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Lymph node pathology using optical spectroscopy in cancer diagnostics

, Gloucestershire Hospitals NHS Foundation Trust, Gloucester, UK 2Gastrointestinal Surgical Unit, Gloucestershire Hospitals NHS Foundation Trust, Gloucester, UK 3Department of Pathology, Gloucestershire Hospitals NHS

Proteasome-targeted nanobodies alleviate pathology and functional decline in an α-synuclein-based Parkinson’s disease model

Therapeutics designed to target α-synuclein (α-syn) aggregation may be critical in halting the progression of pathology in Parkinson’s disease (PD) patients. Nanobodies are single-domain antibody ... -to-cell transmission of toxic α-syn species lends weight to the theory of prion-like spatiotemporal progression of pathology.10,11,12 Thus, methods to interrupt proteinaceous inclusion formation and

Book review—Diagnostic Pathology: Cytopathology, 2nd edition

Sacred Heart , Largo Francesco Vito, 1, 00168 Rome , Italy 1 Esther Diana Rossi Diagnostic Pathology: Cytopathology, 2nd edition Dina R. Mody & Michael J. Thrall & Savitri Krishnamurthy Print ISBN

Intra-individual alterations of serum markers routinely used in forensic pathology depending on increasing post-mortem interval

in post-mortem investigations of both disciplines, forensic and clinical pathology, is still not well-established and is not used routinely, although biochemistry is declared necessary to solve the ... on forensic application. Am. J. Forensic Med. Pathol. 14, 91–117 (1993). Article Google Scholar4. Luna, A. Is post-mortem biochemistry really useful? Why is it not widely used in forensic pathology

Transcriptional network analysis of human astrocytic endfoot genes reveals region-specific associations with dementia status and tau pathology

in the aging rodent brain is associated with reduced perivascular AQP4 localization, and in human subjects, reduced perivascular AQP4 localization is associated with AD diagnosis and pathology. Using ... pathology. Using human transcriptomic data, we demonstrate that expression of perivascular astroglial gene products dystroglycan (DAG1), dystrobrevin (DTNA) and alpha-syntrophin (SNTA1), are associated with

Integrated pathology and radiology learning for a musculoskeletal system module: an example of interdisciplinary integrated form

Integrated pathology and radiology learning for a musculoskeletal system module: an example of interdisciplinary integrated form Ihab Shafek Atta,1 Fahd Nasser AlQahtani2 1Pathology Department ... asser AlQahtani 0 0 radiology Department, Faculty of Medicine, Albaha University , Al-Aqiq, saudi Arabia 1 Pathology Department, Faculty of Medicine, Al-Azhar University , cairo (Assuit Branch) , Egypt 8

A Novel, Patient-Specific Mathematical Pathology Approach for Assessment of Surgical Volume: Application to Ductal Carcinoma in situ of The Breast

We introduce a novel “mathematical pathology” approach, founded on a biophysical model, to identify robust patient-specific predictors of tumor growth useful in clinical practice to improve the ... Analytical Cellular Pathology A novel, patient-specific mathematical pathology approach for assessment of surgical volume: Application to ductal carcinoma in situ of the breast Department of

Dichotomous associations of liver pathology with hepatocellular carcinoma morphology in Middle Africa: the situation in Cameroon

retrospective study was conducted in the Pathology Unit of Centre Pasteur of Cameroon recognized as the national reference Laboratory of the Country. This study was the continuity of another project on primary ... , characters of the underlying pathology affecting non-tumor livers were apparently influencing tumor morphology. Of course, necro-inflammatory activity and fibrosis were positively correlated. Indeed, tissues

Placenta Accreta Spectrum: A Review of Pathology, Molecular Biology, and Biomarkers

trimester. This review aims to assess the existing evidence on the pathology, molecular biology, and biomarkers associated with PAS. 2. Pathology PAS refers to a spectrum of abnormal placental adherence ... of this article, and a number of studies describing the pathology of PAS in detail have been published [12–15]. Abnormal adherence of the placenta to the myometrium is established in very early

Book Review—Pulmonary Pathology, 2nd Edition

, Portugal 1 Lina Carvalho Dani S. Zander and Carol F. Farver Pulmonary Pathology, 2nd Edition (A Volume in the Series: Foundations in Diagnostic Pathology) Print ISBN 9780323393089 776 pp £128.99 https ... ://www.uk.elsevierhealth.com/pulmonary-pathology9780323393089.html - The field of airways and lung pathology has evolved greatly in the last years, and current accomplishments in target therapy and personalized medicine have

Innovating undergraduate pathology education through public engagement

The trends in modern undergraduate medical education focus on a patient-centred approach through problem-based learning over the traditional modular curriculum. Integrating pathology into this style ... dilution of core scientific principles which may have contributed to reduced understanding and interest in the subject. We aim to innovate pathology education by utilising National Pathology Week which is

Cryptic species of Curvularia in the culture collection of the Queensland Plant Pathology Herbarium

Several unidentified specimens of Curvularia deposited in the Queensland Plant Pathology Herbarium were re-examined. Phylogenetic analyses based on sequence data of the internal transcribed spacer ... of Curvularia maintained in the culture collection held in the Queensland Plant Pathology Herbarium (BRIP) were compared with ex-type and reference isolates. Thirteen new species of Curvularia were

Riluzole reduces amyloid beta pathology, improves memory, and restores gene expression changes in a transgenic mouse model of early-onset Alzheimer’s disease

cognition in aged rats. However, riluzole’s effect on amyloid beta (Aβ) pathology, a major histopathological hallmark of AD, remains unclear. 5XFAD transgenic mice, which harbor amyloid β precursor protein ... compromised first in the progression of AD, causing significant memory loss in affected individuals12,13. However, the effect of riluzole on amyloid pathology, a hallmark of AD and considered to be one of the

Alzheimer’s disease pathology propagation by exosomes containing toxic amyloid-beta oligomers

The gradual deterioration of cognitive functions in Alzheimer’s disease is paralleled by a hierarchical progression of amyloid-beta and tau brain pathology. Recent findings indicate that toxic ... of Public Health and Caring Sciences , Geriatrics , Uppsala University , Uppsala , Sweden 2 Department of Pathology, Department of Clinical and Experimental Medicine, Linköping University , Linköping

Speech-language pathology Student Participation in Verbal Reflective Practice Groups: perceptions of development, value and group condition differences.

group conditions. Twenty-seven undergraduate speech-language pathology students participated in the study. A two-condition, non-randomised, pre-test post-test design was employed with two groups (a ... Footnote Acknowledgements The authors would like to thank all speech-language pathology students who participated in this study during the 2015 academic year. Authors Gina D. Tillard, Kate Cook, Daniel

Pathology and images of radiation-induced hepatitis: a review article

radiological changes of hepatic tumors and the surrounding parenchyma of the irradiated liver. Radiation-induced liver disease; Focal liver injury; Focal liver reaction; Hepatocellular carcinoma; Pathology ... significant clinical associations of radiological findings with pathology. Here, we use RILD to describe the effects of whole (classical) or focal (nonclassical) liver irradiation according to the original

Quality in pathology

. It is, at least partly, an experience, a feeling and key to being human. Virchows Archiv has decided to launch a special section entitled BQuality in Pathology,^ an idea that I welcome very much. But ... some issues regarding grading and classification, the vast majority of patients are correctly treated, thanks to very effective and cheap pathology. Furthermore, clinicians and patients generally have a

The role of the pathology department in the preanalytical phase of molecular analyses

The role of the pathology department in the preanalytical phase of molecular analyses Sergiu Susman,1,2 Ioana Berindan-Neagoe,3 Bobe Petrushev,3 Radu Pirlog,2 Ioan-Stefan Florian,4 Carmen-Mihaela ... Morphological Sciences 2 Department of Pathology, Imogen Research Center 3 Department of Haematopathology, Tygerberg Academic Hospital , Tygerberg , South Africa 4 Department of Hematology, Iuliu Hatieganu