Isar, Technical University of Munich, Ismaninger Str. 22, 81675, Munich, Germany Felix G. Gassert, Florian T. Gassert, Marcus R. Makowski, Alexandra S. Gersing & Klaus Woertler Department of Pathology ... search for this author in PubMed Google Scholar Alexandra S. Gersing View author publications You can also search for this author in PubMed Google Scholar Klaus Woertler View author publications
Osteoporosis remains under-diagnosed, which may be improved by opportunistic bone mineral density (BMD) measurements on CT. However, correcting for the influence of intravenous iodine-based contrast agent is challenging. The purpose of this study was to assess the diagnostic accuracy of iodine-corrected vertebral BMD measurements derived from non-dedicated contrast-enhanced...
To evaluate the performance of 3D T1w spoiled gradient-echo (T1SGRE) and ultra-short echo time (UTE) MRI sequences for the detection and assessment of vertebral fractures and degenerative bone changes compared with conventional CT. Fractures (n = 44) and degenerative changes (n = 60 spinal segments) were evaluated in 30 patients (65 ± 14 years, 18 women) on CT and 3-T MRI...
To evaluate the diagnostic value of MR imaging for the differentiation of lipomas and atypical lipomatous tumors (ALT) in comparison with histology and MDM2 amplification status. Patients with well-differentiated lipomatous tumors (n = 113), of which 66 were diagnosed as lipoma (mean age 53 years (range, 13–82); 47% women) and 47 as atypical lipomatous tumor (ALT; mean age 60...
. Schwaiger and Alexandra S. Gersing contributed equally to this work. * caused by osteoporosis [ 1 ], but also in otherwise healthy patients after adequate trauma. With a prevalence of up to 26% in women and ... , performed the statistical analysis, and drafted the manuscript. Alexandra S. Gersing assisted with the study design, collected the data, performed the reading of the images, helped interpret the data, and
ObjectiveTo investigate the in vivo applicability of non-contrast-enhanced hydroxyapatite (HA)-specific bone mineral density (BMD) measurements based on dual-layer CT (DLCT).MethodsA spine phantom containing three artificial vertebral bodies with known HA densities was measured to obtain spectral data using DLCT and quantitative CT (QCT), simulating different patient positions...
After reperfusion therapy in stroke patients secondary inflammatory processes may increase cerebral damage. In this pilot study, effects of anti-inflammatory therapy were assessed in a middle cerebral artery occlusion (MCAO) mouse model after reperfusion. 1 hour after MCAO, the artery was reopened and tacrolimus or NaCl were administered intra-arterially. Perfusion-weighted (PWI...
Alexandra S. Gersing Jan S. Kirschke Daniela Muenzel Alexander A. Fingerle Ernst J. Rummeny Franz Pfeiffer Thomas Baum Peter B. Noël OPEN Published: xx xx xxxx To assess whether phantomless calcium
Background Anterior cruciate ligaments (ACL) injuries represent a major risk factor for early osteoarthritis (OA). Purpose To evaluate the prevalence and 4-year progression of knee OA measured with 3T MR-imaging in individuals with ruptured, reconstructed or normal ACL and to assess the impact of thigh muscle characteristics. Methods A total of 54 knees (23/54 male, 31/54 female...
Objective Osteoporosis diagnosis using multidetector CT (MDCT) is limited to relatively high radiation exposure. We investigated the effect of simulated ultra-low-dose protocols on in-vivo bone mineral density (BMD) and quantitative trabecular bone assessment. Materials and methods Institutional review board approval was obtained. Twelve subjects with osteoporotic vertebral...
