Granular materials with irregular particle shapes undergo a myriad of temperature variations in natural and engineered systems. However, the impacts of cyclic temperature variations on the mechanics ... impacts of temperature variations on the mechanics of granular materials. To date, the majority of investigations have studied granular materials with spherical p articles1–9. These investigations have
The primary purpose of this study was to compare the ankle joint mechanics, during the stance phase of running, computed with a multi-segment foot model (MULTI; three segments) with a traditional
Measuring cellular and tissue mechanics inside intact living organisms is essential for interrogating the roles of force in physiological and disease processes. Current agents for studying the ... for real-time in vivo imaging of tissue mechanics. Nonetheless, it has poor sensitivity and spatiotemporal resolution. Here we describe magneto-gas vesicles (MGVs), protein nanostructures based on gas
detailed information on implant mechanics under load relative to intact conditions and fracture, providing insights into the failure mechanics of RSA implants. This protocol can be used to inform future ... of normal daily activity. Conclusion This experimental protocol shows the integration of large-volume micro-CT scanning alongside concurrent mechanical testing, to elucidate the micro-mechanics of the
Models exploring electrochemistry-mechanics coupling in liquid electrolyte lithium-ion battery anodes have traditionally incorporated stress impact on thermodynamics, bulk diffusive transport, and ... transformation in silicon),6–8 and constrained boundary effects (e.g., particle-particle, particle-conductive binder domain, particle-current collector contact, core-shell dynamics).9,10 Mechanics has a strong
: cryogenic microwave spectroscopy measuring density and coupling of TLS to mechanics, X-ray photoelectron spectroscopy and atomic force microscopy. We learn from these studies that, surprisingly, increases of
of Arp2/3 complex binding curved actin filaments. The small degree of twisting constrains models of actin filament mechanics. ... of Arp2/3 complex binding curved actin filaments. The small degree of twisting constrains models of actin filament mechanics. Arp2/3 complex is composed of seven protein subunits and nucleates the
followed by Molecular mechanics with generalized Born and surface area solvation (MM-GBSA). Further, the free energy landscape, the principal component analysis followed by the defined secondary structure of ... all four protein–ligand complexes have stable RMSD values, MM-GBSA binding energy was used for further evaluation. DB00644 DB01249 DB01698 The Molecular Mechanics energies combined with the
relationship for osteonal microcracking. The relationship/model is based on the formalism of Statistical Mechanics, allowing the degree of irreversibility to be calculated using the increase in entropy ... rib; Cortical bone; Statistical mechanics; Microcracking; Osteons; Entropy; Constitutive models Abbreviations 1 Introduction Digital image correlation Post-mortem human subject Strain energy density
quantify pulmonary mechanics via measures of quasi-static and dynamic compliances, transpulmonary pressure, and energetics when varying inflation frequency and volume. Each investigated mechanical parameter ... . Contradictory to limited previous clinical investigations of oxygenation and end-inspiratory measures, the mechanics-focused comprehensive findings presented here indicate lung properties are dependent on loading
.082495 PMID: 23470662 2. Farris DJ , Sawicki GS . The mechanics and energetics of human walking and running: a joint level perspective . Journal of The Royal Society Interface . 2012 ; 9 : 110 - 118 ... . Mechanics of walking and running up and downhill: A joint-level perspective to guide design of lower-limb exoskeletons . PloS one . 2020 ; 15 : e0231996. https://doi.org/10.1371/journal.pone. 0231996 PMID
mechanics via aspiration and cell spheroids incubated in pressure-controlled chambers, were each integrated into a CubeLab deployed to the ISS National Laboratory. For the first experiment, we report ... mineralization? Here, we aim to study the mechanotransduction mechanisms by which bone loss occurs in microgravity. Two automated experiments, microfluidic chips capable of measuring singlecell mechanics via
. Department of Mechanical Engineering, Clemson University , Clemson 1 . Shanghai Institute of Applied Mathematics and Mechanics, School of Mechanics 2 . Division of Applied Mathematics, Brown University ... potential to revolutionize various scienti¯c research ¯elds, including computational mechanics, materials science, and biomedical engineering. In the ¯eld of computational mechanics, various neural network
may improve mechanics, it also imparts brittleness. In soft tissue engineering, resilience against mechanical loads from mobile tissues is paramount. We report a hybrid aerogel that consists of self ... stretchable and tough hydrogels . Nature 489 , 133 - 136 ( 2012 ). 27. Edwards , S. F. Statistical mechanics with topological constraints: I. Proc . Phys. Soc . 91 , 513 - 519 ( 1967 ). 28. Gong , J. P
We derive simple bootstrap bounds on correlation functions of the BFSS matrix theory/D0-brane quantum mechanics. The result strengthens and extends Polchinski’s virial theorem bound to finite ... from the fermions 3 Discussion A Bound on Tr X2 using the supergravity solution B Bootstrapping off-diagonal elements of single particle quantum mechanics C Fermionic matrices D Rotational invariance
Ankle exoskeletons alter whole-body walking mechanics, energetics, and stability by altering center-of-mass (CoM) motion. Controlling the dynamics governing CoM motion is, therefore, critical for ... with cerebral palsy, ankle exoskeletons elicit diverse—and sometimes detrimental—impacts on gait mechanics, walking speed, step length, and the energetic cost of w alking1–4. Quantifying and
matrix architecture culminating in a mechanical response is not well defined. In this study, we investigated the effect of organized collagen matrix fibers on leader cell mechanics and demonstrate that ... , ITGα2, and vinculin may have a unique function in K14+ leader cells correlated with increased force exertion by leader cells. Discussion This study sought to better understand leader cell mechanics
Despite the astonishing successes of quantum mechanics, due to some fundamental problems such as the measurement problem and quantum arrival time problem, the predictions of the theory are in some ... understanding of the foundations of quantum mechanics. - I adjoint operator1, hence there is no agreed-upon way to n textbook quantum theory, time is a parameter, not a selfcompute the temporal probability
multiple in silico techniques including protein–ligand docking, molecular dynamics simulation, molecular mechanics-generalized Born surface area (MM-GBSA), and principal component analysis (PCA). Our results ... in total48. The protein α-carbon (Cα) root-mean-square deviation (RMSD) values were obtained with the Simulation Interactions Diagram Wizard in Desmond. The molecular mechanics-generalized Born surface
We give a geometric interpretation for the principle of stationary action in classical Lagrangian particle mechanics. In a nutshell, the difference of the action along a path and its variation ... a full physical account of the geometry of both Hamiltonian and Lagrangian mechanics which is founded on three assumptions: determinism and reversible evolution, independence of the degrees of freedom
