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Search: authors:"Angela Ariza de Schellenberger"

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Novel magnetic multicore nanoparticles designed for MPI and other biomedical applications: From synthesis to first in vivo studies

). Author Contributions Conceptualization: Harald Kratz. Funding acquisition: Matthias Taupitz, Lutz Trahms, Bernd Hamm, JoÈrg Schnorr. Investigation: Harald Kratz, Angela Ariza de Schellenberger, Olaf ... Kosch, Dietmar Eberbeck, JoÈrg Schnorr. Methodology: Harald Kratz, Angela Ariza de Schellenberger, Olaf Kosch, Dietmar Eberbeck, Susanne Wagner, JoÈrg Schnorr. Project administration: JoÈrg Schnorr

XTEN as Biological Alternative to PEGylation Allows Complete Expression of a Protease-Activatable Killin-Based Cytostatic

Increased effectiveness and reduced side effects are general goals in drug research, especially important in cancer therapy. The aim of this study was to design a long-circulating, activatable cytostatic drug that is completely producible in E. coli. Crucial for this goal was the novel unstructured polypeptide XTEN, which acts like polyethylene glycol (PEG) but has many important...