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The new Systematic Coronary Risk Evaluation (SCORE2 and SCORE2-OP) estimates the risk of arterial occlusive events in chronic myeloid leukemia patients treated with nilotinib or ponatinib

stratified according to the Systematic Coronary Risk Evaluation (SCORE2) and SCORE2-Older Persons (SCORE2-OP). This updated algorithm from the European Society of Cardiology (ESC) estimates a 10-year risk of ... SCORE2/ SCORE2-OP algorithm translated more patients (50.2%) to the high-very high cardiovascular risk category than the previous SCORE (25.3%). Patients with a high to very high SCORE2/SCORE2-OP risk

On the comparison between pre- and post-surgery nasal anatomies via computational fluid dynamics

surgery planning, by comparing a pre-operative (pre-op) situation with the outcome of virtual surgery (post-op). An equivalent comparison is involved when considering distinct anatomies in the search for ... assumption that results are unchanged, which reflects our limited understanding of the driver of the respiratory function. The study describes how to set up a meaningful comparison. A pre-op anatomy, derived

Detection the severity of organophosphate intoxication using sensitive serum biomarkers S100B and amyloid β (Aβ) in Egyptian subjects

Organophosphate (OP) is a compound considered the main leading cause of morbidity and mortality from poisoning worldwide. Serum pseudocholinesterase was evaluated as a diagnostic indicator; it cannot ... -off values of serum S100B and amyloid β for neurological affection severity. This study was carried out on sixty OP-impaired patients; in addition, 20 normal controls were included. Serum liver and

Do peri-operative parathyroid hormone (PTH) analogues improve bone density and decrease mechanical complications in spinal deformity correction?—a minimum 2-year radiological study measuring Hounsfield units

surgery on pre-op and post-op CT scans. The mean age of patients in this study was 70 (52–84, SD 7). Mean follow-up was 66 (24–132, SD 33) months. Twenty-three patients met criteria for severe deformity ... included in this study. Hounsfield units were measured off of the L1-L3 levels for all patients before and after surgery on pre-op and post-op CT scans. Result The mean age of patients in this study was 70

Medium-chain fatty acids as an alternative treatment for denture stomatitis in older people

To determine the effect of medium-chain fatty acids (MCFA) on the severity of denture stomatitis (DS) and the counts of Candida spp. in older people (OP) wearing removable prostheses (RP). This ... -chain fatty acids (MCFA) on the severity of denture stomatitis (DS) and the counts of Candida spp. in older people (OP) wearing removable prostheses (RP). Materials and methods This randomized, controlled

Correlation of R2* with fat fraction and bone mineral density and its role in quantitative assessment of osteoporosis

To investigate the correlation of R2* with vertebral fat fraction (FF) and bone mineral density (BMD), and to explore its role in the quantitative assessment of osteoporosis (OP). A total of 83 ... explore its role in the quantitative assessment of osteoporosis (OP). Methods A total of 83 patients with low back pain (59.77 ± 7.46 years, 30 males) were enrolled, which underwent lumbar MRI in IDEAL-IQ

Simulating deployment of genetic gain in a radiata pine breeding program with genomic selection

investigate these concepts, comparing three deployment scenarios: half-sib open-pollinated orchards (OP), full-sib control-pollinated orchards (CP) and clonal deployment through somatic embryogenesis. When ... accounting for time, genomic selection in OP, CP and clonal deployment pathways increased genetic gain by 9.5%, 15.9% and 44.6% respectively compared to phenotypic selection. The optimal orchard scenario would

Long-term follow-up suggests high satisfaction rates for bulbomembranous radiation-induced urethral stenoses treated with anastomotic urethroplasty

queries at 4 months. PROMs were assessed annually thereafter, and cystoscopy was performed for adverse change in PROMs or worsening uroflow/PVR parameters. PROMs were compared at pre-op, post-op, and most ... , post-op, and most recent follow-up. Results 23 patients met inclusion criteria. Short-term anatomic success was 95.7%. At a mean follow-up of 73.1 months (9.1-228.9), one late recurrence occurred for an

Is the oxidative potential of components of fine particulate matter surface-mediated?

ALI mixing. The resulting oxidative potential (OP) of selected quinones and other PAH derivatives were found to exceed the OP resulting from bulk mixing of the same amounts of redox-active substances ... depends not only on the PM substance properties but also on the ELF interface properties and uptake mechanisms. OP measurements based on bulk mixing of phases may not represent the effective OP in the human

Does lucency equate to revision? A five-year retrospective review of Attune and Triathlon total knee arthroplasty

lines were assessed for those with a minimum two-year radiological follow-up (Attune® = 338; Triathlon® = 231). X-rays were taken post op, at 6 months, 2 years and 5 years. Radiolucent lines were ... the Log Rank method to determine statistical significance. The Oxford Knee Score and EQ-5D-5L, were collected pre-op, at 6 months, 2 years and 5 years post-operatively and compared using the Kruskal

Sarcopenia and body fat change as risk factors for radiologic incisional hernia following robotic nephrectomy

detect an association between sarcopenia and risk of IH development. In terms of subcutaneous fat change from pre-op, both lower and higher values were associated with IH development (HR (95% CI) 2.1 (1.2 ... < Q1 and ≥ Q3, respectively). Similar trend was found for visceral fat area changes from pre-op with a HR of 2.8 for < Q1 and 1.8 for ≥ Q3. Conclusion Both excessive body fat gain and loss are associated

Accuracy and applicability of dual-energy computed tomography in quantifying vertebral bone marrow adipose tissue compared with magnetic resonance imaging

To evaluate the accuracy of dual-energy computed tomography (DECT) in quantifying bone marrow adipose tissue (BMAT) and its applicability in the study of osteoporosis (OP). A total of 83 patients ... marrow adipose tissue (BMAT ) and its applicability in the study of osteoporosis (OP). Methods: A total of 83 patients with low back pain (59.77 ± 7.46 years, 30 males) were enrolled. All patients

Impact of pulmonary valve replacement on left and right ventricular function using strain analysis, in children with repaired tetralogy of Fallot

value) and early (mean = 10.4 days) and late (mean = 7.4 months) postop LVEF. Paired T-Test showed significant difference between GLS of LV and RV before and late after operation (op), however, without ... patients pre and post-PVR, Paired T-Test showed significant difference between GLS of LV and RV before and late post-op, however, without significant changes early after operation (Table  3), as illustrated

Employment trajectories until midlife in schizophrenia and other psychoses: the Northern Finland Birth Cohort 1966

Psychoses are associated with poor labour market attachment, but few studies have compared schizophrenia (SZ) and other psychoses (OP). Moreover, studies on long-term employment trajectories over ... courses are lacking. We compared 30 year employment trajectory patterns in a general population sample among individuals with SZ, OP, and those with no psychosis (NP). Methods Utilising the Northern Finland

Valorization of orange peels in a biorefinery loop: recovery of limonene and production of volatile fatty acids and activated carbon

-extraction OPs were firstly converted into biochar through slow pyrolysis at 550 °C for 1 h and then physically activated with CO2 at 880 °C for 1 h. Extraction did not appreciably affect OP properties, while ... . Physical activation of OP biochar increased its surface area by almost ten times, from 40 to 326 m2/g, proving the effectiveness of the treatment. Orange peel; Biorefinery; Limonene; Volatile fatty acids

Retrospective clinical and X-ray-based outcome analysis of a short-stem hip arthroplasty taking into account the operative learning curve over 7 years in the 3-year control course

ratio (FFR), and migration) and ancillary outcome parameters (Harris Hip Score (HHS), blood loss, operating time, and complications). This period was divided into five times: 1st-day post-op, 6 M, 12 M ... -op), after 6 months (6 M), 12 months (12 M), 24  months (24  M), and 36  months (36  M). The patient population was divided into seven groups (1–7) regarding the patients' respective dates of surgery

PENS approach for breaking bad news in the oncology outpatient setting: a real-world report

in oncology outpatient (OP) settings. This observational study was conducted in a university teaching hospital, including cancer patients who were unaware of their condition and willing to discuss ... method for BBN, especially when the oncologists have higher OP workloads. More extensive trials are required to validate the protocol in other settings. Trial registration Clinical Trial Registry of India

Mapping the obesity problems scale to the SF-6D: results based on the Scandinavian Obesity Surgery Registry (SOReg)

Obesity Problem Scale (OP) is a widely applied instrument for obesity, however currently calculation of health utility based on OP is not feasible as it is not a preference-based measure. Using data ... algorithm is robust to the effect of surgery. Method The source data SOReg (n = 36 706) contains both OP and SF-36, collected at pre-surgery and at 1, 2 and 5 years post-surgery. The Ordinary Least Square

Automated consistent truncations and stability of flux compactifications

automated, for any possible configuration of Op-planes and Dp-branes. We then prove that any such truncation is consistent. We further compute the mass spectrum and analyse the stability of many de Sitter ... orientifold – 1 – Op-planes. The latter are smeared, going together with a constant dilaton and no warp factor. This common ansatz is discussed in more detail in section 2. While this seems at first sight

Venous thromboembolism following colectomy for diverticular disease: an English population-based cohort study

0.20–0.65) compared to open colectomies at 30 days post-op. At 90 days following emergency resections, VTE risks remained raised compared to elective colectomies. Following emergency colectomy for ... ) compared to open colectomies at 30 days post-op. At 90 days following emergency resections, VTE risks remained raised compared to elective colectomies. Conclusion Following emergency colectomy for