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Calcific Aortic Valve Disease: a Developmental Biology Perspective

valve disease (CAVD) with a focus on the contribution of developmental programs. Recent Findings Calcification of the aortic valve is an active process characterized by calcific nodule formation on the ... , these valves, unlike the semilunar valves, receive WT1-positive cells derived from the adjacent epicardium [62]. While these developmental studies are informative, the field has yet to delineate the

The Confluence of Philosophy And Biology: An Excavation of Philosophical Issues in Molecular and Developmental Biology

Philosophical evaluations have played an influential role in the growth and development of molecular and developmental biology to ensure that every individual is born healthy, born wanted and has the ... solve them. This challenge gave birth to a philosophical excavation of molecular and developmental biology. This paper is an attempt to expose that philosophy is a major tool in proffering possible

The Renaissance of Developmental Biology

Since its heyday in the 1980s and 90s, the field of developmental biology has gone into decline; in part because it has been eclipsed by the rise of genomics and stem cell biology, and in part ... genome editing, have created the conditions for the renaissance of a new wave of developmental biology with greater translational relevance. This Essay is part of the "Where Next?" Series - It is a

Bioinformatics approaches to single-cell analysis in developmental biology

analysis is especially important in developmental biology as subtle spatial and temporal differences in cells have significant associations with cell fate decisions during differentiation and with the ... omics techniques on single cells. There have been improvements in computational single-cell image analysis in developmental biology regarding feature extraction, segmentation, image enhancement and

Evidence for Karyotype Polymorphism in the Free-Living Flatworm, Macrostomum lignano, a Model Organism for Evolutionary and Developmental Biology

Over the past decade, the free-living flatworm Macrostomum lignano has been successfully used in many areas of biology, including embryology, stem cells, sexual selection, bioadhesion and aging. The

Biology, Art and Sustainability

How can the teaching of biology contribute to sustainability education? The authors of this article suggest that their approach has the potential to increase the students’ level of engagement with ... approach in which drawing and painting are integral parts of the biology lesson. The start occurred when a biology teacher asked an art teacher for assistance for an excursion in botany. The biology teacher

ANISEED 2015: a digital framework for the comparative developmental biology of ascidians

information system in the field of ascidian developmental biology. This article reports the development of the system since its initial publication in 2010. Over the past five years, we refactored the system ... Developmental Biology Laboratory, Department of Biological Sciences, School of Science and Engineering, Tokyo Metropolitan University , 1-1 Minamioosawa, Hachiooji, Tokyo 192-0397 , Japan 6 Department of

How to Grow a Lung: Applying Principles of Developmental Biology to Generate Lung Lineages from Human Pluripotent Stem Cells

48109 , USA 6 Department of Cell and Developmental Biology, University of Michigan Medical School , Ann Arbor, Michigan 48109 , USA The number and severity of diseases affecting human lung development ... generating lung tissue in vitro [35•, 36•, 37•, 38•, 39•, 40•, 41•, 42•, 43•, 44•, 45•]. In this review article, we will introduce the developmental biology framework that forms the basis used by many groups

A tribute to Dr. Gordon Hisashi Sato (December 24, 1927–March 31, 2017)

Gordon H. Sato, an innovator in mammalian tissue culture and integrated cellular physiology, passed away in 2017. In tribute to Dr. Sato, In Vitro Cellular and Developmental Biology—Animal presents a ... Developmental Biology (1987-1991), and the recipient of the lifetime achievement award from the Society for In Vitro Biology (2002). He was elected to the US National Academy of Sciences in 1984. Tissue culture

Effect of developmental NMDAR antagonism with CGP 39551 on aspartame-induced hypothalamic and adrenal gene expression

aspects of behavior and spatial cognition, and that this can be modulated by developmental N-methyl-D-aspartate receptor (NMDAR) blockade with the competitive antagonist CGP 39551 (CGP). Since glucose ... ±5. 2001 .3255 PMID: 11749047 45. Tourian A , Treiman DM , Carr JS . Developmental biology of hepatic phenylalanine hydroxylase activity in foetal and neonatal rats

Rudolf Weber (1922–2015): a driving force in the transition of developmental biology into a molecular and cellular science

and Fritz Erich Lehmann, he became the third in a line of outstanding developmental biologists at the University of Bern, Switzerland. Throughout his career, he helped shape modern developmental biology ... (Entwicklungsphysiologie), the term used for the research field of developmental biology at the time. A native of Bern, Baltzer had studied with Theodor Boveri in Würzburg (Germany) and with Hans Spemann in Freiburg im

Literary Digest: Cannibal Poetry and Biology

A humanities professor and a biology professor at Wilbur Wright College collaborated to create a lesson on human digestion and poetry, enriching the humanities course theme on cannibalism. This ... biology for the past 22 years at Wilbur Wright College and currently serves as the department's chairperson. She founded the college's Center for Teaching & Learning. Claire Boeck has been teaching

Developmental profiling of microRNAs in the human embryonic inner ear

), and otic vesicle (OV) from paraffin embedded (FFPE) human specimens in the Carnegie developmental stages 13–15. We found that in human embryonic tissues, there are different patterns of miRNA expression ... miRNA expression in the CVG, NC and OV. In particular, members of the miR-183 family (miR-96, miR-182, and miR-183) are differentially expressed in the CVG compared to NC and OV at Carnegie developmental

Science Academies’ Refresher Course in Developmental Biology 16–28 November 2015

'Developmental Biology' for graduate and postgraduate teachers will be held at the National Institute for Research in Reproductive Health, Mumbai for a period of two weeks, from 16th to 28th November 2015. The ... objectives of this Refresher Course are to update the participants about the advances in the field of Developmental Biology; various small animal models used and give hands-on training on some modern

Crossing the Threshold to Deeper Developmental Biology

Developmental Biolog y Gregory K . Davis 0 1 0 Bryn Mawr College 1 Gregory K. Davis, Assistant Professor, Biology Department, Bryn Mawr College Follow this and additional works at: http ... :// - CROSSING THE THRESHOLD TO DEEPER DEVELOPMENTAL BIOLOGY I sometimes encounter a peculiar mix in my undergraduate course in developmental biology. A student is able, flawlessly, to recite

Alcohol Text Messages: A Developmental Study

on paternal bonding, sleep deprivation, developmental problems, behavioural issues and FASD. Participants repeatedly stated they thought messages that directly connected the father’s behaviour with ... indicated that they would access information if it were directly linked to fatherhood and developmental concerns. For example, as noted by Darren: I like the ones that link the fathers to the kids in

Introduction: Eric Davidson and the molecular biology of evolution and development

the workshop and examine the importance of genomes and gene regulatory networks in extant biology, developmental biology, evolutionary biology and medicine, as well as a collection of remembrances of ... are also discussed. Developmental biology; Evolutionary biology network; Genome; Molecular medicine; Gene regulatory - Loeb Centre that had already explored the recent transformations of biology