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Palmitoylethanolamide in the Treatment of Failed Back Surgery Syndrome

Introduction. This observational study was designed to evaluate the efficacy of ultramicronized palmitoylethanolamide (um-PEA) (NormastĀ®) administration, as add-on therapy for chronic pain, in the management of pain-resistant patients affected by failed back surgery syndrome. Methods. A total of 35 patients were treated with tapentadol (TPD) and pregabalin (PGB). One month after...

Pain as a First Manifestation of Paraneoplastic Neuropathies: A Systematic Review and Meta-Analysis

literature review and wrote the manuscript. Antonella Paladini, Alba Piroli, Patrick C. McHugh, Giustino Varrassi, and Marios Hadjivassiliou revised and critically appraised the manuscript. Disclosures ... . Panagiotis Zis, Antonella Paladini, Alba Piroli, Patrick C. McHugh, Giustino Varrassi and Marios Hadjivassiliou have nothing to disclose. Compliance with Ethics Guidelines. This article is based on previously