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Calcific Aortic Valve Disease: a Developmental Biology Perspective

valve disease (CAVD) with a focus on the contribution of developmental programs. Recent Findings Calcification of the aortic valve is an active process characterized by calcific nodule formation on the ... , these valves, unlike the semilunar valves, receive WT1-positive cells derived from the adjacent epicardium [62]. While these developmental studies are informative, the field has yet to delineate the

The Confluence of Philosophy And Biology: An Excavation of Philosophical Issues in Molecular and Developmental Biology

Philosophical evaluations have played an influential role in the growth and development of molecular and developmental biology to ensure that every individual is born healthy, born wanted and has the ... solve them. This challenge gave birth to a philosophical excavation of molecular and developmental biology. This paper is an attempt to expose that philosophy is a major tool in proffering possible

The Renaissance of Developmental Biology

Since its heyday in the 1980s and 90s, the field of developmental biology has gone into decline; in part because it has been eclipsed by the rise of genomics and stem cell biology, and in part ... genome editing, have created the conditions for the renaissance of a new wave of developmental biology with greater translational relevance. This Essay is part of the "Where Next?" Series - It is a

Bioinformatics approaches to single-cell analysis in developmental biology

analysis is especially important in developmental biology as subtle spatial and temporal differences in cells have significant associations with cell fate decisions during differentiation and with the ... omics techniques on single cells. There have been improvements in computational single-cell image analysis in developmental biology regarding feature extraction, segmentation, image enhancement and

Evidence for Karyotype Polymorphism in the Free-Living Flatworm, Macrostomum lignano, a Model Organism for Evolutionary and Developmental Biology

Over the past decade, the free-living flatworm Macrostomum lignano has been successfully used in many areas of biology, including embryology, stem cells, sexual selection, bioadhesion and aging. The

Developmental auditory exposure shapes responses of catecholaminergic neurons to socially-modulated song

Developmental sensory experience is critical to the tuning of sensory systems and can shape perceptual abilities and their neural substrates. Neuromodulators, including catecholamines, contribute to ... developmental sensory experience has lasting effects on the neuromodulatory neurons themselves. Here, we used female zebra finches to investigate the degree to which developmental auditory experience can have

ANISEED 2015: a digital framework for the comparative developmental biology of ascidians

information system in the field of ascidian developmental biology. This article reports the development of the system since its initial publication in 2010. Over the past five years, we refactored the system ... Developmental Biology Laboratory, Department of Biological Sciences, School of Science and Engineering, Tokyo Metropolitan University , 1-1 Minamioosawa, Hachiooji, Tokyo 192-0397 , Japan 6 Department of

ANISEED 2015: a digital framework for the comparative developmental biology of ascidians

Developmental Biology Laboratory, Department of Biological Sciences, School of Science and Engineering, Tokyo Metropolitan University , 1-1 Minamioosawa, Hachiooji, Tokyo 192-0397 , Japan 6 Department of ... l'Evolution de Montpellier (ISE-M), UMR 5554 CNRS-IRD-Universite ́ de Montpellier , F-34090 Montpellier , France 15 Center for Developmental Genetics, Department of Biology, New York University , New York, NY

Attention sports fans! The far-reaching contributions of bud sport mutants to horticulture and plant biology

molecular or cytological changes causing the phenotype have been identified. Analysis of these sports has provided valuable insight into developmental processes, gene function and regulation, and in some ... phenotypes and illustrate the developmental plasticity of the tendril52. A somatic variant of Carignan has a reiterated reproductive meristem (RRM) phenotype, leading to large, highly branched fruit clusters

How to Grow a Lung: Applying Principles of Developmental Biology to Generate Lung Lineages from Human Pluripotent Stem Cells

48109 , USA 6 Department of Cell and Developmental Biology, University of Michigan Medical School , Ann Arbor, Michigan 48109 , USA The number and severity of diseases affecting human lung development ... generating lung tissue in vitro [35•, 36•, 37•, 38•, 39•, 40•, 41•, 42•, 43•, 44•, 45•]. In this review article, we will introduce the developmental biology framework that forms the basis used by many groups

Rudolf Weber (1922–2015): a driving force in the transition of developmental biology into a molecular and cellular science

and Fritz Erich Lehmann, he became the third in a line of outstanding developmental biologists at the University of Bern, Switzerland. Throughout his career, he helped shape modern developmental biology ... (Entwicklungsphysiologie), the term used for the research field of developmental biology at the time. A native of Bern, Baltzer had studied with Theodor Boveri in Würzburg (Germany) and with Hans Spemann in Freiburg im

Crossing the Threshold to Deeper Developmental Biology

Developmental Biolog y Gregory K . Davis 0 1 0 Bryn Mawr College 1 Gregory K. Davis, Assistant Professor, Biology Department, Bryn Mawr College Follow this and additional works at: http ... ://repository.brynmawr.edu/tlthe - CROSSING THE THRESHOLD TO DEEPER DEVELOPMENTAL BIOLOGY I sometimes encounter a peculiar mix in my undergraduate course in developmental biology. A student is able, flawlessly, to recite

Science Academies’ Refresher Course in Developmental Biology 16–28 November 2015

'Developmental Biology' for graduate and postgraduate teachers will be held at the National Institute for Research in Reproductive Health, Mumbai for a period of two weeks, from 16th to 28th November 2015. The ... objectives of this Refresher Course are to update the participants about the advances in the field of Developmental Biology; various small animal models used and give hands-on training on some modern

Comparative Biology of Cycad Pollen, Seed and Tissue - A Plant Conservation Perspective

improve their protection is long-standing. We contend that progress in this direction will not be made until there is better understanding of cycad pollen, seed and tissue biology, which at the moment is ... , & K. Norstog. 1992a. Somatic embryogenesis from leaf callus of mature plants of the gymnosperm Ceratozamia mexicana var. robusta (Miq.) dyer (Cycadales) . In vitro Cell Developmental Biology 28 : 59

Placenta Accreta Spectrum: A Review of Pathology, Molecular Biology, and Biomarkers

underlying molecular biology of PAS is a complex process that requires further research; for ease, we have divided these processes into angiogenesis, proliferation, and inflammation/invasion. A number of ... the molecular biology of PAS, and additional biomarkers are needed to aid diagnosis and disease stratification. 1. Introduction Placenta accreta was first described in 1937 by Irving et al. as failure

In focus in HCB: Hard Tissue Biology

, Shitsukawa, Toon, Ehime 791-0295 , Japan 1 Developmental Biology of Hard Tissue, Graduate School of Dental Medicine and Faculty of Dental Medicine, Hokkaido University , Sapporo, Hokkaido 060-8586 , Japan 2 ... Sohei Kitazawa Vol.:(011233456789) - Among the varieties of biological mineralization in nature, e.g., shell, coral, and bone, this special issue “Hard Tissue Biology” presented by Histochemistry and

Evolutionary crossroads in developmental biology

, molecular and genomic resources that have been generated over the years by large communities of scientists. However, the field of developmental biology has a long and colourful history of experimentation with ... stretches back through the entire history of developmental biology. The important evolutionary insight that they provide has long been recognised; Charles Darwin even devotes an entire chapter of The Origin