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Paper-based electrochemical device for early detection of integrin αvβ6 expressing tumors

and high cost. Therefore, innovative diagnostic techniques that integrate knowledge from biology, oncology, medicinal and analytical chemistry are now quickly emerging in the attempt to address these ... synthetic and analytical chemistry, cancer biology and bioengineering, we developed a generalizable multi-disciplinary approach for liquid-biopsy on printed strip. A library of αvβ6 selective ligands

Meet the contributors of Young Investigators in (Bio-)Analytical Chemistry 2023

Investigators in (Bio-) Analytical Chemistry 2023 with guest editors Zhi-Yuan Gu, Beatriz Jurado-Sánchez, Thomas H. Linz, Leandro Wang Hantao, Nongnoot Wongkaew, and Peng Wu 1 Nicola Oberbeckmann-Winter 2 ... Analytical and Bioanalytical Chemistry , Springer, Tiergartenstrasse 17, 69121 Heidelberg , Germany This special issue features young investigators in (bio-)analytical science - it is the sixth edition

Meet the guest editors of Young Investigators in (Bio-)Analytical Chemistry 2023

Investigators in (Bio-) Analytical Chemistry 2023 with guest editors Zhi-Yuan Gu, Beatriz Jurado-Sánchez, Thomas H. Linz, Leandro Wang Hantao, Nongnoot Wongkaew, and Peng Wu 1 Nicola Oberbeckmann-Winter 2 ... Analytical and Bioanalytical Chemistry , Springer-Verlag, Tiergartenstrasse 17, 69121 Heidelberg , Germany For the sixth time, a special issue featuring Young Investigators in (Bio-)Analytical Chemistry has

Method operable design region for robust RP-HPLC analysis of pioglitazone hydrochloride and teneligliptin hydrobromide hydrate: incorporating hybrid principles of white analytical chemistry and design of experiments

chemistry. Teneligliptin and pioglitazone have not yet been simultaneously estimated using a chromatographic method that has been documented in the literature. A white analytical chemistry-assisted RP-HPLC ... analysis should have characteristics like robustness, eco-friendliness, cost-effectiveness, and user-friendliness following the recently developed idea of white analytical chemistry. Teneligliptin and

Environmentally benign liquid chromatographic method for concurrent estimation of four antihistaminic drugs applying factorial design approach

In the last few decades, green analytical chemistry (GAC) has become a smart magical solution for the qualification and quantification of many drugs. In the current study, a direct, sensitive, and ... of greenness assessment The Analytical Greenness (AGREE) is a metric novel green assessment method that depends on the 12 principles of green analytical chemistry (GAC), which are abbreviated as

Phenylpropanoid-enriched broccoli seedling extract can reduce inflammatory markers and pain behavior

aspects of mammalian metabolic processing, the OE was treated with the S9 liver microsome fraction derived from mouse, for use in a mouse in vivo study. Analytical chemistry was performed to identify major ... . Growth methods and experimental extractions led to an extract of mainly phenylpropanoids that were stable post-harvest. Extracted chemicals were identified by analytical chemistry. Experiments were

“Buddy check” peer observation activity for hands-on learning in analytical chemistry laboratories

activity was many students’ first ever pipet use, and since general chemistry students do not need to achieve the same level of precision as the second-year analytical students, this checklist was simplified ... analytical chemistry. Her pedagogical work includes the development of an open-access gene r a l ch e m i s t r y t ex t b o o k , undergraduate lab safety training, and supporting the development of graduate

Advances in green chemistry and engineering

greatly contribute to achieving sustainable development goals. To this end, many studies have been conducted to develop new approaches within green chemistry and engineering. The Advances in Green Chemistry ... and Engineering Collection at Scientific Reports aims at gathering the latest research on developing and implementing the principles of green chemistry and engineering. In the research areas of green

Stability indicating eco-friendly quantitation of terbutaline and its pro-drug bambuterol using quantitative proton nuclear magnetic spectroscopy

Quantitative 1H-NMR became an increasingly important issue in pharmaceutical analytical chemistry. This study used NMR spectroscopy to assay the bronchodilator drug terbutaline sulfate and its pro ... ; 22 ( 9 ): 1517 . 25. Miller JMJC , Statistics and Chemometrics for Analytical Chemistry. 2018 . 26. Tobiszewski M , et al. Green chemistry metrics with special reference to green analytical chemistry

The rise of data repositories in materials chemistry

optimise resource use, fostering a robust foundation for future scientific progress. Here, the authors explore the use of FAIR practices to advance materials chemistry research, examining key repositories ... in materials chemistry, and the wider scientific literature, are listed in Table 1. These repositories are suggested avenues of sharing by an example data science journal4 and targeted for general

Four chemometric models enhanced by Latin hypercube sampling design for quantification of anti-COVID drugs: sustainability profiling through multiple greenness, carbon footprint, blueness, and whiteness metrics

Montelukast sodium (MLK) and Levocetirizine dihydrochloride (LCZ) are widely prescribed medications with promising therapeutic potential against COVID-19. However, existing analytical methods for ... design, Greenness evaluation, Whiteness assessment, Blueness evaluation Introduction The analytical chemistry field faces pressing challenges regarding the environmental sustainability of conventional

Leveraging large language models for predictive chemistry

Machine learning has transformed many fields and has recently found applications in chemistry and materials science. The small datasets commonly found in chemistry sparked the development of ... ), Institut des Sciences et Ingénierie Chimiques, École Polytechnique Fédérale de Lausanne (EPFL) , Sion , Switzerland 1 Center for Energy and Environmental Chemistry Jena (CEEC Jena), Friedrich Schiller

Spectrofluorometric quantitative analysis of aripiprazole based on quenching of natural derived carbon quantum dots in spiked human plasma

sensitive and consistent with the principles of green analytical chemistry. ... University , Jeddah , Saudi Arabia 6 Department of Clinical Pharmacy, College of Pharmacy, Taif University , P.O. Box 11099, Taif 21944 , Saudi Arabia 7 Pharmaceutical Analytical Chemistry Department, Faculty

Green analytical chemistry and experimental design: a combined approach for the analysis of zonisamide

Green analytical chemistry principles, as well as experimental design, are a combined approach adopted to develop sensitive reproducible stability indicating HPLC method for Zonisamide (ZNS

Analytical evaluation of circulating tumor DNA sequencing assays

, demonstrating high analytical sensitivity. Variations in circulating tumor DNA extraction and quantification efficiency, sensitivity, and reproducibility were observed, particularly at lower inputs. These ... important for assay performance14. In 2021, an evaluation of the analytical performance of five ctDNA assays, which included evaluations at each stage of the ctDNA sequencing workflow using synthetic DNA

Reactive aldehyde chemistry explains the missing source of hydroxyl radicals

oxide and high volatile organic compound regimes even considering the latest isoprene chemistry. Here we propose that the reactive aldehyde chemistry, especially the autoxidation of carbonyl organic ... hydroperoxyl-carbonyls that generate OH through rapid photolysis. This chemistry could explain almost all unknown OH sources in areas rich in both natural and anthropogenic emissions in the warm seasons, and may

Green chromatographic methods for determination of co-formulated lidocaine hydrochloride and miconazole nitrate along with an endocrine disruptor preservative and potential impurity

Recently, green analytical chemistry (GAC) is a key issue towards the idea of sustainability, the analytical community is focused on developing analytical methods that incorporate green chemistry ... binary mixture of LDC and MIC along with MTP and DMA in presence of SAC. Green analytical chemistry (GAC) is a novel approach that emerged in 2000s [ 31 ]. This emerging discipline is concerned with

Making waves in analytical chemistry

Natural Resources and Life Sciences , Vienna (BOKU), Muthgasse 18, 1190 Vienna , Austria 1 Department of General, Analytical and Physical Chemistry, Chair of General and Analytical Chemistry ... , Montanuniversität Leoben, Franz-Josef-Straße 18, 8700 Leoben , Austria 2 Johanna Irrgeher 3 Department of Analytical Chemistry, Faculty of Chemistry, University of Vienna , Währinger Straße 38, 1090 Vienna , Austria

Analytical characterization of full, intermediate, and empty AAV capsids

imperative that intermediate and empty capsid impurities are identified, quantified, and controlled in clinical preparations. Central to this are effective analytical methods to measure the levels of these ... vitro and in vivo potency. MATERIALS AND METHODS The analytical toolbox used for AAV vector profile characterization in this study is summarized in Supplementary Table S1. Purified Drug Substance

Cosmic dust fertilization of glacial prebiotic chemistry on early Earth

Earth’s surface is deficient in available forms of many elements considered limiting for prebiotic chemistry. In contrast, many extraterrestrial rocky objects are rich in these same elements ... cryoconite sediments. Our results challenge the widely held assumption that cosmic dust is incapable of fertilizing prebiotic chemistry. Cosmic dust deposits may have plausibly formed on early Earth and acted