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Search: authors:"Angelo R. Carpinelli"

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Short-term high glucose culture potentiates pancreatic beta cell function

Search for Laila R. Santos in:Nature Research journals • PubMed • Google Scholar Search for Angelo R. Carpinelli in:Nature Research journals • PubMed • Google Scholar Search for Patrik Rorsman in:Nature

Pancreatic β-Cells Express Phagocyte-Like NAD(P)H Oxidase

The presence of a phagocyte-like NAD(P)H oxidase in pancreatic β-cells was investigated. Three NAD(P)H oxidase components were found in pancreatic islets by RT-PCR: gp91PHOX, p22PHOX, and p47PHOX. The components p67PHOX and p47PHOX were also demonstrated by Western blotting. Through immunohistochemistry, p47PHOX was mainly found in the central area of the islet, confirming the...