metabolically evaluated using Viametrics-E (Molecular Biometrics, USA) and ranked on the day of embryo transfer. 10μl of media samples of each corresponding embryo were loaded onto specialized spectrometer
competing risks data . Biometrics 2014 ; 70 : 1 - 9 . Jeong J-H , Fine JP . Parametric regression on cumulative incidence function . Biometrics 2007 ; 8 : 184 - 196 . Kavanaugh ML , Schwarz EB . Prospective
. Sample-size formula for the proportional-hazards regression model . Biometrics 1983 ; 39 : 499 - 503 . Skakkebaek NE , Rajpert-De Meyts E , Buck Louis GM , Toppari J , Andersson AM , Eisenberg ML , Jensen ... cancer among infertile men . Cancer 2010 ; 116 : 2140 - 2147 . Williams RL . A note on robust variance estimation for cluster-correlated data . Biometrics 2000 ; 56 : 645 - 646 . Wohlfahrt-Veje C , Main KM
, underdogs or biometrics? Asian J Androl 2010 ; 12 : 36 - 46 . Auger J , Jouannet P , Eustache F . Another look at human sperm morphology . Hum Reprod 2016 ; 31 : 10 - 23 . Bellastella G , Cooper TG
PubMed WorldCat Weinberg CR , Gladen BC , Wilcox AJ . Models relating the timing of intercourse to the probability of conception and the sex of the baby . Biometrics 1994
spectroscopy system (Molecular Biometrics Inc., Norwood, MA, USA) intended for IVF use was used to analyze the spent embryo culture media on Day 3 for the treatment group. The spectrometer was checked daily for ... algorithm developed using the NIR spectra with a known pregnancy outcome of transferred Day 3 embryos. This algorithm was developed using proprietary methodology of Molecular Biometrics Inc. entailing a
group, all GQE on Day 2 or Day 5 were analysed using a prototype NIR spectroscopy system intended for IVF use (Molecular Biometrics Inc., Norwood, MA, USA). From the two or more GQE randomized to the NIR ... group, a small aliquot (13 ml) was aspirated from the culture medium droplet of each GQE and injected into a sample cell (Molecular Biometrics Inc.) for analysis by the instrument. A sample cell was only
cleavage score were used for embryo selection. NIR spectroscopy method A prototype NIR spectroscopy system (Molecular Biometrics Inc., Norwood, MA, USA) intended for IVF use was used to analyze the spent ... using proprietary methodology of Molecular Biometrics Inc. entailing a modification of previous publications (Vergouw et al., 2008; Seli et al., 2010a; Hardarson et al., 2012) . End-points, inclusion
embryo culture and/or grading systems. NIR spectroscopy In the NIR group, all GQE on Day 2 or Day 5 were analysed using a prototype NIR spectroscopy system intended for IVF use (Molecular Biometrics Inc ... Biometrics Inc.) for analysis by the instrument. A sample cell was only used for one embryo and then discarded. The instrument used the NIR spectroscopic technology as previously described (Seli et al., 2007
logistic regression model with random effects . Biometrics 2000 ; 56 : 909 - 914 . Magli MC , Gianaroli L , Ferrareti AP . Chromosomal abnormalities in embryos . Mol Cell Endocrinol 2001 ; 22 : S29 - S34
-wide association study link novel loci to endometriosis . PLoS One 2013 ; 8 : e58257 . Barlow WE . Robust variance estimation for the case-cohort design . Biometrics 1994 ; 50 : 1064 - 1072 . Blaschuk O ... estimation for cluster-correlated data . Biometrics 2000 ; 56 : 645 - 646 . Williams AL , Patterson N , Glessner J , Hakonarson H , Reich D. Phasing of many thousands of genotyped samples . Am J Hum Genet 2012
2010 ; 94 : 2631 - 2635 . Quan H , Shih WJ . Assessing reproducibility by the within-subject coefficient of variation with random effects models . Biometrics 1996 ; 52 : 1195 - 1203 . Rylander L
. A Bayesian approach to joint modeling of menstrual cycle length and fecundity . Biometrics 2016 ; 72 : 193 – 203 . Google Scholar Crossref Search ADS PubMed Olsen J
to comparative fecundability studies . Biometrics 1986 ; 42 : 547 - 60 .
. J Stat Plan Infer 2000 ; 91 : 295 - 312 . Weinberg CR , Gladen BC . The beta-geometric distribution applied to comparative fecundability studies . Biometrics 1986 ; 42 : 547 - 560 . World Health
- 1838 . Pocock SJ . Allocation of patients to treatment in clinical trials . Biometrics 1979 ; 35 : 183 - 197 . Roberts C , Torgerson DJ . Understanding controlled trials: baseline imbalance in randomised
- 1838 . Pocock SJ . Allocation of patients to treatment in clinical trials . Biometrics 1979 ; 35 : 183 - 197 . Roberts C , Torgerson DJ . Understanding controlled trials: baseline imbalance in randomised
. Dunson DB , Weinberg CR . Modeling human fertility in the presence of measurement error . Biometrics 2000 ; 56 : 288 - 292 . Dunson DB , Baird DD , Wilcox AJ , Weinberg CR . Day-specific probabilities of ... pregnancy . Br Med J 1973 ; 4 : 28 - 31 . Royston JP . Basal body temperature, ovulation and the risk of conception, with special reference to the lifetimes of sperm and egg . Biometrics 1982 ; 38 : 397 - 406
Steril 2015 ; 103 : 323 - 332 . Landis JR , Koch GG . The measurement of observer agreement for categorical data . Biometrics 1977 ; 33 : 159 - 174 . Mangalraj AM , Muthukumar K , Aleyamma T , Kamath MS
no funding relevant to this study. Conflict of interest None declared. Begg CB , Mazumdar M. Operating characteristics of a rank correlation test for publication bias . Biometrics 1994 ; 50 : 1088
