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14 papers found.
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Curcumin Modulates DNA Methyltransferase Functions in a Cellular Model of Diabetic Retinopathy

Specialties, University of Catania, Via Plebiscito 628, Catania 95124, Italy Correspondence should be addressed to Manlio Vinciguerra; zc.asunf@arreugicniv.oilnam and Antonella Agodi; ti.tcinu@aidoga Received ... /0000492). Andrea Maugeri, Martina Barchitta, and Antonella Agodi are supported by the Department of Medical and Surgical Sciences and Advanced Technologies “GF Ingrassia”, Università di Catania (Piano

Poor adherence to guidelines for preventing central line-associated bloodstream infections (CLABSI): results of a worldwide survey

Background Central line-associated bloodstream infections (CLABSI) are a cause of increased morbidity and mortality, and are largely preventable. We documented attitudes and practices in intensive care units (ICUs) in 2015 in order to assess compliance with CLABSI prevention guidelines. Methods Between June and October 2015, an online questionnaire was made available to medical...

Preventable proportion of intubation-associated pneumonia: Role of adherence to a care bundle

: Antonella Agodi, Martina Barchitta, Annalisa Quattrocchi, Francesco Auxilia, Silvio Brusaferro, Marcello Mario D'Errico, Maria Teresa Montagna, Cesira Pasquarella, Stefano Tardivo and Ida Mura. Author ... Contributions Conceptualization: Antonella Agodi. Data curation: Antonella Agodi, Martina Barchitta, Annalisa Quattrocchi, Emiliano Spera, Giovanni Gallo. Formal analysis: Martina Barchitta, Annalisa

DAPK1 Promoter Methylation and Cervical Cancer Risk: A Systematic Review and a Meta-Analysis

Objective The Death-Associated Protein Kinase 1 (DAPK1) gene has been frequently investigated in cervical cancer (CC). The aim of the present study was to carry out a systematic review and a meta-analysis in order to evaluate DAPK1 promoter methylation as an epigenetic marker for CC risk. Methods A systematic literature search was carried out. The Cochrane software package Review...

Antibiotic trends of Klebsiella pneumoniae and Acinetobacter baumannii resistance indicators in an intensive care unit of Southern Italy, 2008–2013

Background The overuse of antimicrobials is one of the main factors responsible for the development and spread of antimicrobial resistance, together with other causes, such as intra- and inter-hospital spread of resistant microorganisms and infection control policies and practices. The objective of the present study is to report the trends of Klebsiella pneumoniae and...

Low fruit consumption and folate deficiency are associated with LINE-1 hypomethylation in women of a cancer-free population

Several dietary agents, such as micronutrient and non-nutrient components, the so-called bioactive food components, have been shown to display anticancer properties and influence genetic processes. The most common epigenetic change is DNA methylation. Hypomethylation of long interspersed elements (LINE-1) has been associated with an increased risk of several cancers, although...

LINE-1 Hypomethylation in Blood and Tissue Samples as an Epigenetic Marker for Cancer Risk: A Systematic Review and Meta-Analysis

Objective A systematic review and a meta-analysis were carried out in order to summarize the current published studies and to evaluate LINE-1 hypomethylation in blood and other tissues as an epigenetic marker for cancer risk. Methods A systematic literature search in the Medline database, using PubMed, was conducted for epidemiological studies, published before March 2014. The...

Folate deficiency is not associated with increased mitochondrial genomic instability: results from dietary intake and lymphocytic mtDNA 4977-bp deletion in healthy young women in Italy

The mitochondrial DNA (mtDNA) 4977-bp deletion is a biomarker of mitochondrial genomic instability. It is frequently detected in a number of sporadic diseases, and it accumulates in many tissues during aging. Folic acid plays an important role in the maintenance of genomic stability in mammals. The aim of the present cross-sectional study was to characterise the levels of the...

Circulating miRNAs profiles in tourette syndrome: molecular data and clinical implications

Mariangela Gulisano 1 Paola V Calì 1 Claudio Pappalardo 4 Martina Barchitta 3 Mariagrazia Granata 4 Angelo G Condorelli 4 Davide Barbagallo 4 Marina Scalia 4 Antonella Agodi 3 Cinzia Di Pietro 4 Michele

Neutrophil counts distinguish between malignancy and arthritis in children with musculoskeletal pain: a case–control study

Background To identify the predictive factors for malignancies using basic clinical and laboratory information in children presenting with musculoskeletal pain and eventually diagnosed with juvenile idiopathic arthritis (JIA) or malignancy. Methods A retrospective case–control chart review research examining laboratory data from patients referred for musculoskeletal pain in 2001...

Knowledge about tuberculosis among undergraduate health care students in 15 Italian universities: a cross-sectional study

Tafuri 0 11 Antonella Agodi 10 Francesco Auxilia 9 Beatrice Casini 16 Maria Franca Coscia 15 Marcello Mario D'Errico 14 Margherita Ferrante 10 Angelo Fortunato 13 Cinzia Germinario 0 11 Domenico Martinelli

Prevalence of urinary colonization by extended spectrum-beta-lactamase Enterobacteriaceae among catheterised inpatients in Italian long term care facilities

Background Long Term Care Facilities (LTCFs) play a key role in guaranteeing care to patients in developed countries. Many patients, mostly elderly, access LTCFs at some time in their lives, and their healthcare pathways often require them to move back and forth between hospital and outpatient settings. These patterns bring about new challenges regarding infection control...