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Epilithic Chamaesiphon (Synechococcales, Cyanobacteria) species in mountain streams of the Alps—interspecific differences in photo-physiological traits

Many alpine streams inhabit conspicuous epilithic biofilms on pebbles and rocks that are formed by members of the cyanobacterial genus Chamaesiphon (Synechococcales). In the Austrian Alps, some Chamaesiphon species can even overgrow up to 70% of the surface of river rocks, and hence they must play an important but still unstudied ecological role in the organic matter flux. Since...

Interactive machine learning for health informatics: when do we need the human-in-the-loop?

changes were made. Andreas Holzinger is lead of the Holzinger Group, head of the Research Unit HCI-KDD at the Institute for Medical Informatics, Statistics and Documentation at the Medical University Graz

Single colony genetic analysis of epilithic stream algae of the genus Chamaesiphon spp.

In order to understand Chamaesiphon spp. evolution and ecological diversification, we investigated the phylogenetic differentiation of three morphospecies from field samples by means of single colony genetics. Individual colonies of three different morphospecies (C. starmachii, C. polonicus, C. geitleri,) were isolated from lotic gravel streams and their 16S rDNA nucleotide...

Terrestrial adaptation of green algae Klebsormidium and Zygnema (Charophyta) involves diversity in photosynthetic traits but not in CO2 acquisition

2 Department of Botany, Functional Plant Biology, University of Innsbruck , 6020 Innsbruck , Austria 3 & Andreas Holzinger 4 Abbreviations CEF-PSI Cyclic electron flow around PSI C 5 Faculty of Life

Leaf anatomy of two reciprocally non-monophyletic mountain plants (Heliosperma spp.): does heritable adaptation to divergent growing sites accompany the onset of speciation?

Evolution is driven by natural selection, favouring individuals adapted in phenotypic traits to the environmental conditions at their growing site. To shed light on ecological and (epi-) genetically based differentiation between Heliosperma pusillum and Heliosperma veselskyi, two reciprocally non-monophyletic, but morphologically and ecologically divergent species from the south...

The terrestrial green macroalga Prasiola calophylla (Trebouxiophyceae, Chlorophyta): ecophysiological performance under water-limiting conditions

The phylogenetic placement of Prasiola calophylla, from an anthropogenic habitat previously shown to contain a novel UV sunscreen compound, was confirmed by analysis of its rbcL gene. This alga has the capacity to tolerate strong water-limiting conditions. The photosynthetic performance and ultrastructural changes under desiccation and osmotic stress were investigated. Freshly...

Entransia and Hormidiella, sister lineages of Klebsormidium (Streptophyta), respond differently to light, temperature, and desiccation stress

The green-algal class Klebsormidiophyceae (Streptophyta), which occurs worldwide, comprises the genera Klebsormidium, Interfilum, Entransia, and Hormidiella. Ecophysiological research has so far focused on the first two genera because they are abundant in biological soil crust communities. The present study investigated the photosynthetic performances of Hormidiella attenuata and...

A tamper-proof audit and control system for the doctor in the loop

editorial board of Computers & Security (COSE), ), organizes the ARES conference and is General Chair of SACMAT 2015, PC Chair of Esorics 2015 and General Chair of ACM CCS 2016. Andreas Holzinger is the lead

Green algae in alpine biological soil crust communities: acclimation strategies against ultraviolet radiation and dehydration

Green algae are major components of biological soil crusts in alpine habitats. Together with cyanobacteria, fungi and lichens, green algae form a pioneer community important for the organisms that will succeed them. In their high altitudinal habitat these algae are exposed to harsh and strongly fluctuating environmental conditions, mainly intense irradiation, including...

Integrated web visualizations for protein-protein interaction databases

Background Understanding living systems is crucial for curing diseases. To achieve this task we have to understand biological networks based on protein-protein interactions. Bioinformatics has come up with a great amount of databases and tools that support analysts in exploring protein-protein interactions on an integrated level for knowledge discovery. They provide predictions...

Prasiolin, a new UV-sunscreen compound in the terrestrial green macroalga Prasiola calophylla (Carmichael ex Greville) Kützing (Trebouxiophyceae, Chlorophyta)

-tolerant organisms. Author contributions statement Anja Hartmann: undertook all practical experiments, processed the data, prepared most figures and table, edited the manuscript; Andreas Holzinger

KNODWAT: A scientific framework application for testing knowledge discovery methods for the biomedical domain

Background Professionals in the biomedical domain are confronted with an increasing mass of data. Developing methods to assist professional end users in the field of Knowledge Discovery to identify, extract, visualize and understand useful information from these huge amounts of data is a huge challenge. However, there are so many diverse methods and methodologies available, that...

Nitrogen Limitation and Slow Drying Induce Desiccation Tolerance in Conjugating Green Algae (Zygnematophyceae, Streptophyta) from Polar Habitats

Background Filamentous Zygnematophyceae are typical components of algal mats in the polar hydro-terrestrial environment. Under field conditions, they form senescent vegetative cells, designated as pre-akinetes, which are tolerant to desiccation and osmotic stress. Key Findings Pre-akinete formation and desiccation tolerance was investigated experimentally under monitored...

An adaptive annotation approach for biomedical entity and relation recognition

Eastern Slavonia Region. He has published 4 papers as a co-author, and his doctoral work on using electronic health records for research purposes is at the final stage of completion. Andreas Holzinger is

Interactive knowledge discovery with the doctor-in-the-loop: a practical example of cerebral aneurysms research

intracranial vessels. Andreas Holzinger is the head of the Holzinger Group, HCI-KDD, at the Institute of Medical Informatics, Statistics and Documentation at the Medical University Graz, and an Assoc.Prof. of

Desiccation tolerance in the chlorophyte green alga Ulva compressa: does cell wall architecture contribute to ecological success?

Main conclusion Desiccation leads to structural changes of the inner pectic cell wall layers in Ulva compressa . This contributes to protection against mechanical damage due to desiccation–rehydration cycles. Ulva compressa, characterized by rbcL phylogeny, is a common species in the Mediterranean Sea. Ulva as an intertidal species tolerates repeated desiccation–rehydration...

Knowledge Discovery and interactive Data Mining in Bioinformatics - State-of-the-Art, future challenges and research directions

, inaccurate, but brilliant. Together they may be powerful beyond imagination. Authors information Andreas Holzinger is head of the Research Unit Human-Computer Interaction, Institute for Medical Informatics at

Visual analytics for concept exploration in subspaces of patient groups

International Network since 2010. Andreas Holzinger and his Group work on extracting knowledge from data and foster a synergistic combination of methodologies of two areas that offer ideal conditions towards