CD90 is a membrane GPI-anchored protein with one Ig V-type superfamily domain that was initially described in mouse T cells. Besides the specific expression pattern and functions of CD90 that were described in normal tissues, i.e., neurons, fibroblasts and T cells, increasing evidences are currently highlighting the possible involvement of CD90 in cancer. This review first...
from the DAAD Grant “DNA Damage and Repair and Their Relevance to Carcinogenesis” (No 57339330). Efstathios-Iason Vlachavas, Eleftherios Pilalis, and Aristotelis Chatziioannou acknowledge support from ... ”. Author Contributions: Aristotelis Chatziioannou, Alexandros G. Georgakilas and Constantinos E. Vorgias conceived the study. Aristotelis Chatziioannou designed and supervised the in-silico; Constantinos
Several studies have employed DNA microarrays to identify gene expression signatures that mark human ageing; yet the features underlying this complicated phenomenon remain elusive. We thus conducted a bioinformatics meta-analysis on transcriptomics data from human cell- and biopsy-based microarrays experiments studying cellular senescence or in vivo tissue ageing, respectively...
Several studies have employed DNA microarrays to identify gene expression signatures that mark human ageing; yet the features underlying this complicated phenomenon remain elusive. We thus conducted a bioinformatics meta-analysis on transcriptomics data from human cell- and biopsy-based microarrays experiments studying cellular senescence or in vivo tissue ageing, respectively...
Several studies have employed DNA microarrays to identify gene expression signatures that mark human ageing; yet the features underlying this complicated phenomenon remain elusive. We thus conducted a bioinformatics meta-analysis on transcriptomics data from human cell- and biopsy-based microarrays experiments studying cellular senescence or in vivo tissue ageing, respectively...
Aristotelis Chatziioannou in:Nature Research journals • PubMed • Google ScholarSearch for Ilya Kublanov in:Nature Research journals • PubMed • Google ScholarSearch for Georgios Skretas in:Nature Research ... . Author information AffiliationsInstitute of Biology, Medicinal Chemistry & Biotechnology, National Hellenic Research Foundation, Athens, GreeceDimitra Zarafeta, Evangelia D. Chrysina, Aristotelis
Atherosclerosis is a multifactorial disease involving a lot of genes and proteins recruited throughout its manifestation. The present study aims to exploit bioinformatic tools in order to analyze microarray data of atherosclerotic aortic lesions of ApoE knockout mice, a model widely used in atherosclerosis research. In particular, a dynamic analysis was performed among young and...
Atherosclerosis is a multifactorial disease involving a lot of genes and proteins recruited throughout its manifestation. The present study aims to exploit bioinformatic tools in order to analyze microarray data of atherosclerotic aortic lesions of ApoE knockout mice, a model widely used in atherosclerosis research. In particular, a dynamic analysis was performed among young and...
Atherosclerosis is a multifactorial disease involving a lot of genes and proteins recruited throughout its manifestation. The present study aims to exploit bioinformatic tools in order to analyze microarray data of atherosclerotic aortic lesions of ApoE knockout mice, a model widely used in atherosclerosis research. In particular, a dynamic analysis was performed among young and...
Aristotelis Chatziioannou,2 and Fragiskos Kolisis3 1Neuropsychiatric Research Laboratory, Department of Clinical Medicine, Örebro University, 701 82 Örebro, Sweden 2Metabolic Engineering and Bioinformatics
Aristotelis Chatziioannou,2 and Fragiskos Kolisis3 1Neuropsychiatric Research Laboratory, Department of Clinical Medicine, Örebro University, 701 82 Örebro, Sweden 2Metabolic Engineering and Bioinformatics
Aristotelis Chatziioannou 0 Panagiotis Moulos 0 Fragiskos N Kolisis 0 0 Address: Metabolic Engineering and Bioinformatics Group, Institute of Biological Research and Biotechnology, National
, GreeceAristotelis Chatziioannou, Panagiotis Moulos & Fragiskos N Kolisis AuthorsSearch for Aristotelis Chatziioannou in:PubMed • Google Scholar Search for Panagiotis Moulos in:PubMed • Google Scholar Search for
With the ultimate goal of identifying robust cellulases for industrial biocatalytic conversions, we have isolated and characterized a new thermostable and very halotolerant GH5 cellulase. This new enzyme, termed CelDZ1, was identified by bioinformatic analysis from the genome of a polysaccharide-enrichment culture isolate, initiated from material collected from an Icelandic hot...
Chatziioannou 0 Ilias Maglogiannis 2 Fragiskos N Kolisis 0 0 Metabolic Engineering and Bioinformatics Group, Institute of Biological Research and Biotechnology, National Hellenic Research Foundation , Vassileos
Scholar Search for Ioannis Kanaris in:PubMed • Google Scholar Search for Aristotelis Chatziioannou in:PubMed • Google Scholar Search for Ilias Maglogiannis in:PubMed • Google Scholar Search for Fragiskos ... N Kolisis in:PubMed • Google Scholar Corresponding author Correspondence to Aristotelis Chatziioannou. Additional information Authors' contributions KM co-drafted the manuscript, co-programmed
B-cell chronic lymphocytic leukemia (CLL) is a common type of adult leukemia. It often follows an indolent course and is preceded by monoclonal B-cell lymphocytosis, an asymptomatic condition, however it is not known what causes subjects with this condition to progress to CLL. Hence the discovery of prediagnostic markers has the potential to improve the identification of subjects...
Background Mastic oil from Pistacia lentiscus variation chia, a blend of bioactive terpenes with recognized medicinal properties, has been recently shown to exert anti-tumor growth activity through inhibition of cancer cell proliferation, survival, angiogenesis and inflammatory response. However, no studies have addressed its mechanisms of action at genome-wide gene expression...
