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5 papers found.
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Tumor-infiltrating lymphocyte subsets and tertiary lymphoid structures in pulmonary metastases from colorectal cancer

The presence of tumor-infiltrating lymphocytes (TILs) and tertiary lymphoid structures (TLSs) reflects an active inflammatory tumor microenvironment. High density of TILs as well as presence of TLS is associated with improved survival in various solid cancer types. We aimed to describe the density and distribution of TILs and TLS in pulmonary metastases (PMs) from primary ...

Programmed death ligand 1 expression and tumor-infiltrating lymphocytes in glioblastoma

Background Immune checkpoint inhibitors targeting programmed cell death 1 (PD1) or its ligand (PD-L1) showed activity in several cancer types.

NRAS and BRAF Mutations in Melanoma-Associated Nevi and Uninvolved Nevi

According to the prevailing multistep model of melanoma development, oncogenic BRAF or NRAS mutations are crucial initial events in melanoma development. It is not known whether melanocytic nevi that are found in association with a melanoma are more likely to carry BRAF or NRAS mutations than uninvolved nevi. By laser microdissection we were able to selectively dissect and genotype ...

Preoperative Diffusion-Weighted Imaging of Single Brain Metastases Correlates with Patient Survival Times

. This study was performed within the PhD thesis project of Anna Sophie Berghoff in the PhD program Clinical Neuroscience (CLINS) at the Medical University Vienna. This study was performed within the

CLIN-RADIOLOGY

SURVIVAL TIMES IN PATIENTS WITH SINGLE BRAIN METASTASES Anna Sophie Berghoff 10 Department for Nuclear Medicine, Innsbruck Medical University , Innsbruck , Austria 11 RA-10. FET- AND FLT-PET RESPONSE