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Search: authors:"Angela Ariza de Schellenberger"

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Novel magnetic multicore nanoparticles designed for MPI and other biomedical applications: From synthesis to first in vivo studies

). Author Contributions Conceptualization: Harald Kratz. Funding acquisition: Matthias Taupitz, Lutz Trahms, Bernd Hamm, JoÈrg Schnorr. Investigation: Harald Kratz, Angela Ariza de Schellenberger, Olaf ... Kosch, Dietmar Eberbeck, JoÈrg Schnorr. Methodology: Harald Kratz, Angela Ariza de Schellenberger, Olaf Kosch, Dietmar Eberbeck, Susanne Wagner, JoÈrg Schnorr. Project administration: JoÈrg Schnorr

XTEN as Biological Alternative to PEGylation Allows Complete Expression of a Protease-Activatable Killin-Based Cytostatic

Increased effectiveness and reduced side effects are general goals in drug research, especially important in cancer therapy. The aim of this study was to design a long-circulating, activatable cytostatic drug that is completely producible in E. coli. Crucial for this goal was the novel unstructured polypeptide XTEN, which acts like polyethylene glycol (PEG) but has many important ...