Advanced search    

Search: authors:"Angela Huttner"

6 papers found.
Use AND, OR, NOT, +word, -word, "long phrase", (parentheses) to fine-tune your search.

Antimicrobial resistance: a global view from the 2013 World Healthcare-Associated Infections Forum

Angela Huttner 0 Stephan Harbarth 0 Jean Carlet Sara Cosgrove Herman Goossens Alison Holmes Vincent Jarlier Andreas Voss Didier Pittet 0 for the World Healthcare-Associated Infections Forum

Volunteer feedback and perceptions after participation in a phase I, first-in-human Ebola vaccine trial: An anonymous survey

The continued participation of volunteers in clinical trials is crucial to advances in healthcare. Few data are available regarding the satisfaction and impressions of healthy volunteers after participation in phase I trials, many of which lead to unexpected adverse events. We report feedback from over 100 adult volunteers who took part in a first-in-human trial conducted in a...

An Economic Analysis of Strategies to Control Clostridium Difficile Transmission and Infection Using an Agent-Based Simulation Model

Background A number of strategies exist to reduce Clostridium difficile (C. difficile) transmission. We conducted an economic evaluation of “bundling” these strategies together. Methods We constructed an agent-based computer simulation of nosocomial C. difficile transmission and infection in a hospital setting. This model included the following components: interactions between...

Assisted Knowledge Discovery for the Maintenance of Clinical Guidelines

Background Improving antibiotic prescribing practices is an important public-health priority given the widespread antimicrobial resistance. Establishing clinical practice guidelines is crucial to this effort, but their development is a complex task and their quality is directly related to the methodology and source of knowledge used. Objective We present the design and the...

A Simulation-Based Assessment of Strategies to Control Clostridium Difficile Transmission and Infection

Background Clostridium difficile is one of the most common and important nosocomial pathogens, causing severe gastrointestinal disease in hospitalized patients. Although "bundled" interventions have been proposed and promoted, optimal control strategies remain unknown. Methods We designed an agent-based computer simulation of nosocomial C. difficile transmission and infection...