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16 papers found.
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Termination of pregnancy and sterilisation in women with childhood-onset type 1 diabetes

Aims/hypothesis The aim of this study was to explore the association between type 1 diabetes and reproductive health indicators in women, focusing on termination of pregnancy and sterilisation. Methods We conducted a registry-based cohort study involving 2281 women with childhood-onset type 1 diabetes, matched for age and birthplace with women without diabetes: two control...

Gestational Diabetes Mellitus Can Be Prevented by Lifestyle Intervention: The Finnish Gestational Diabetes Prevention Study (RADIEL): A Randomized Controlled Trial

Saila B. Koivusalo 8 Kristiina Ro¨no¨ 8 Miira M. Klemetti 6 7 Risto P. Roine 11 12 13 Jaana Lindstro¨m 10 Maijaliisa Erkkola 15 Risto J. Kaaja 14 Maritta Po¨yho¨nen-Alho 9 Aila Tiitinen 4 Emilia Huvinen

Periodontal disease-associated micro-organisms in peri-menopausal and post-menopausal women using or not using hormone replacement therapy. A two-year follow-up study

Background Despite conflicting results on the use of hormone replacement therapy (HRT) there is no doubt that many women benefit from it. Women using HRT are known to be more health conscious in general with putative positive implications in the mouth. However, we observed recently in our cohort hardly any difference in oral health status between HRT-users and non-users. There...

Interruption of CXCL13-CXCR5 Axis Increases Upper Genital Tract Pathology and Activation of NKT Cells following Chlamydial Genital Infection

I. Champion Archana Khurana Guangchao Liu Amanda Freed Jolein Pleijster Nora Rozengurt Jolande A. Land Helja-Marja Surcel Aila' Tiitinen Jorma Paavonen Mitchell Kronenberg Servaas A. Morre Kathleen A

Treatment for cervical intraepithelial neoplasia and subsequent IVF deliveries

BACKGROUND The aim was to study whether the treatment of cervical intraepithelial neoplasia (CIN) is associated with a subsequent increase in the use of IVF to achieve deliveries and whether women with cervical treatment and IVF have increased rates of preterm delivery. METHODS This was a register-based retrospective cohort (n = 822 183 deliveries) study from Finland whose main...

High and low BMI increase the risk of miscarriage after IVF/ICSI and FET

BACKGROUND The extremes of BMI are associated with an increased risk of miscarriage both in spontaneously conceived pregnancies and after fertility treatment. The aim of the present study was to study the effect of BMI on miscarriage rate (MR) in fresh IVF/ICSI, and in spontaneous and hormonally substituted frozen-thawed embryo (FET) cycles. METHODS Analysis was carried out on...

Clinical cure of severe, early onset preeclampsia with low molecular weight heparin therapy in primigravida with hyperreactio luteinalis and thrombophilia

Tiitinen 0 Veli-Matti Ulander 0 Risto Kaaja 0 0 Department of Obstetrics and Gynaecology, Helsinki University Central Hospital , PO Box 140, FIN-00290 HUS Helsinki , Finland 1To whom correspondence should

A Systematic Evaluation of Factors Associated With Nocturia—The Population-based FINNO Study

and Gynecology, Helsinki University Central Hospital, Helsinki, Finland (Aila Tiitinen); Department of Pulmonary Diseases, Tampere University Hospital, Tampere, Finland (Olli Polo); Department of

Early cleavage predicts the viability of human embryos in elective single embryo transfer procedures

BACKGROUND: The reduction of multiple pregnancies by using elective single embryo transfers (eSET) requires critical and careful selection of the embryo for transfer. The current study was undertaken to assess whether early cleavage could be used as a marker of embryo competence in eSET procedures. METHODS: The study included analysis of 178 eSET procedures. All embryos were...

Obstetric and perinatal outcome after oocyte donation: comparison with in-vitro fertilization pregnancies

The obstetric and perinatal outcome in 51 oocyte donation pregnancies (61 infants) was compared with that of a control group of standard in-vitro fertilization (IVF) patients (97 pregnancies, 126 infants). The oocyte recipients (mean ± SD age 33.5 ± 4.7 years) included 39 women with ovarian failure and 12 women with functioning ovaries. In oocyte recipients, first trimester...

Pregnancies after oocyte donation in women with ovarian failure caused by an inactivating mutation in the follicle stimulating hormone receptor

BACKGROUND: An inactivating point mutation (Ala189Val) in the FSH receptor (FSHR) causes primary ovarian failure. It has not been known if FSH action is necessary during pregnancy and childbirth. METHODS: In 1991–2001, donated oocytes were used to treat the infertility of 12 women with ovarian failure due to this mutation. RESULTS: When 30 fresh and 15 frozen-thawed embryo...

The predictive value of pronuclear morphology of zygotes in the assessment of human embryo quality

BACKGROUND: Recent studies have shown that zygote morphology could be used for the assessment of human embryo quality. Pronuclear (PN) morphology is based on certain distinct features seen in zygotes 16–18 h after fertilization. In the present study PN stage morphology was assessed and combined with a single embryo transfer in order to investigate whether currently used zygote...

One versus two embryo transfer after IVF and ICSI: a randomized study

BACKGROUND: The main reason for adverse treatment outcome in assisted reproduction is the high rate of multiple pregnancies. The only strategy to avoid dizygotic twins is to transfer one embryo at a time. METHODS: A total of 144 women, who had had at least four good quality embryos available after IVF/intracytoplasmic sperm injection (ICSI) and who had no more than one previous...