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The Health and Environment Network and its achievements

Alena Bartonova 0 Janna G Koppe Aleksandra Fucic Arno C Gutleb Peter van den Hazel Hans Keune 0 NILU - Norwegian Institute for Air Research , Kjeller , Norway In the HENVINET project, the four

Cancer risk and the complexity of the interactions between environmental and host factors: HENVINET interactive diagrams as simple tools for exploring and understanding the scientific evidence

Background Development of graphical/visual presentations of cancer etiology caused by environmental stressors is a process that requires combining the complex biological interactions between xenobiotics in living and occupational environment with genes (gene-environment interaction) and genomic and non-genomic based disease specific mechanisms in living organisms. Traditionally...

Environmental exposure to xenoestrogens and oestrogen related cancers: reproductive system, breast, lung, kidney, pancreas, and brain

The role of steroids in carcinogenesis has become a major concern in environmental protection, biomonitoring, and clinical research. Although historically oestrogen has been related to development of reproductive system, research over the last decade has confirmed its crucial role in the development and homeostasis of other organ systems. As a number of anthropogenic agents are...

Automated image analysis of cytokinesis-blocked micronuclei: an adapted protocol and a validated scoring procedure for biomonitoring

Micronuclei (MN) frequencies in peripheral blood lymphocytes have been used worldwide as a biomarker of chromosomal damage for genotoxicity testing and biomonitoring studies. Automation of MN analysis would provide faster and more reliable results with minimizing subjective MN identification. We developed an automated facility for the scoring of the in vitro MN cytokinesis-block...

Chromosomal Aberrations and Cancer Risk: Results of a Cohort Study from Central Europe

Paolo Boffetta ) 6 Olga van der Hel 6 Hannu Norppa 5 Eleonora Fabianova 4 Aleksandra Fucic 11 Sarolta Gundy 10 Juozas Lazutka 9 Antonina Cebulska-Wasilewska 8 13 Daniela Puskailerova 4 Ariana Znaor