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Search: authors%3A%22Neville Q. Verlander%22

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Automatically listing senior members of departments as co-authors is highly prevalent in health sciences: meta-analysis of survey research

, 28% [95% CI 22–34] of researchers (10 surveys, 2180 respondents) felt that this practice was ‘never’, 24% [95% CI 22–27] ‘rarely’, 25% [95% CI 23–28] ‘sometimes’, 13% [95% CI 9–17] ‘most of the time ... of the justification ‘always justified’ Review item 3a 28% [95% CI 22–34] (2180 respondents in 10 surveys) Review item 3a 24% [95% CI 22–27] (2180 respondents in 10 surveys) Review item 3a 25% [95

Expression of semaphorin 3A (SEMA3A) in breast cancer subtypes

Breast cancer is a major health concern, and its accurate diagnosis and management depend on identifying its histological type and biological subtype. Semaphorin-3A (SEMA3A) is a membrane protein ... ( 2021 ). 11. Hu , Z. Q. et al. Overexpression of semaphorin 3A promotes tumor progression and predicts poor prognosis in hepatocellular carcinoma after curative resection . Oncotarget 7 , 51733 - 51746

Leader–follower UAVs formation control based on a deep Q-network collaborative framework

This study examines a collaborative framework that utilizes an intelligent deep Q-network to regulate the formation of leader–follower Unmanned Aerial Vehicles (UAVs). The aim is to tackle the ... cooperating UAVs. Their approach utilized a Deep Q-Network (DQN) framework. The study conducted a simulation of the air warfare job using a dual-UAV olive formation. The findings indicated that the suggested

Synthesis and molecular docking simulations of novel azepines based on quinazolinone moiety as prospective antimicrobial and antitumor hedgehog signaling inhibitors

diazepines (3a–d) or with 2-aminophenol to offer oxazepine (4a–d). The structure of the synthesized compounds was confirmed via melting points, elemental analyses, and different spectroscopic techniques ... anticancer potential. Our results showed that, diazepine (3a) and oxazepine (4a) offered the highest binding energy against the target OMPA/ exo‑1,3‑beta‑glucanase proteins and exhibited the potent

Entropy for q-rung linear diophantine fuzzy hypersoft set with its application in MADM

A notable advancement in fuzzy set theory is the q-rung linear diophantine fuzzy set. The soft set theory was expanded into the hypersoft set theory. By combining both the q-rung linear diophantine ... . 5, 1050–1061 (2020). 37. Liu, L. et al. Entropy-based glds method for social capital selection of a ppp project with q-rung orthopair fuzzy information. Entropy 22, 414 (2020). 38. Gül, S. & Aydoğdu

Design, synthesis and in vitro anticancer activity of some new lomefloxacin derivatives

position 3 and 7 were synthesized and screened for cytotoxic activity utilizing 60 different human cancer cell lines. Furthermore, compounds 3a,b,c,e that revealed potent broad-spectrum anticancer activity ... arrest at the G2-M phase. Moreover, the mechanism of action was determined by determining the topoisomerase inhibitory activity and the molecular modeling study. Compounds 3a,b,c,e showed broad spectrum

Antibody and antibody fragments site-specific conjugation using new Q-tag substrate of bacterial transglutaminase

antibody fragments such as Fab, scfv and VHH for which random and chemical conjugation showed significant limitations. In this study, we identified a novel small peptide substrate (Q-tag) with high affinity ... , France 4 These authors contributed ARTICLE During the last few years Antibody-Drug Conjugates (ADCs) have become one of the most active and very promising therapeutic weapons. Lessons learned from the

A novel group decision making method based on CoCoSo and interval-valued Q-rung orthopair fuzzy sets

Interval-valued q-rung orthopair fuzzy set (IVq-ROFS) is a powerful tool for dealing with uncertainty. In this paper, we first propose a new method for aggregating multiple IVq-ROFSs, which is easier ... , FFS. Similarly, interval valued q-rung orthopair fuzzy set (IVq-ROFS)22 was proposed, and when the IVqROFS will degenerate to IVIFS, IVPFS, IVFFS. Compared with IVIFS, IVPFS, IVFFS, and IVq-ROFS have

Multi-level deep Q-networks for Bitcoin trading strategies

trades. In this study, we propose a multi-level deep Q-network (M-DQN) that leverages historical Bitcoin price data and Twitter sentiment analysis. In addition, an innovative preprocessing pipeline is ... . Eng . 47 , 1 - 17 ( 2021 ). 22. Xia , P. , Ni , Z. , Zhu , X. , He , Q. & Chen , Q. A novel prediction model based on long short-term memory optimised by dynamic evolutionary glowworm swarm optimisation

A novel probabilistic q-rung orthopair linguistic neutrosophic information-based method for rating nanoparticles in various sectors

The idea of probabilistic q-rung orthopair linguistic neutrosophic (P-QROLN) is one of the very few reliable tools in computational intelligence. This paper explores a significant breakthrough in ... method for solving decision-making issues in which the alternatives and criteria are assessed in a Q-RLNs environment. The authors introduce several Q-RLNs weighted aggregation operators. The properties

Knockdown of circ-Gatad1 alleviates LPS induced HK2 cell injury via targeting miR-22-3p/TRPM7 axis in septic acute kidney

apoptosis, proliferation ability, ROS and inflammatory cytokines level. Bioinformatics and luciferase report analysis confirmed that both miR-22-3p and TRPM7 were downstream targets of circ-Gatad1 ... luciferase reporter analysis confirmed that miR-22-3p inhibited luciferase activity in wild-type cells, but not in mutated cell lines (Fig. 3A and B), suggesting that miR-22-3p was the target of circ-Gatad1

Feasibility of 3D-EIT in identifying lung perfusion defect and V/Q mismatch in a patient with VA-ECMO

3D-EIT has been used to assess regional lung perfusion and ventilation/perfusion (V/Q) mismatch in an animal study [1]. In patients under extracorporeal membrane oxygenation (ECMO) therapy, bedside ... /perfusion (V/Q) image of EIT in coronary, sagittal, and axial planes demonstrating the regional V/Q distribution. Regions of dead space (high ventilation and low perfusion) are shown in dark gray. Shunt

Applying Q-methodology to investigate computer science teachers’ preferences about students’ skills and knowledge for obtaining a degree

influence learning outcomes and teaching methodologies. Acquiring hard skills and professional skills has outstanding significance in preparing students for their future careers. This study uses Q-methodology ... towards students. Similar surveys using the Q-methodology among members of the faculty have not yet been found in the field of CS. We found striking novelties among the results. Our aim was to investigate

Q&A with Bill Hurliman

. Unbeknownst to most of those he works with, Hurliman retired in 2017 as a beard and mustache national champion. Q: WHEN DID YOUR INTEREST IN BEARD GROOMING BEGIN? A: I think it goes back to middle school. It ... was a constant shaving thing … I’d have a 5 o’clock shadow by noon. Then, No Shave November was always an excuse for me to let it go. Eventually, it was just easier not shaving. Q: FAIR ENOUGH. BUT

Reliability and validity of self-report questions for assessing levels of physical activity and sedentary time in adult childhood cancer survivors

of physical activity (BHW-Q), including two questions: one on vigorous physical activity (BHW-Q VPA) and one on moderate physical activity (BHW-Q MPA). Furthermore, a single-item question was developed ... developed to measure sedentary time (SEDGIH-Q). These questions are recommended for clinical practice and have been found valid for the general population but have so far not been tested in adult childhood

Opioid-free anesthesia with ultrasound-guided quadratus lumborum block in the supine position for lower abdominal or pelvic surgery: a randomized controlled trial

Hospital of Wanning between March 2021 and July 2022 were selected and divided into a quadratus lumborum block group (Q) (n = 62) and control group (C) (n = 60) according to the random number table method ... performed via the ultrasound guided anterior approach based on images resembling a “human eye” and “baby in a cradle” under local anesthesia according to the needs of the operative field. In group Q, 20 ml of

Causal effects of glycemic traits and endometriosis: a bidirectional and multivariate mendelian randomization study

conducted. The risk of endometriosis was significantly increased by genetically predicted T1DM (OR = 1.02, 95% CI 1.00-1.04, p = 0.0171, q = 0.0556) and GDM (OR = 1.01, 95% CI 1.01–1.02, p = 1.34 × 10− 8, q ... ). Endometriosis had a suggestive association with HbA1c (Beta = 0.04, 95% CI 0.00-0.08, p = 0.0481, q = 0.1251). Using multivariate Mendelian randomization (MVMR), a significant causal effect of FI on genetically

In vitro construction of the COQ metabolon unveils the molecular determinants of coenzyme Q biosynthesis

. In animals, biosynthesis of coenzyme Q is currently attributed to ten different proteins, with COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9 forming the iconic COQ metabolon. Yet several reaction steps ... authors 6 Callum R. Nicoll 7 María Laura Mascotti 8 Domiziana Cecchini Metabolons are protein assemblies that perform a series of reactions in a metabolic pathway. However, the general importance and