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Ligand-Doped Copper Oxo-hydroxide Nanoparticles are Effective Antimicrobials

Fund project TK134 (Angela Ivask), and PUT1015 (Olesja Bondarenko) are acknowledged. Availability of Data and Materials Raw data and materials are available on reasonable request. Authors’ Contributions

A Molecular Probe for the Detection of Polar Lipids in Live Cells

Lipids have an important role in many aspects of cell biology, including membrane architecture/compartment formation, intracellular traffic, signalling, hormone regulation, inflammation, energy storage and metabolism. Lipid biology is therefore integrally involved in major human diseases, including metabolic disorders, neurodegenerative diseases, obesity, heart disease, immune...

Particle-Cell Contact Enhances Antibacterial Activity of Silver Nanoparticles

Background It is generally accepted that antibacterial properties of Ag nanoparticles (AgNPs) are dictated by their dissolved fraction. However, dissolution-based concept alone does not fully explain the toxic potency of nanoparticulate silver compared to silver ions. Methodology/Principal Findings Herein, we demonstrated that the direct contact between bacterial cell and AgNPs...

Toxicity of Ag, CuO and ZnO nanoparticles to selected environmentally relevant test organisms and mammalian cells in vitro: a critical review

Nanoparticles (NPs) of copper oxide (CuO), zinc oxide (ZnO) and especially nanosilver are intentionally used to fight the undesirable growth of bacteria, fungi and algae. Release of these NPs from consumer and household products into waste streams and further into the environment may, however, pose threat to the ‘non-target’ organisms, such as natural microbes and aquatic...

Size-Dependent Toxicity of Silver Nanoparticles to Bacteria, Yeast, Algae, Crustaceans and Mammalian Cells In Vitro

The concept of nanotechnologies is based on size-dependent properties of particles in the 1–100 nm range. However, the relation between the particle size and biological effects is still unclear. The aim of the current paper was to generate and analyse a homogenous set of experimental toxicity data on Ag nanoparticles (Ag NPs) of similar coating (citrate) but of 5 different...

A suite of recombinant luminescent bacterial strains for the quantification of bioavailable heavy metals and toxicity testing

Angela Ivask 0 Taisia Rlova 0 Anne Kahru 0 0 Address: Laboratory of Molecular Genetics, National Institute of Chemical Physics and Biophysics , Akadeemia tee 23, Tallinn , Estonia Background