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Usability and Patient Preference Phase 3 Study of the Sarilumab Pen in Patients with Active Moderate-to-Severe Rheumatoid Arthritis

, MedThink SciCom, and funded by Sanofi Genzyme and Regeneron Pharmaceuticals, Inc. Disclosures. Alan Kivitz has received consulting fees from AbbVie, Boehringer Ingelheim, Novartis, Sanofi, Pfizer, Roche

Disease–Drug Interaction of Sarilumab and Simvastatin in Patients with Rheumatoid Arthritis

has received consulting fees from AbbVie, Akros, Amgen, AstraZeneca, Bristol-Myers Squibb, Janssen, Eli Lilly, Pfizer, Roche, and UCB. Inga Bodrug was an investigator for this study. Alan Kivitz has

Long-Term Safety and Efficacy of Subcutaneously Administered Tocilizumab for Adult Rheumatoid Arthritis: A Multicenter Phase 3b Long-term Extension Study

Introduction To assess the long-term safety and efficacy of subcutaneous tocilizumab (TCZ-SC) in US patients with rheumatoid arthritis (RA) who rolled over from the two global phase 3 studies, SUMMACTA (NCT01194414) and BREVACTA (NCT1232569), into this open-label, single-arm, phase 3b study. Methods Patients continued to receive TCZ-SC 162 mg weekly or every other week or...

Disease–Drug Interaction of Sarilumab and Simvastatin in Patients with Rheumatoid Arthritis

, Janssen, Eli Lilly, Pfizer, Roche, and UCB. Inga Bodrug was an investigator for this study. Alan Kivitz has received research grants from, and holds stock in, Sanofi and Regeneron Pharmaceuticals, Inc

A Randomized Clinical Trial to Evaluate Two Doses of an Intra-Articular Injection of LMWF-5A in Adults with Pain Due to Osteoarthritis of the Knee

Objective The Low Molecular Weight Fraction of 5% human serum Albumin (LMWF-5A) is being investigated as a treatment for knee pain from osteoarthritis. Methods This was a multicenter randomized, vehicle-controlled, double-blind, parallel study designed to evaluate the safety and efficacy of two doses of an intra-articular injection of LMWF-5A. Patients with symptomatic knee...