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Automatically listing senior members of departments as co-authors is highly prevalent in health sciences: meta-analysis of survey research

, 28% [95% CI 22–34] of researchers (10 surveys, 2180 respondents) felt that this practice was ‘never’, 24% [95% CI 22–27] ‘rarely’, 25% [95% CI 23–28] ‘sometimes’, 13% [95% CI 9–17] ‘most of the time ... of the justification ‘always justified’ Review item 3a 28% [95% CI 22–34] (2180 respondents in 10 surveys) Review item 3a 24% [95% CI 22–27] (2180 respondents in 10 surveys) Review item 3a 25% [95

Expression of semaphorin 3A (SEMA3A) in breast cancer subtypes

Breast cancer is a major health concern, and its accurate diagnosis and management depend on identifying its histological type and biological subtype. Semaphorin-3A (SEMA3A) is a membrane protein ... cores cut before. Then, slides were baked for at 60 min in 60 °C. A Semaphorin 3A, clone EPR19367 was used to demonstrate expression of the secreted protein. Deparaffinization, rehydration and heat

What Egyptian Papyri Did Joseph Smith Possess?

Papyri, 205–7. 22. Rhodes, Books of the Dead Belonging to Tshemmin and Neferirnub, 57. 23. Malcom Mosher Jr., “New Light on P. Joseph Smith 2 and 3,” in The Book of the Dead, Saite through Ptolemaic

Synthesis and molecular docking simulations of novel azepines based on quinazolinone moiety as prospective antimicrobial and antitumor hedgehog signaling inhibitors

diazepines (3a–d) or with 2-aminophenol to offer oxazepine (4a–d). The structure of the synthesized compounds was confirmed via melting points, elemental analyses, and different spectroscopic techniques ... anticancer potential. Our results showed that, diazepine (3a) and oxazepine (4a) offered the highest binding energy against the target OMPA/ exo‑1,3‑beta‑glucanase proteins and exhibited the potent

The Ancient Owners of the Joseph Smith Papyri

Religious and Cultural Background of Joseph Smith Papyrus I,” Journal of the Book of Mormon and Other Restoration Scripture 22, no. 1 (2013): 20–33. 12. John Gee, “Some Puzzles from the Joseph Smith Papyri

Smith-specific regulatory T cells halt the progression of lupus nephritis

nephritis is associated with autoreactivity to the Smith (Sm) autoantigen and the human leucocyte antigen (HLA)-DR15 haplotype; hence, we investigated the potential of Sm-specific Tregs (Sm-Tregs) to suppress ... manifestation of SLE, is an important contributor to disease related morbidity and mortality7. The presence of LN is strongly associated with autoreactivity to the Smith (Sm) autoantigen8, which is in turn

Design, synthesis and in vitro anticancer activity of some new lomefloxacin derivatives

position 3 and 7 were synthesized and screened for cytotoxic activity utilizing 60 different human cancer cell lines. Furthermore, compounds 3a,b,c,e that revealed potent broad-spectrum anticancer activity ... arrest at the G2-M phase. Moreover, the mechanism of action was determined by determining the topoisomerase inhibitory activity and the molecular modeling study. Compounds 3a,b,c,e showed broad spectrum

The Relationship between the Book of Abraham and the Joseph Smith Papyri

-historicity -of-the-book-of-abraham. 13. See Karl C. Sandberg, “Knowing Brother Joseph Again: The Book of Abraham, and Joseph Smith as Translator,” Dialogue 22, no. 4 (Winter 1989): 17–38; Samuel Morris Brown

Knockdown of circ-Gatad1 alleviates LPS induced HK2 cell injury via targeting miR-22-3p/TRPM7 axis in septic acute kidney

apoptosis, proliferation ability, ROS and inflammatory cytokines level. Bioinformatics and luciferase report analysis confirmed that both miR-22-3p and TRPM7 were downstream targets of circ-Gatad1 ... luciferase reporter analysis confirmed that miR-22-3p inhibited luciferase activity in wild-type cells, but not in mutated cell lines (Fig. 3A and B), suggesting that miR-22-3p was the target of circ-Gatad1

Synthesis of novel azo pyrazole disperse dyes for dyeing and antibacterial finishing of PET fabric under supercritical carbon dioxide

) produced 1-((aryldiazenyl) cyanoacetyl piperidines (3a–d). To create the derivatives of 4-(phenyldiazenyl)-5-(piperidin-1-yl)-1H-pyrazol-3-amine (5a), the propane nitriles (3a–d) were condensed with ... , which was conducted using the AATCC method, revealed that some of the compounds (3a-d) and (4a-d) had impressive antibacterial capabilities against the researched +ve and gram −ve bacteria. For eight

Favourable neurological outcome following paediatric out-of-hospital cardiac arrest: authors’ reply

contributions AF: Conceptualisation, Writing– original draft. RA, RG: Writing– review & editing. MM: Writing– review & editing, Formal Analysis. UP: Supervision, Writing– original draft. All authors have read and ... approved the final version of the manuscript. Funding Not applicable. Data availability Not applicable. Declarations Education, Implementation and Team Task Force Chair. All other authors declare that

Exosome microRNA-22 inhibiting proliferation, migration and invasion through regulating Twist1/CADM1 axis in osteosarcoma

This study aims to the function of miR-22 original mesenchymal stem cells (MSC) on osteosarcoma (OS) proliferation, migration and invasion. Bio-informatics analysis including GEO2R analysis, Gene ... , integration analysis were used to confirmed the target genes (miR‑22, Twist1, CADM1) in OS. RT‑qPCR and western blotting confirmed the different expression of miR‑22, Twist1, CADM1 in OS tissues, MG63 and Saos

Good Fences Make Good Governments

In this issue's Margaret Chase Smith Essay, Ambassador John K. Veroneau describes a new paradigm that he believes is needed to rejuvenate our society, rebuild trust in our government, and renew pride

Book Review of Grandparents Raising Grandchildren: Coping with Addiction By Andrea Smith, PhD and Linda Dannison, PhD

Book Review of Grandparents Raising Grandchildren: Coping with Addiction By Andrea Smith, PhD and Linda Dannison, PhD ... Smith, PhD, and Linda Dannison, PhD. It is relevant and timely and is specifically designed for kin caregivers in this difficult situation. The book addresses the challenges families face, provides

New trends in cell death: overview of the International Society of Cell Death (ICDS) annual meeting in Johannesburg South Africa (May 19-22, 2023)

Cronjé et al. Cell Communication and Signaling (2024) 22:180 https://doi.org/10.1186/s12964-024-01534-9 Cell Communication and Signaling Open Access EDITORIAL New trends in cell death: overview ... on May 19–22 (https://celldeath-apoptosis.org) with “New Trends in Cell Death” as the main meeting theme. This was the 29th anniversary of the ICDS Society, a group that was started in 1994 at

Novel synthesis of new triazine sulfonamides with antitumor, anti-microbial and anti-SARS-CoV-2 activities

50 (IC50) of a representative compound from the novel triazine sulfonamide category. Compound 3a demonstrated potent antiviral activity against SARS-CoV-2 with IC50 = 2.378 µM as compared to the ... the triazine ring [22]. The triazine ring system constitutes one of the most promising scaffolds for drug discovery [23–27]. Triazine derivatives are biologically potent compounds with inhibitory

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overall, reducing their overall risk of cardiovascular mortality, thus confounding the observed association. The authors also deviated from their protocol and created three categories of oral hygiene ('poor ... epidemiology.4 To support OHS stability through life, authors cited a study5 comparing toothbrushing duration and number of strokes in videos of participants brushing their teeth in the 1970s with videos of a