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Nonsense-mediated mRNA decay: a ‘nonsense’ pathway makes sense in stem cell biology

. Transcriptional regulations and epigenetic modulations have been extensively implicated in stem cell biology. However, post-transcriptional regulatory mechanisms, such as NMD, in stem cell regulation are largely ... embryonic stem cell self-renewal and differentiation The embryonic stem cell (ESC) is an important model to study the fundamental mechanisms of developmental biology ( 88,89 ). The establishment of ESC

Correction to: New Advances in Human X Chromosome Status from a Developmental and Stem Cell Biology

Department of Genetics, Yale Stem Cell Center, Yale School of Medicine , New Haven, CT 06520 , USA - Unfortunately, Acknowledgements section was missing in the originally published article. It is now

Applying Data Analytics and Visualization to Assessing the Research Impact of the Cancer Cell Biology (CCB) Program at the University of North Carolina at Chapel Hill

-CH) for the Cancer Cell Biology (CCB) program in the institution’s cancer center through bibliometric data analysis and visualization. Methods: A total of 642 publications produced by the CCB ... center programs as an example of the IMV services that HSL provides. The Cancer Cell Biology (CCB) Program at the UNC Lineberger Comprehensive Cancer Center has been dedicated to the study of cancer

Science Academies’ Refresher Course on Experimental Approaches to Molecular Microbiology and Cell Biology

and Cell Biology' for graduate and postgraduate college/university teachers will be held at School of Life Sciences, Manipal University, Manipal for two weeks from 20th November to 2nd December 2017 ... . The objective of this Course is intended to impart teaching methodologies and to familiarize with advanced topics in microbiology and cell biology. A variety of teaching methods such as lectures

Recent topics in kidney research: morphology and molecular cell biology

morphology and cell biology of the kidney, including contributions from among the most active researchers in this field. The kidney is a vital organ in the human body and is one of the most complicated organs ... biology of mesangial cells: the third cell that maintains the glomerular capillary . Anat Sci Int 92 (in press) Ludwig C ( 1852 -1856) Lehrbuch der Physiologie des Menschen. In two volumes . Winter

Journal of Membrane Biology: Cell Biology Section

that quantitative studies integrating information from multiple disciplines are fundamental to advancing the field of membrane biology. Techniques such as lipidomics, organelle isolation, and high

Single-cell sequencing in stem cell biology

Cell-to-cell variation and heterogeneity are fundamental and intrinsic characteristics of stem cell populations, but these differences are masked when bulk cells are used for omic analysis. Single ... for the relevant papers not cited here due to strict space limitation. 1. Junker JP , van Oudenaarden A. Every cell is special: genome-wide studies add a new dimension to single-cell biology . Cell

In focus in HCB: Hard Tissue Biology

Cell Biology, focuses on the bone, cartilage, and teeth in mammals. Bone metabolism is not only strictly regulated by cellular events, local factors, mechanical stress, gender, age, and the hormonal ... the ultrastructure and cell biology of matrix vesicles-mediated mineralization, by introducing her own and other researchers’ evidence. Among many osteotropic/ calcitropic hormones, an active form, 1,25

Life versus ‘biomass’—why application needs cell biology

, were invoked to explain life. This molecular explanation of life not only shifted biology into the centre of scientific progress but also stimulated a vigorously developing new branch of technological ... application. The success of biotechnology demonstrated impressively that tools and concepts derived from chemistry could be employed to manipulate biology. Interestingly, over the entire first half of the last

Safety, security, and serving the public interest in synthetic biology

This article describes what may be done by scientists and by the biotechnology industry, generally, to address the safety and security challenges in synthetic biology. Given the technical expertise ... well as the importance of these issues to the future of the industry, scientists who work in synthetic biology should be informed about these challenges and get involved in shaping policies relevant to

Lung bioengineering: physical stimuli and stem/progenitor cell biology interplay towards biofabricating a functional organ

this approach is how to drive stem cell differentiation onto the different lung cell phenotypes. Whereas the use of soluble factors as agents to modulate the fate of stem cells was established from an ... across the organ. The present review focuses on describing how the cell mechanical microenvironment can modulate stem cell differentiation and how these stimuli could be incorporated into lung bioreactors

In focus in HCB: from cell biology to tissue structure and function

Histochemistry and Cell Biology presents Reviews and Original Articles with which members of the Editorial Board and former coworkers would like to express their sincere appreciation of Detlev Drenckhahn’s ... contribution to the superior quality of Histochemistry and Cell Biology during his time as Co-Editor-in-Chief. Shortly before taking up this position, Detlev Drenckhahn had moved his group from Marburg to

Calcific Aortic Valve Disease: a Developmental Biology Perspective

morphogenetic protein (BMP) . Anat Rec . 2000 ; 258 ( 2 ): 119 - 27 . 33. Person AD , Klewer SE , Runyan RB . Cell biology of cardiac cushion development . Int Rev Cytol . 2005 ; 243 : 287 - 335 . 34. Liebner S ... mechanistic-based therapies beyond surgical intervention to improve patient outcome. This article is part of the Topical Collection on Regenerative Medicine Heart valve; Calcification; Valvulogenesis; Cell

Skin appendage-derived stem cells: cell biology and potential for wound repair

to General Hospital of PLA , 51 Fu Cheng Road, Beijing 100048 , People's Republic of China 4 Wound Healing and Cell Biology Laboratory, Institute of Basic Medical Sciences, General Hospital of PLA ... on optimizing the available therapy in cutaneous repair and regeneration. Skin appendages; Stem cells; Cell biology; Wound healing - Background Skin as a barrier for resisting external invasion is

Glial cell biology in the Great Lakes region

cell biology. The array of functions that glial cells (astrocytes, microglia, oligodendrocytes, Schwann cells) play in health and disease is constantly increasing. Despite this diversity, GLG meetings ... Department Anesthesiology, University of Illinois-Chicago , Chicago, IL 60612 , USA 2 Department Cell Biology and Anatomy, Wayne State University , Detroit, MI 48202 , USA We report on the tenth bi-annual

Editorial: Cell biology in agriculture and food sciences

sciences. Present issue of the protoplasma is also focused on the cell biology of agriculture and food sciences based on an international conference on agriculture and biological sciences organized during ... arabidopsis thaliana during impaired chloroplast development . Protoplasma. doi:10 .1007/s00709-016-0958-y Romanova AK , Semenova GA , Ignatev AR , Novichkova NS , Fomina IR ( 2016 ) Biochemistry and cell

The biogenesis of iron–sulfur proteins: from cellular biology to molecular aspects

fantastic playground for gathering together genetics, cell biology, integrated structural biology, metalloproteomics, and spectroscopy to form a unique research platform that provides a molecular view of Fe–S ... Kostas Tokatlidis and colleagues, from the Institute of Molecular, Cell and System Biology of the University of Glasgow, review, from chemistry to disease, the recent discoveries in both the yeast and

The CRISPR/Cas9 system sheds new lights on the biology of protozoan parasites

Biology, Institute of Genetics and Animal Breeding PAS , Postepu 36A, 05-552 Jastrzebiec , Poland 5 Faculty of Biology, Animal Sciences and Bioeconomy, University of Life Sciences in Lublin , Akademicka 13

New future of cell biology and toxicology: thinking deeper

- The combination of cell biology and toxicology (CBTo) demonstrates the potential effects of elements in cellular structures, organelles, functioning properties, metabolic circles, signaling pathways, or ... , medical, occupational, and regulatory toxicology. Thus, future issues of the journal will focus on clinical and translational research with an emphasis on molecular and cell biology, genetic and epigenetic

Virtual Reconstruction and Three-Dimensional Printing of Blood Cells as a Tool in Cell Biology Education

The cell biology discipline constitutes a highly dynamic field whose concepts take a long time to be incorporated into the educational system, especially in developing countries. Amongst the main ... obstacles to the introduction of new cell biology concepts to students is their general lack of identification with most teaching methods. The introduction of elaborated figures, movies and animations to