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Search: authors:"Abedelnasser Abulrob"

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Perspectives in Molecular Imaging Using Staging Biomarkers and Immunotherapies in Alzheimer’s Disease

, Canada K1A 0R6 Received 13 November 2012; Accepted 20 December 2012 Academic Editors: J.-I. Kira and E. J. Thompson Copyright © 2013 Benoît Leclerc and Abedelnasser Abulrob. This is an open access

Evaluation of brain tumor vessels specific contrast agents for glioblastoma imaging

A mouse model of glioblastoma multiforme was used to determine the accumulation of a targeted contrast agent in tumor vessels. The contrast agent, consisting of superparamagnetic iron oxide coated with dextran, was functionalized with an anti-insulin-like-growth-factor binding protein 7 (anti-IGFBP7) single domain antibody. The near infrared marker, Cy5.5, was also attached for...