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Plasmodium vivax Landscape in Brazil: Scenario and Challenges

sustained and progressive control actions in this Latin American region. Received March 14, 2016. Accepted for publication August 19, 2016. Published online October 5, 2016. Authors’ addresses: Andre M ... . Siqueira, Instituto Nacional de Infectologia, Fundacao Oswaldo Cruz (Fiocruz), Rio de Janeiro, Brazil, E-mail: . Oscar Mesones-Lapouble, Pan American Health Organization, Brasilia, Brazil, E-mail: oscar

Fixed-Dose Artesunate–Amodiaquine Combination vs Chloroquine for Treatment of Uncomplicated Blood Stage P. vivax Infection in the Brazilian Amazon: An Open-Label Randomized, Controlled Trial

Background. Despite increasing evidence of the development of Plasmodium vivax chloroquine (CQ) resistance, there have been no trials comparing its efficacy with that of artemisinin-based combination therapies (ACTs) in Latin America.