceroporins

Orthodox aquaporins are transmembrane channel proteins that facilitate rapid diffusion of water, while aquaglyceroporins facilitate the diffusion of small uncharged molecules such as glycerol and arsenic trioxide. Aquaglyceroporins play important roles in human physiology, in particular for glycerol metabolism and arsenic detoxification. We have developed a unique system applying ...