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Search: authors:"Anne-Laure Castell"

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The IGF1 P2 promoter is an epigenetic QTL for circulating IGF1 and human growth

Background Even if genetics play an important role, individual variation in stature remains unexplained at the molecular level. Indeed, genome-wide association study (GWAS) have revealed hundreds of variants that contribute to the variability of height but could explain only a limited part of it, and no single variant accounts for more than 0.3% of height variance. At the...