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Few long-term consequences after prolonged maternal separation in female Wistar rats

behavior, HPA axis activity and long-term voluntary alcohol intake in female rats. Litters were subjected to 15 min (MS15) or 360 min (MS360) of daily maternal separation during postnatal day 1–21. In ... . Behavioral profiles and stress-induced corticosteroid secretion in male Wistar rats subjected to short and prolonged periods of maternal separation . Horm Behav . 2006 ; 50 : 736 ± 747 .

Brain region-specific expression of genes mapped within quantitative trait loci for behavioral responsiveness to acute stress in Fisher 344 and Wistar Kyoto male rats

. Fischer 344 (F344) and Wistar Kyoto (WKY) rat strains show large differences in behavioral responsiveness to acute stress, such as freezing behavior in response to footshock during the conditioning phase of ... have studied the genetic components of behavioral responsiveness to acute stress in the reciprocally crossed F2 generation of Wistar Kyoto (WKY) and Fischer 344 (F344) rat strains using the defensive

Tobacco-Free Cigarette Smoke Exposure Induces Anxiety and Panic-Related Behaviours in Male Wistar Rats

without tobacco. Male Wistar rats were divided into the following groups: a control group (CG); a regular cigarette group (RC); and a tobacco-free cigarette (TFC) group. Animals were exposed to twelve ... investigate the effect of smoke exposure, and therefore, of lung damage, produced by regular and tobacco-free cigarettes (TFC) on anxiety and panic-associated behaviours in male Wistar rats. As regular

High-Fat Diet and Alcohol Intake Promotes Inflammation and Impairs Skin Wound Healing in Wistar Rats

skin wound healing in Wistar rats. Male rats () were individually housed in cages with food and water ad libitum (registration number 213/2014). After anesthesia, at day 40, three circular wounds (12 mm ... -fat diet and alcohol intake on skin wound healing mainly in the inflammatory phase. 2. Methods2.1. Animals Healthy ten-week-old male Wistar rats (Rattus norvegicus) weighing an average of 320 g were

The effect of age on five ions of the kidney in the Fischer 344 rat

toxicity observed in Materials and methods. Male Fischer 344 rats (90, 180, 365, 790 and 840 days old) were raised behind barrier conditions (Coleman et at., 1977) at the Charles River Breeding ... homogenates of Fischer 344 strain rats. Samples of renal tissues were homogenized in a solution containing 5 p. 100 La -! 25 p. 100 H3.N0 The samples were digested, centrifuged and assayed by atomic absorption

Comparing the Behavioural Effects of Exogenous Growth Hormone and Melatonin in Young and Old Wistar Rats

subjects. The present report aims at discerning the eventual difference between cognitive and motor effects of the two hormones when administered to young and aged Wistar rats. The effects were tested in the ... , no. 1, pp. 43–48, 1984. View at Publisher · View at Google Scholar · View at ScopusA. Rex, J.-P. Voigt, and H. Fink, “Behavioral and neurochemical differences between Fischer 344 and Harlan- Wistar

Social partnering alters sleep in fear-conditioned Wistar rats

period with a naive conspecific would improve sleep architecture in response to cued fear conditioning in Wistar rats. Rats were randomly assigned to either the socially isolated or socially partnered ... Sprague-Dawley and Long-Evans rats, the Wistar (WIS) rat strain is less sensitive to danger cues, and was found to be more mobile in a swim test when the water was soiled with urine and feces of swim

Early-onset behavioral and neurochemical deficits in the genetic mouse model of phenylketonuria

), the genetic murine model of PKU. To date, adult behavioral and neurochemical alterations have been mainly investigated in ENU2 mice, whereas there are no clear indications about the onset of these ... comprehensive behavioral and neurochemical assay of the developing ENU2 mice. Overall, our findings demonstrate that ENU2 mice are significantly smaller than WT until pnd 24, present a significant delay in the

Electrocardiogram Delineation in a Wistar Rat Experimental Model

waves delineation in Wistar rats applying WT. We also describe the ECG signal of the Wistar rats giving the characteristics of its spectrum among other useful information. Methods. We evaluated a ... analyses using Wistar rats. 1. Introduction Electrocardiograms (ECGs) are broadly used for diagnosing many cardiac pathologies as well as for researching on experimental animals. Since physiological

Patterns of motor activity in spontaneously hypertensive rats compared to Wistar Kyoto rats

study, we wanted to use linear and non-linear methods to explore differences in motor activity patterns in SHR/NCrl rats compared to Wistar Kyoto (WKY/NHsd) rats. Methods A total number of 42 rats (23 SHR ... analyzed videorecorded motor behavior of SHR/NCrl rats in order to look for differences in behavioral organization between this strain and control rats of the WKY/NHsd strain. In addition to total activity

Sex-based differences in phagocyte metabolic profile in rats with monosodium glutamate-induced obesity

reactivity are characterized by sex-associated differences. The aim of the work was a comparative investigation of metabolic profiles of phagocytes from different locations in male and female rats with MSG ... with MSG-induced obesity. The administration of monosodium glutamate (MSG) caused obesity, with sex-associated differences, that was more severe in male rats. Obesity was associated with pro-inflammatory

Concentration-related metabolic rate and behavioral thermoregulatory adaptations to serial administrations of nitrous oxide in rats

% causes rats to select cooler ambient temperatures both during initial administrations and during subsequent administrations in which the hyperthermic state exists. Thus, an available behavioral response ... behavioral temperature preference, locomotion and core temperature. Materials and methods Subjects and ethics approval Male Long-Evans rats (Charles River, N = 72, ~21 d of age upon arrival) were maintained

Antidepressant-Like Effect of the Endogenous Neuroprotective Amine, 1MeTIQ in Clonidine-Induced Depression: Behavioral and Neurochemical Studies in Rats

clonidine in the behavioral and neurochemical tests carried out in rats. The behavioral study has shown that clonidine produced depression in the locomotor activity test but did not cause pro-depressive ... locomotor activity test was used to check motor function of rats in the clonidine model of depression. In the second part of the study, in addition to the behavioral tests, we also carried out neurochemical

Effect of Chromolaena Odorata on Hepatotoxicology and Histopathology in the Liver Induced by Salmonella Typhi in Wistar Rats

study attempts to investigate the Hepatotoxicological and Histopathological changes of the liver associated with Salmonella typhi infection in Wistar rats and to examine the potential of methanol leaf ... error of mean. Differences between means were assessed using Analysis of variance (ANOVA) and post test using LSD multiple comparison test (Mead & Curnow, 1982). Results Exposure of Wistar rats to a

Effects of Aging and Tocotrienol-Rich Fraction Supplementation on Brain Arginine Metabolism in Rats

supplementation in the form of tocotrienol-rich fraction (TRF) on brain arginine metabolism. Male Wistar rats at ages of 3 and 21 months were supplemented with TRF orally for 3 months prior to the dissection of ... memory, respectively. Therefore, the current study further analyzed the behavioral performance data in relation to the neurochemical level in the rats’ brain, to further explore the effects of age on

Validated UPLC-MS/MS method for the quantification of dasatinib in plasma: Application to pharmacokinetic interaction studies with nutraceuticals in Wistar rats

studying the possibility of PK interaction between DAS and the selected nutraceuticals in UC rats using UPLC- MS/MS. Chromatographic analysis was carried out using BEH C 18 column (Waters) with a mobile ... the local Research Ethics committee, King Saud University. Application to pharmacokinetic studies Wistar healthy male rats weighing 250 ± 30 g were provided by the animal house, Women Student-Medical

Neurochemical and Neurotoxic Effects of MDMA (Ecstasy) and Caffeine After Chronic Combined Administration in Mice

proenkephalin were determined by quantitative PCR reactions. The behavioral changes were measured by the open-field (OF) test and novel object recognition (NOR) test. Caffeine potentiated MDMA-induced DA release ... Reveron ME , Maier EY , Duvauchelle CL ( 2010 ) Behavioral, thermal and neurochemical effects of acute and chronic 3,4- methylenedioxymethamphetamine (ecstasy) self-administration . Behav Brain Res 2007

Effects of energy drinks on biochemical and sperm parameters in Wistar rats

Background The present study evaluates the effects of energy drinks on the reproductive and biochemical parameters of adult male rats. Methods A total of 40 male rats (Wistar) were exposed to an ... , cardiac, and renal functions, as well as on sperm parameters of male Wistar rats. The biochemical markers in blood serum for the above functions and testosterone will be analyzed, together with the sperm

Nephroprotective Effect of Sonchus oleraceus Extract against Kidney Injury Induced by Ischemia-Reperfusion in Wistar Rats

-inflammatory activities; however, its effects on renal I/R are unknown. Objective. To evaluate whether S. oleraceus extract (S.O.e.) has nephroprotective activity in an I/R model in Wistar rats. Materials and ... the current investigation was to evaluate whether S. oleraceus has a nephroprotective effect against I/R-induced injury in Wistar rats. 2. Material and Methods2.1. Extract Preparation The plant was

Individual differences in response to alcohol exposure in zebrafish (Danio rerio)

differences and behavioral changes due to alcohol exposure in zebrafish (Danio rerio). To that end, adult animals were separated into two behavioral profiles: bold and shy, according to their risk taking ... voluntary alcohol intake on behavioral profiles in outbred Wistar rats . Behav Brain Res . Elsevier B.V. ; 2014 ; 275 : 288 ± 296 . 2014 . 08 .058 5. Zarkin GA , Cowell AJ