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Search: authors:"A. Amado"

5 papers found.
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Coupled fermion–kink system in Jackiw–Rebbi model

In this paper, we study Jackiw–Rebbi model, in which a massless fermion is coupled to the kink of \(\lambda \phi ^4\) theory through a Yukawa interaction. In the original Jackiw–Rebbi model, the soliton is prescribed. However, we are interested in the back-reaction of the fermion on the soliton besides the effect of the soliton on the fermion. Also, as a particular example, we ...

"Single nucleotide polymorphisms of the OPG/RANKL system genes in primary hyperparathyroidism and their relationship with bone mineral density"

Background Primary hyperparathyroidism (PHPT) affects mainly cortical bone. It is thought that parathyroid hormone (PTH) indirectly regulates the activity of osteoclasts by means of the osteoprotegerin/ligand of the receptor activator of nuclear factor-κβ (OPG/RANKL) system. Several studies have confirmed that OPG (osteoprotegerin) and RANKL (ligand of the receptor activator of ...

Genetic polymorphisms are associated with serum levels of sex hormone binding globulin in postmenopausal women

Background Estrogen activity plays a critical role in bone homeostasis. The serum levels of sex hormone binding globulin (SHBG) influence free estrogen levels and activity on target tissues. The objective of this study was to analyze the influence of common polymorphisms of the SHBG gene on serum SHBG, bone mineral density (BMD), and osteoporotic fractures. Methods Four biallelic ...

Calcium-mediated parathyroid hormone release changes in patients treated with the calcimimetic agent cinacalcet

Background. The parathyroid-calcium (Ca2+-PTH) curve expresses modulation of parathyroid hormone (PTH) secretion by the parathyroid gland as a function of changing extracellular Ca2+ concentration. Patients with hyperparathyroidism (HPT) show a rightward shift of the curve compared with controls, suggesting a reduced sensitivity of parathyroid cells to Ca2+. Increasing the ...

Pattern of distribution and cycling of SLOB, Slowpoke channel binding protein, in Drosophila

Background SLOB binds to and modulates the activity of the Drosophila Slowpoke (dSlo) calcium activated potassium channel. Recent microarray analyses demonstrated circadian cycling of slob mRNA. Results We report the mRNA and protein expression pattern of slob in Drosophila heads. slob transcript is present in the photoreceptors, optic lobe, pars intercerebralis (PI) neurons and ...