Advanced search    

Search: authors:"Ali Naderi"

9 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Effect of the size of the charged group on the properties of alkoxylated NFCs

The impact of the size of the charged group on the properties of alkoxylated NFC was studied by two chloroalkyl acid reagents. It was found that the employment of the larger 2-chloropropionic acid reagent leads to improved properties, e.g. higher fraction of nano-sized materials, and significantly better redispersion as compared to when the smaller monochloroacetic acid was ...

Prolactin-induced protein mediates cell invasion and regulates integrin signaling in estrogen receptor-negative breast cancer

Introduction Molecular apocrine is a subtype of estrogen receptor (ER)-negative breast cancer that is characterized by a steroid-response gene signature. We have recently identified a positive feedback loop between androgen receptor (AR) and extracellular signal-regulated kinase (ERK) signaling in this subtype. In this study, we investigated the transcriptional regulation of ...

Synergy between inhibitors of androgen receptor and MEK has therapeutic implications in estrogen receptor-negative breast cancer

inhibitors of androgen and MEK has therapeutic implications in receptor-negative breast cancer Naderi et al. receptor estrogen Open Access Ali Naderi*, Kee Ming Chia and Ji Liu Introduction Estrogen receptor

BEX2 has a functional interplay with c-Jun/JNK and p65/RelA in breast cancer

Background We have previously demonstrated that BEX2 is differentially expressed in breast tumors and has a significant role in promoting cell survival and growth in breast cancer cells. BEX2 expression protects breast cancer cells against mitochondrial apoptosis and G1 cell cycle arrest. In this study we investigated the transcriptional regulation of BEX2 and feedback mechanisms ...

Effect of opium addiction on new and traditional cardiovascular risk factors: do duration of addiction and route of administration matter?

Background There is a belief among some society that opium has a number of beneficial effects on cardiovascular disease. The aim of the present investigation as a cross-sectional study was to assess this hypothesis. Several biochemical factors (Fasting blood sugar, Cholesterol, Triglyceride, LDL-Cholesterol, HDL-Cholesterol, HbA1C, CRP, Fibrinogen, Factor VII, SGOT, SGPT, Lpa, apo ...

PACK: Profile Analysis using Clustering and Kurtosis to find molecular classifiers in cancer

Motivation: Elucidating the molecular taxonomy of cancers and finding biological and clinical markers from microarray experiments is problematic due to the large number of variables being measured. Feature selection methods that can identify relevant classifiers or that can remove likely false positives prior to supervised analysis are therefore desirable. Results: We present a ...

Expression microarray reproducibility is improved by optimising purification steps in RNA amplification and labelling

Background Expression microarrays have evolved into a powerful tool with great potential for clinical application and therefore reliability of data is essential. RNA amplification is used when the amount of starting material is scarce, as is frequently the case with clinical samples. Purification steps are critical in RNA amplification and labelling protocols, and there is a lack ...

A consensus prognostic gene expression classifier for ER positive breast cancer

Background A consensus prognostic gene expression classifier is still elusive in heterogeneous diseases such as breast cancer. Results Here we perform a combined analysis of three major breast cancer microarray data sets to hone in on a universally valid prognostic molecular classifier in estrogen receptor (ER) positive tumors. Using a recently developed robust measure of ...