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Role of fibroblast growth factors in bone regeneration

Bone is a metabolically active organ that undergoes continuous remodeling throughout life. However, many complex skeletal defects such as large traumatic bone defects or extensive bone loss after tumor resection may cause failure of bone healing. Effective therapies for these conditions typically employ combinations of cells, scaffolds, and bioactive factors. In this review, we pay ...

Removal of nitrate and sulphate from biologically treated municipal wastewater by electrocoagulation

the form of UGC Research Fellowship (F.4-1/2006 (BSR) 7-70/2007 BSR) to Mr. Arun Kumar Sharma. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0

Molecular and functional characterization of myxobacteria isolated from soil in India

This study reports the isolation of myxobacteria from soil collected from plains in north India. Based on the morphology and 16S rDNA sequence, the isolated myxobacteria were identified as Corallococcus sp., Pyxidicoccus sp., Myxococcus sp., Cystobacter sp. and Archangium sp. The myxobacteria were functionally characterized to assess their ability to produce antibacterial and ...

Artificial intelligence models for predicting the performance of biological wastewater treatment plant in the removal of Kjeldahl Nitrogen from wastewater

The current work demonstrates the support vector machine (SVM) and adaptive neuro-fuzzy inference system (ANFIS) modeling to assess the removal efficiency of Kjeldahl Nitrogen of a full-scale aerobic biological wastewater treatment plant. The influent variables such as pH, chemical oxygen demand, total solids (TS), free ammonia, ammonia nitrogen and Kjeldahl Nitrogen are used as ...

Introducing a novel mushroom from mycophagy community with emphasis on biomedical potency

Mushrooms have been prized by humankind as medicine and culinary wonder since antiquity. Though several species are ethnically valued; many prospective species are still being discovered. One such wild macrofungus has recently been discovered during subsequent field surveys in West Bengal, India which in turn exposed as a traditionally consumed popular myco-food. The collected ...

Metabolomic homeostasis shifts after callus formation and shoot regeneration in tomato

Plants can regenerate from a variety of tissues on culturing in appropriate media. However, the metabolic shifts involved in callus formation and shoot regeneration are largely unknown. The metabolic profiles of callus generated from tomato (Solanum lycopersicum) cotyledons and that of shoot regenerated from callus were compared with the pct1-2 mutant that exhibits enhanced polar ...

Correction: High blood levels of lead in children aged 6-36 months in Kathmandu Valley, Nepal: A cross-sectional study of associated factors

Kumar Aryal Bimala Dhimal Hari Datt Joshi Sajan Puri Achyut Raj Pandey Purushotam Dhakal Arun Kumar Sharma Dhruba Shrestha Ganendra Bhakta Raya Imran Ansari David A. Groneberg Ruth MuÈ ller Ulrich Kuch

Treatment of infected non-unions with segmental defects with a rail fixation system

Orthopaedics, Silchar Medical College , Silchar, Assam 788014 , India 4 Department of Orthopaedics, Kasturba Medical College (Manipal University) , Mangalore, Karnataka 575001 , India Arup Kumar Daolagupu Arun ... Kumar Sipani Satyendra Kumar Das done. For closure of bone gap, acute docking and distraction was done in 18 cases and segmental bone transport in 22 cases. Early mobilization of patient was done along

Zebrafish GDNF and its co-receptor GFRα1 activate the human RET receptor and promote the survival of dopaminergic neurons in vitro

Glial cell line-derived neurotrophic factor (GDNF) is a ligand that activates, through co-receptor GDNF family receptor alpha-1 (GFRα1) and receptor tyrosine kinase “RET”, several signaling pathways crucial in the development and sustainment of multiple neuronal populations. We decided to study whether non-mammalian orthologs of these three proteins have conserved their function: ...

Modulation of oxidative phosphorylation and redox homeostasis in mitochondrial NDUFS4 deficiency via mesenchymal stem cells

Background Disorders of the oxidative phosphorylation (OXPHOS) system represent a large group among the inborn errors of metabolism. The most frequently observed biochemical defect is isolated deficiency of mitochondrial complex I (CI). No effective treatment strategies for CI deficiency are so far available. The purpose of this study was to investigate whether and how mesenchymal ...

Genetic assessment of captive red panda (Ailurus fulgens) population

Red panda (Ailurus fulgens) is threatened across its range by detrimental human activities and rapid habitat changes necessitating captive breeding programs in various zoos globally to save this flagship species from extinction. One of the ultimate aims of ex situ conservation is reintroduction of endangered animals into their natural habitats while maintaining 90 % of the founder ...

High blood levels of lead in children aged 6-36 months in Kathmandu Valley, Nepal: A cross-sectional study of associated factors

Young children are at greatest risk of exposure to lead and its effects. Although lead is one of the most widely used elements with known health hazard, there is little data on the blood lead level (BLL) of children in the Kathmandu Valley. Thus, this study aimed to assess factors associated with high BLL in children who were 6–36 months of age and resided in the Kathmandu Valley. ...

Deciphering the evolutionary affiliations among bacterial strains (Pseudomonas and Frankia sp.) inhabiting same ecological niche using virtual RFLP and simulation-based approaches

, Varanasi 221005 , India 1 & Arun Kumar Mishra To decipher an evolutionary lineage between two different but important bacterial groups, i.e., Pseudomonas strain (c-Proteobacteria) and Frankia strain

Removal of nitrate and sulphate from biologically treated municipal wastewater by electrocoagulation

the form of UGC Research Fellowship (F.4-1/2006 (BSR) 7-70/2007 BSR) to Mr. Arun Kumar Sharma. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0

WAX INDUCER1 (HvWIN1) transcription factor regulates free fatty acid biosynthetic genes to reinforce cuticle to resist Fusarium head blight in barley spikelets

Fusarium head blight (FHB), caused by Fusarium graminearum, is one of the most devastating diseases of wheat and barley. Resistance to FHB is highly complex and quantitative in nature, and is most often classified as resistance to spikelet infection and resistance to spread of pathogen through the rachis. In the present study, a resistant (CI9831) and a susceptible (H106-371) ...

Ocean–atmosphere processes driving Indian summer monsoon biases in CFSv2 hindcasts

This paper analyzes the role of the Indian Ocean (IO) and the atmosphere biases in generating and sustaining large-scale precipitation biases over Central India (CI) during the Indian summer monsoon (ISM) in the climate forecast system version 2 (CFSv2) hindcasts that are produced by initializing the system each month from January 1982 to March 2011. The CFSv2 hindcasts are ...