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12 papers found.
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Effects of nitroglycerine on coronary flow velocity before and during adenosine provocation

Background Transthoracic echocardiography-assessed coronary flow velocity reserve (CFVR) evaluates coronary microvascular arterial function. Coronary flow velocity measurements at baseline and during hyperemia are used to calculate CFVR. Adenosine infusion induces hyperemia but it is not known if it causes a maximal response. We hypothesized that pre-treatment with nitroglycerine...

Effects of nitroglycerine on coronary flow velocity before and during adenosine provocation

Background Transthoracic echocardiography-assessed coronary flow velocity reserve (CFVR) evaluates coronary microvascular arterial function. Coronary flow velocity measurements at baseline and during hyperemia are used to calculate CFVR. Adenosine infusion induces hyperemia but it is not known if it causes a maximal response. We hypothesized that pre-treatment with nitroglycerine...

The Arachidonate 15-Lipoxygenase Enzyme Product 15-HETE Is Present in Heart Tissue from Patients with Ischemic Heart Disease and Enhances Clot Formation

Ischemic heart disease is a major cause of death and morbidity and the search for novel therapeutic targets is still required. We have previously shown that the enzyme arachidonate 15 lipoxygenase (ALOX15), which catalyzes the conversion of arachidonic acid to 15-hydroxy eicosatetraenoic acid (15-HETE), is highly expressed in ischemic heart tissue, but its role in the...

Re-interventions after endovascular aortic repair for infrarenal abdominal aneurysms: a retrospective cohort study

Background Early morbidity and mortality are generally lower after endovascular aortic repair (EVAR), than after open repair but re-interventions and late complications are more common. The aim of the present study was to make a detailed description of re-interventions after EVAR-including incidence, indications, procedures, and outcome-with special reference to non-access...

Transfusions and blood loss in total hip and knee arthroplasty: a prospective observational study

Background There is a high prevalence of blood product transfusions in orthopedic surgery. The reported prevalence of red blood cell transfusions in unselected patients undergoing hip or knee replacement varies between 21% and 70%. We determined current blood loss and transfusion prevalence in total hip and knee arthroplasty when tranexamic acid was used as a routine prophylaxis...

A structured blood conservation programme reduces transfusions and costs in cardiac surgery

transfusions is necessary. This work was supported by the Swedish Heart-Lung Foundation (grant number 20090488 and 20120372 to Anders Jeppsson); and the Gteborg Medical Society (grant number 172941, 246331 and

Heparin and Protamine Titration Does Not Improve Haemostasis after Cardiac Surgery: A Prospective Randomized Study

Background Bleeding complications are common in cardiac surgery. Perioperative handling of heparin and protamine may influence the haemostasis. We hypothesized that heparin and protamine dosing based on individual titration curves would improve haemostasis in comparison to standard dosing. Subjects and Methods Sixty patients scheduled for first time elective coronary artery...

Arachidonate 15-Lipoxygenase Enzyme Products Increase Platelet Aggregation and Thrombin Generation

Atherosclerotic cardiovascular diseases are the leading causes of morbidity and mortality worldwide. We have previously shown that arachidonate 15-lipoxygenase B (ALOX15B) is highly expressed in atherosclerotic carotid plaques, and elucidation of mechanisms downstream of activated lipoxygenases may be relevant to our understanding of the genesis of atherosclerotic diseases. We...

Financial priorities under decentralization in Uganda

ANDERS JEPPSSON Ministry of Health Kampala Uganda This paper explores changes to budget allocations for health during the decentralization process in Uganda. When the districts were given the ... views on the manuscript. Anders Jeppsson is a physician with training and experience in public health, health policy development, health sector reform and health services management, currently working as

Restructuring a ministry of health – an issue of structure and process: a case study from Uganda

reviewers for invaluable comments on the manuscript. Biographies Anders Jeppsson, MD, MPH, MSc, is a physician, anthropologist and public health expert with more than two decades of experience in health

The policy on public–private mix in the Ugandan health sector: catching up with reality

. Anders Jeppsson is a physician with training and experience in public health, policy development, health sector reform and health services management. He is currently working as management adviser to the

Clinical Nephrology - Epidemiology II

Introduction and Aims: The Birmingham Vasculitis Activity Score (BVAS) correlates closely with disease activity in patients with ANCA associated vasculitis, however, conflicting results have been reported about its association with mortality. In this retrospective cohort study we assessed if BVAS at the time of diagnosis predicts mortality in a group of consecutive patients with...