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Genetic interactions between the chromosome axis-associated protein Hop1 and homologous recombination determinants in <Emphasis Type=

-type levels of meiotic recombination and localization to meiotic chromatin. Furthermore, we show that hop1∆ only weakly interacts genetically with mutants of homologous recombination factors, and in ... fully functional recombination machinery to produce viable progeny. Discussion Here, we characterize the genetic interactions of hop1, which encodes a meiotic HORMA domain protein, with homologous

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in the pathogenesis of AML [ 2 ]. Moreover, genetic abnormalities such as chromosome aberrations and gene mutations were also seen as the most powerful prognostic information [ 3 ]. Despite recent ... downstream gene ID2 in AML As is well-known, lncRNAs function directly or indirectly through the protein-encoding gene. A previous study showed that H19 was positively associated with ID2 expression in

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Genetic influences modulating executive functions engaging prefrontal cortical brain systems were investigated in 141 male subjects. The effects of variations in two genes implicated in dopamine and ... to the etiology of schizophrenia is considerable, and recent molecular genetic studies indicate that several genes may be associated with the disorder. In an endeavor to expose susceptibility genes

Improvement of <Emphasis Type=

Center of Industrial Culture Collection (CICC) with the registration number of CICC 20935. The homologous sacB recombination system was used to introduce modulations into the chromosome as described ... pK18mobsacB. All of the recombinant plasmids were transformed into C. glutamicum cells by electroporation. After two rounds of homologous recombination, engineered C. glutamicum with the corresponding

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Mutations in IDH1/2 genes are a marker of good prognosis for glioma patients, associated with low grade gliomas and secondary glioblastomas. Immunohistochemistry and Sanger sequencing are current ... staining or regional heterogeneity of mIDH1-R132H protein expression is present and in these cases the confirmatory genetic testing may be necessary [ 23, 29 ]. We restrain from final conclusion about

Transcriptome profiling of <Emphasis Type=

HSP70, and also genes associated with the ubiquitin–proteasome proteolytic pathway suggests that ethanol stress may cause aggregation of misfolded proteins. Finally, ethanol stress in I. orientalis ... Kane 2008) . Similar mechanisms in I. orientalis may help I. orientalis maintain pH stability in the presence of ethanol. HSP90, HSP70, and ubiquitin Genes associated with protein folding and

Effect of <Emphasis Type=

trait from new plant type cultivars into recipient lines has also been initiated to broaden the genetic background of the NPT germplasm and refine the original ideotype design for increasing grain filling ... ; Takai et al. 2013; Zhang et al. 2014) . The role of overexpressed gene (LOC_Os04g52590) coding for protein kinase domain-containing protein in qGN4.1 QTL-NILs is being further investigated by genetic

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exposed to natural selection for survival under heavy mite infestation rates (Locke 2016). The best studied population is a population on Gotland, Sweden, for which the genetic basis of this adaptation has ... foulbrood, it has been proposed to be based on a two-locus genetic model with one locus for uncapping the brood and one locus responsible for removing diseased brood (Rothenbuhler 1964). However, this model

The presynaptic machinery at the synapse of <Emphasis Type=

Synapses are specialized contact sites that mediate information flow between neurons and their targets. Important physical interactions across the synapse are mediated by synaptic adhesion molecules ... key synaptic determinants, optogenetics coupled with high-pressure freezing to resolve the relationship between docking and fusion (Watanabe et  al. 2013) and genetic manipulation of syntaxin to

A series of new <Emphasis Type=

of the most useful hyperthermophilic model species, not least due to its natural competence and genetic tractability. Despite this, the range of genetic tools available for T. kodakarensis remains ... shuttle vectors. Phylogenetic analysis of the replication-associated protein encoded by pTN1 reveals it to be part of a small family of homologous genes encoded by other Thermococcales plasmids (Fig. 1

Genomic insights of aromatic hydrocarbon degrading <Emphasis Type=

study of physiological and genetic background of the metabolic capability associated with pollutant degradation. Moreover, many complete and draft genome sequences relevant to biodegradation have been ... the total number of protein-coding genes in the annotated genome Degradation of PAH by AWD5 and its genetic elements Klebsiella pneumoniae AWD5 was found to degrade pyrene (56.9%), chrysene (36.5

Genotyping of <Emphasis Type=

the genome of the cultured bacterium has made it possible to fulfill the minimal standards for genetic characterization of species within the order Chlamydiales. The complete rRNA genes, the amino acid ... approach that combines phenotypic and genetic characteristics. However, unlike other orders of bacteria there are a high number of Candidatus species described as members of Chlamydiales due to the lack of

First report of <Emphasis Type=

, along with two groups formed as a result of recombination events between members of the plum- and the citrus-type (P-C group), or of the plum- and hop-type, or cit3 sequence variant (P-H/cit3 group). In ... Ampelopsis heterophylla. These HSVd isolates along with others from V. vinifera and V. labrusca were phylogenetically analyzed. Next generation sequencing; HSVd; Incidence; Genetic variability; Vitis

Epigenetic modifications in <Emphasis Type=

are not individually associated with NSCLC survival, which indicates that there may have interactions of KDM4 and the other elements. A major strength of this study is that we used weighted random ... , Kamat AM , Huang M , Grossman HB , Dinney CP , Lerner SP , Wu X , Gu J . High-order interactions among genetic polymorphisms in nucleotide excision repair pathway genes and smoking in modulating bladder

ZNF830 mediates cancer chemoresistance through promoting homologous-recombination repair

Homologous recombination (HR), which mediates the repair of DNA double-strand breaks (DSB), is crucial for maintaining genomic integrity and enhancing survival in response to chemotherapy and ... , P.M. ( 2016 ) Distinct genetic control of homologous recombination repair of Cas9-induced double-strand breaks, nicks and paired nicks . Nucleic Acids Res ., 44 , 5204 - 5217 . 32. Falck , J. , Coates

Effects of <Emphasis Type=

leaves when significant amounts of proteins are leached (Benner et al. 1990) . The tannin-protein complexes are recalcitrant against microbial degradation and may therefore serve as a long-term source of ... . Differences between years appear to be most likely due to between-year salinity values. It could well be that all these significant differences are associated with more heavy rainfall in the period before the

Genetic analysis and QTL mapping of the seed hardness trait in a black common bean (<Emphasis Type=

Seed hardness trait has a profound impact on cooking time and canning quality in dry beans. This study aims to identify the unknown genetic factors and associated molecular markers to better ... identification of the QTLs and development of SNP markers associated with seed hardness can be applied for common bean variety improvement and genetic exploitation of these traits. Cooking quality; Seed hardness

Placental surface area mediates the association between <Emphasis Type=

receptor 2 (FGFR2) gene encodes a protein of the fibroblast growth factor receptor family. FGFR2 gene expression is associated with the regulation of implantation process of placenta which plays a vital role ... associated with increased susceptibility to chronic non-communicable diseases in adulthood, such as type 2 diabetes, obesity, hypertension, stroke, and cardiovascular diseases [ 4–10 ]. LBW is the result of

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) gene. The primer sets used are shown in Additional file 1: Table S1. The cox1 region was analyzed using an ABI Prism 3100-Avant Genetic analyzer (Applied Biosystems) and shown to have the A. ceylanicum ... genetic examinations using a PCR assay specific for the cox1 gene followed by sequencing (GenBank accession no. LC271184.1). The patient was treated with pyrantel pamoate and six worms (four females, two

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mediators of the extra interactions that appear to be needed to make sense of the 20 ÷ 30% deviation in RτDl(∗) , described, in the SM, by a tree level W -exchange. As well known a key feature that may hide ... of some of the vector states, with special emphasis on the single production of heavy gluons. Finally in Sect. 8 we summarise the overall picture. 2 The composite model defined The model is defined