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Genetics of vegetarianism: A genome-wide association study

Kingdom) as Author Contributions Conceptualization: Nabeel R. Yaseen, Akiko Takeda. Data curation: Catriona L. K. Barnes, Lingwei Sun. Formal analysis: Catriona L. K. Barnes, Lingwei Sun. Funding ... , John P. Rice. Visualization: Nabeel R. Yaseen, Catriona L. K. Barnes. Writing – original draft: Nabeel R. Yaseen. Writing – review & editing: Catriona L. K. Barnes, Lingwei Sun, Akiko Takeda, John P

Comparison of serum and plasma as a source of blood extracellular vesicles: Increased levels of platelet-derived particles in serum extracellular vesicle fractions alter content profiles from plasma extracellular vesicle fractions

acquisition: Toshihide Takeuchi, Hideki Mochizuki, Yoshitaka Nagai. Investigation: Xiaoman Zhang, Akiko Takeda. Methodology: Xiaoman Zhang, Toshihide Takeuchi, Akiko Takeda. Project administration: Toshihide

Robust Bayesian model selection for variable clustering with the Gaussian graphical model

Variable clustering is important for explanatory analysis. However, only few dedicated methods for variable clustering with the Gaussian graphical model have been proposed. Even more severe, small insignificant partial correlations due to noise can dramatically change the clustering result when evaluating for example with the Bayesian information criteria (BIC). In this work, we...

Post-Infection Immunodeficiency Virus Control by Neutralizing Antibodies

BackgroundUnlike most acute viral infections controlled with the appearance of virus-specific neutralizing antibodies (NAbs), primary HIV infections are not met with such potent and early antibody responses. This brings into question if or how the presence of potent antibodies can contribute to primary HIV control, but protective efficacies of antiviral antibodies in primary HIV...

Dissection of the Transformation of Primary Human Hematopoietic Cells by the Oncogene NUP98-HOXA9

NUP98-HOXA9 is the prototype of a group of oncoproteins associated with acute myeloid leukemia. It consists of an N-terminal portion of NUP98 fused to the homeodomain of HOXA9 and is believed to act as an aberrant transcription factor that binds DNA through the homeodomain. Here we show that NUP98-HOXA9 can regulate transcription without binding to DNA. In order to determine the...

A Novel Protective MHC-I Haplotype Not Associated with Dominant Gag-Specific CD8+ T-Cell Responses in SIVmac239 Infection of Burmese Rhesus Macaques

Several major histocompatibility complex class I (MHC-I) alleles are associated with lower viral loads and slower disease progression in human immunodeficiency virus (HIV) and simian immunodeficiency virus (SIV) infections. Immune-correlates analyses in these MHC-I-related HIV/SIV controllers would lead to elucidation of the mechanism for viral control. Viral control associated...

Dominant negative MEKK1 inhibits survival of pancreatic cancer cells

Virology (E2), Graduate School of Medicine, Chiba University, Chiba 260-8670, JapanTatsuya Hirano, Yuji Shino, Takeshi Saito, Fumitake Komoda, Yoshiyuki Okutomi, Akiko Takeda & Hiroshi Shirasawa ... Akiko Takeda in:Nature Research journals • PubMed • Google ScholarSearch for Takeshi Ishihara in:Nature Research journals • PubMed • Google ScholarSearch for Taketo Yamaguchi in:Nature Research journals

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MATZINGER, SUSAN MCCLURE, GITTA STOCKINGER, AKIKO TAKEDA, JUDY P. WAYS Basel Institute for Immunology, Grenzacherstrasse 487, Postfach, CH-4005 Basel, Switzerland Mais plus ~a change . . . SIR-In his