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Comparative genomics identifies distinct lineages of S. Enteritidis from Queensland, Australia

genomics to determine how these clades fit within the global S. Enteritidis population. Methods Sequencing of bacterial strains Salmonella enterica serovar Enteritidis strains included in this study were ... ):E236± 64 . Epub 2015/08/04. PMID: 26234259 . 7. Allard MW , Luo Y , Strain E , Pettengill J , Timme R , Wang C , et al. On the Evolutionary History, Population Genetics and Diversity among Isolates of

Genomics of Clostridium taeniosporum, an organism which forms endospores with ribbon-like appendages

molecules of each of the principal component proteins. This organism is interesting for many reasons. First, study of the appendage function might contribute to microbial ecology. Perhaps the appendages ... . 13. Krzywinski M , Schein J , Birol I , Connors J , Gascoyne R , Horsman D , et al. Circos, an information aesthetic for comparative genomics . Genome Res . 2009 ; 19 : 1639 ± 1645 . https://doi.org

Assessment of Genetics Understanding

to employ an experimental research design to quantify the degree to which situational features impact inferences about participants’ understanding of Mendelian genetics. Two participant samples from ... to some extent (Todd and Romine 2016, p. 1678). With improved understanding of genomics and molecular genetics, the limitations of traditional inheritance-centered approaches to genetics education

Post genomics era for orchid research

, Dendrobium officinale, and Apostaceae shengen. Here, we review the current progress and the direction of orchid research in the post genomics era. These include the orchid genome evolution, genome mapping ... (especially receptor‑ like kinase and terpene synthase), secondary metabolomics, and genome editing. Comparative genomics; Genome editing; Genome evolution; GWAS; Orchidaceae; Phalaenopsis; Post genomics era

Neuroimaging genomics in psychiatry—a translational approach

Neuroimaging genomics is a relatively new field focused on integrating genomic and imaging data in order to investigate the mechanisms underlying brain phenotypes and neuropsychiatric disorders ... predetermined protocols and criteria for study inclusion [ 37 ]. There is often a need to account for multiple testing in imaging genomics beyond that which is done in genetics alone. This is an important

Human genetics in troubled times and places

The development of human genetics world-wide during the twentieth century, especially across Europe, has occurred against a background of repeated catastrophes, including two world wars and the ... genetics and genomics, both in research and in its applications. There are many political and other groups eager to misrepresent and distort sensitive advances, and it will require both vigilance from people

Cyanobacterial diversity held in microbial biological resource centers as a biotechnological asset: the case study of the newly established LEGE culture collection

differential toxicities . BMC Genomics 15 : 83 Smith D , McCluskey K , Stackebrandt E ( 2014 ) Investment into the future of microbial resources: culture collection funding models and BRC business plans for ... Introduction Microbial biological resource centers (mBRCs) are qualitymanaged culture collections that ensure the ex situ preservation of microorganisms, while providing public access to their microbial

Correction to: Transethnic insight into the genetics of glycaemic traits: fine-mapping results from the Population Architecture using Genomics and Epidemiology (PAGE) consortium

, Minneapolis, MN , USA 3 Division of Public Health Sciences, Fred Hutchinson Cancer Research Center , 1100 Fairview Ave N., Seattle, WA 98109-1024 , USA 4 Stephanie A. Bien 5 Human Genetics Center, University of ... Medicine at Mount Sinai, New York, NY, USA 14 15 16 17 18 19 20 21 22 23 24 25 Department of Genetics, Rutgers University, Piscataway, NJ, USA Department of Statistics, Rutgers University, Newark, NJ, USA

Genetics and immunity in the era of single-cell genomics

Recent developments in the field of single-cell genomics (SCG) are changing our understanding of how functional phenotypes of cell populations emerge from the behaviour of individual cells. Some of ... methodological developments in the field of single-cell genomics (SCG) have unveiled new biological insights that were previously masked due to measurement approaches that used bulk samples of cells ( 1,2 ). By

Rhizospheric microbial communities associated with wild and cultivated frankincense producing Boswellia sacra tree

core fungal and bacterial microbial microbiome associated with this economically important tree. ... . Introduction Symbioses of microbial communities have been of special interest to ecologists to understand their role in plant growth and development under extreme living conditions such as desert conditions

Genomics for all in the 21st century?

As the field of genomics enters the second decade after the completion of the International Human Genome Project, human genomics research is still far from reflective of the ancestral diversity found ... them as a platform for greater community engagement in genomics. The Journal of Community Genetics in its aims and scope states that the journal is Ban international focal point for research in the ever

Transethnic insight into the genetics of glycaemic traits: fine-mapping results from the Population Architecture using Genomics and Epidemiology (PAGE) consortium

, Nashville, TN , USA 2 Division of Epidemiology and Community Health, University of Minnesota , Minneapolis, MN , USA 3 Human Genetics Center, University of Texas Health Science Center at Houston , Houston, TX ... Department of Genetics, Rutgers University , Piscataway, NJ , USA 7 Stephanie A. Bien 8 Epidemiology Program, University of Hawaii Cancer Center , Honolulu, HI , USA 9 Department of Medicine, Institute for

Genetics and genomics of dilated cardiomyopathy and systolic heart failure

American College of Medical Genetics and Genomics report that provides comprehensive guidelines on variant interpretation [24]. Genetic variants affecting systolic heart failure In this section, we review ... al. Standards and guidelines for the interpretation of sequence variants: a joint consensus recommendation of the American College of Medical Genetics and Genomics and the Association for Molecular

Comparative genomics of two super-shedder isolates of Escherichia coli O157:H7

a rate (≥ 104 CFU/g of feces) that is several orders of magnitude greater than other colonized cattle and play a major role in the prevalence and transmission of O157. To better understand microbial ... with super-shedding [3, 6±9]. However, very little is known about the microbial factors that may contribute to super-shedding including the presence of virulence and adherence genes, the ability to form

Comparative genomics and phylogenomic analyses of lysine riboswitch distributions in bacteria

discovered so far, three are known to regulate the concentration of biologically encoded amino acids glycine, lysine, and glutamine. While some comparative genomics studies of riboswitches focusing on their ... essential metabolic pathways. Natural as well as synthetic compounds that are designed to mimic riboswitch-binding metabolites and possessing anti-microbial properties have been reported for thiamine

Computing patient data in the cloud: practical and legal considerations for genetics and genomics research in Europe and internationally

collaborative processing of these data within a flexibly scalable infrastructure. Clouds offer novel research opportunities in genomics, as they facilitate cohort studies to be carried out at unprecedented scale ... adequate solution for genetics and genomics research in Europe, and under certain conditions between Europe and international partners. This approach could represent a sensible middle ground between

Population genetics, community of parasites, and resistance to rodenticides in an urban brown rat (Rattus norvegicus) population

scarce. The main purpose of this study was to characterize an urban brown rat population from Chanteraines park (Hauts-de-Seine, France), with regards to haematology, population genetics, immunogenic ... tracking the population ecology of urban rats can provide important insights into factors influencing pathogen persistence, spread, and evolution [ 17 ]. Landscape genetics is now recognized as an

Characterization of the emerging zoonotic pathogen Arcobacter thereius by whole genome sequencing and comparative genomics

present, only the genome of the species Arcobacter butzleri has been analysed, and still little is known about their physiology and genetics. The species Arcobacter thereius has first been isolated from ... 2x300 bp paired-end reads for each sequenced fragment. Base calling and primary quality assessments were performed using Illumina's Basespace genomics cloud computing environment. Using CLC bio Genomics

Exploring public genomics data for population pharmacogenomics

variants involved in drug response and metabolism in Sri Lankan populations . Pharmacogenet Genomics . 2016 ; 26 : 28 ± 39 . https://doi.org/10.1097/FPC.0000000000000182 PMID: 26444257 8. Nebert D , Menon A ... , Weinshilboum R , Cox NJ , et al. Genomewide association studies in pharmacogenomics: successes and lessons . Pharmacogenet Genomics . 2010 ; 1 . PMID: 20639796 15. Altman RB , Whirl-Carrillo M , Klein TE

Genomics of Lithium Action and Response

effects. Transcriptomic, genomic, and cell-model research strategies have all been deployed in the search for the genetic factors and biological systems that mediate the interaction between genetics and the ... to established psychiatric biology, suggesting that larger surveys are required. Finally, a fourth study carried out by the Consortium on Lithium Genetics (ConLiGen) consisted of a genome-wide