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Data Science: the impact of statistics

most important discipline to analyze and quantify uncertainty. We give an overview over different proposed structures of Data Science and address the impact of statistics on such steps as data ... . : Uncovering distinct protein-network topologies in heterogeneous cell populations . BMC Syst. Biol . 9 ( 1 ), 24 ( 2015 ) 50. Wu , J.: Statistics = data science? ~jeffwu

Clinical protein science developments for patient monitoring in hospital central laboratories

Biological and Medical Mass Spectrometry, Lund University , BMC D13, 22100 Lund , Sweden 1 Clinical Protein Science & Imaging, Biomedi‐ cal Center, Department of Biomedical Engineering, Lund University , BMC ... common routine tests in clinical chemistry laboratories are; CBC (complete blood count), electrolytes, hormones, coagulation parameters, disease specific protein biomarkers and plasma biomarker proteins

Citizen Science Book Resources

Linda Silka briefly reviews The Rightful Place of Science: Citizen Science, edited by Darlene Cavalier and Eric B. Kennedy; Citizen Science for All: A Guide for Citizen Science Practitioners; Citizen ... useful he interest in citizen science is taking off, and the ideas for citizen science initiatives. In this piece, I offer a few suggestions about books likely to be of particular interest to policymakers

Determining the minimum number of protein-protein interactions required to support known protein complexes

The prediction of protein complexes from protein-protein interactions (PPIs) is a well-studied problem in bioinformatics. However, the currently available PPI data is not enough to describe all known ... H, Leutwein C, Mellwig C, Fischer S, et al. Structure-based assembly of protein complexes in yeast. Science. 2004; 303(5666):2026±2029. 1092645 PMID: 15044803 Mering C

The future is now: cutting edge science and understanding toxicology

, Gwangju Institute of Science and Technology , 1 Oryong-Dong, Buk-Gu, Gwangju 61005 , Republic of Korea Introduction In 2016, the scope of Cell Biology and Toxicology was expanded to provide greater ... emphasis on clinical and translational research, for example, by focusing on gene-/protein-based regulation, single-cell genomics, and systems biology in drug discovery (Gu and Wang 2016) . In this

Megakaryocyte lineage development is controlled by modulation of protein acetylation

Treatment with lysine deacetylase inhibitors (KDACi) for haematological malignancies, is accompanied by haematological side effects including thrombocytopenia, suggesting that modulation of protein ... haematological malignancies [17±19]. KDACi inhibit deacetylation of histone and non-histone protein substrates, suggesting that the regulation of protein acetylation plays an important role in the cellular effects

Prognostic value of C-reactive protein levels in patients with bone neoplasms: A meta-analysis

Objective The aim of this study was to conduct a meta-analysis of retrospective studies that investigated the association of preoperative C-reactive protein (CRP) levels with the overall survival (OS ... -reactive protein levels in patients with bone neoplasms. (DOC) Acknowledgments This study was funded by the National Natural Science Foundation of China (No.81372180). Author Contributions

Sex/Gender/Sexual Science Research 24/7

, communal process that keeps the sexual science engine running. New Editorial Board Members (2018) Table 1 shows Editorial decision data for initial submissions for 2015 and 2016 as a function of who ... accompanied by penetrating commentaries, which are also reviewed by Vasey, with a response by the author(s). More are in the sexual science pipeline. I expect these Target Articles will make a contribution to

Germanium as a scalable sacrificial layer for nanoscale protein patterning

functionalization. Since Ge dissolves in 0.35% hydrogen peroxide (H2O2) in water but not in organic solvents, Ge can be removed after patterning without significantly affecting protein activities. In this paper, we ... :// 1 UC Berkeley-UCSF Graduate Program in Bioengineering, University of California, Berkeley, CA, United States of America, 2 Electrical Engineering and Computer Science Department, University of

Science Academies’ Refresher Course in Statistical Mechanics

(Kolkata), Somendra M Bhattacharjee (Bhubaneswar), Varsha Banerjee, Delhi 1 Sponsored by Indian Academy of Sciences, Bengaluru Indian National Science Academy, New Delhi The National Academy of Sciences

Science Academies’ Refresher Course on Experimental Physics

University , Itanagar, Arunachal Pradesh from 26 1 Sponsored by Indian Academy of Sciences, Bengaluru Indian National Science Academy, New Delhi The National Academy of Sciences, India , Allahabad 2 at Rajiv ... including universities, autonomous colleges, and advanced science institutions involved in education. Over 1800 participants have been trained so far and more than 250 kits have been sold. The course will be

Data Science: a proposal for a curriculum

We define Data Science as the combination of statistical and computational data analytic approaches. We argue that only this combination allows to tackle the many problems occurring in today’s Big ... possible curriculum, which focuses on both statistics and computer science aspects of data analytics. The proposed curriculum is implemented in the Data Science master program run at the University Munich

Fast evaluation of protein dynamics from deficient 15N relaxation data

Simple and convenient method of protein dynamics evaluation from the insufficient experimental 15N relaxation data is presented basing on the ratios, products, and differences of longitudinal and ... , Polish Academy of Science , Pawinskiego 5A, 02-106 Warszawa , Poland 2 Division of Biological and Environmental Sciences and Engineering, King Abdullah University of Science and Technology (KAUST) , Thuwal

Indicator system for managing science, technology and innovation in universities

The formulation of standardized measurement indicators of science, technology and innovation at the international, regional and institutional level remains a continuing need. Although there are

Gastrokine 1 protein is a potential theragnostic target for gastric cancer

proteins using the protein microarray assay and investigated whether GKN1 is one of the exosomal cargo proteins by western blot, immunoprecipitation, and immunofluorescent assays. Cell proliferation and ... serum GKN1 as a diagnostic marker for gastric cancer was determined by ELISA assay. Results In protein microarray assay, GKN1 binding to 27 exosomal proteins was clearly observed. GKN1 was expressed in

Robust signal peptides for protein secretion in Yarrowia lipolytica: identification and characterization of novel secretory tags

Upon expression of a given protein in an expression host, its secretion into the culture medium or cell-surface display is frequently advantageous in both research and industrial contexts. Hence ... secretion of the proteins gain considerable interest. Yarrowia lipolytica has emerged as an efficient protein expression platform, repeatedly proved to be a competitive secretor of proteins. Although the key

Three controversies in health data science

three controversies discussed in this paper relate to core challenges for research with health data and define an essential research agenda for the health data science community. ... 2 Division of Informatics , Imaging, and Data Science , School of Health Sciences, University of Manchester , Manchester , UK The routine operation of modern healthcare systems produces a wealth of

High-quality genomic study of a rubber plant | National Science Review | Oxford Academic

biosynthetic pathway studies. The manuscript reports a high-quality draft genome of TKS with a total length of 1.29 Gb, containing 46 731 predicted protein-coding genes. In-depth analysis of the genome explores

Expression of recombinant HBD3 protein that reduces

reagent. However, its minimal inhibitory concentration to M. bovis is not yet reported. In this study, we first purified HBD3 protein by recombinant-DNA technology and prokaryotic expression system ... , Northwest A&F University , Yangling, Shaanxi , China 1 College of Animal Science and Veterinary Medicine, Shandong Agricultural University , Taian, Shandong , China Bovine tuberculosis is a disease caused by