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Marker-assisted breeding to develop the drought-tolerant version of Sabitri, a popular variety from Nepal

Sabitri is a rice variety grown in a large part of the rainfed areas of Nepal. It was originally developed for irrigated condition; hence, this variety suffers high yield decline under drought. Two QTLs, qDTY 3.2 and qDTY 12.1 , with large effects on grain yield under drought were identified in the Sabitri background in separate QTL mapping studies. The present study reports the ...

Strength Characterization of Cement Stabilized and Fiber Reinforced Clay–Pond Ash Mixes

This paper presents the experimental results obtained from tests conducted on clayey soil specimen stabilized with pond ash (PA) and cement and reinforced with randomly distributed fibers. The amount of PA and cement were varied from 0–50 and 0–6 % respectively by dry weight of the soil. In order to understand the influence of admixture on the strength properties of clay, ...

Interplay between periodic stimulation and GABAergic inhibition in striatal network oscillations

Network oscillations are ubiquitous across many brain regions. In the basal ganglia, oscillations are also present at many levels and a wide range of characteristic frequencies have been reported to occur during both health and disease. The striatum, the main input nucleus of the basal ganglia, receives massive glutamatergic inputs from the cortex and is highly susceptible to ...

Multi-substrate biodegradation of chlorophenols by defined microbial consortium

, National Innovation Foundation-India , Satellite Complex, Jodhpur Tekra, Ahmedabad 380015, Gujarat , India 1 Arvind Kumar 2 & Bhishma P. Patel 3 Environmental Pollution Abatement Lab, Chemical Engineering

Biodegradation of 4-chlorophenol in an airlift inner loop bioreactor with mixed consortium: effect of HRT, loading rate and biogenic substrate

Environmental Pollution Abatement Lab, Chemical Engineering Department, National Institute of Technology , Rourkela, Odisha 769008 , India 1 Arvind Kumar 2 & Bhishma P. Patel In the present work, removal of 4

Association Mapping of Yield and Yield-related Traits Under Reproductive Stage Drought Stress in Rice (Oryza sativa L.)

Background The identification and introgression of major-effect QTLs for grain yield under drought are some of the best and well-proven approaches for improving the drought tolerance of rice varieties. In the present study, we characterized Malaysian rice germplasm for yield and yield-related traits and identified significant trait marker associations by structured association ...

Molecular mapping of the grain iron and zinc concentration, protein content and thousand kernel weight in wheat (Triticum aestivum L.)

Genomic regions responsible for accumulation of grain iron concentration (Fe), grain zinc concentration (Zn), grain protein content (PC) and thousand kernel weight (TKW) were investigated in 286 recombinant inbred lines (RILs) derived from a cross between an old Indian wheat variety WH542 and a synthetic derivative (Triticum dicoccon PI94624/Aegilops squarrosa [409]//BCN). RILs ...

Diversity of bacteria and archaea in the rhizosphere of bioenergy crop Jatropha curcas

Plant-microbial interaction in rhizosphere plays vital role in shaping plant’s growth and ecosystem function. Most of the rhizospheric microbial diversity studies are restricted to bacteria. In natural ecosystem, archaea also constitutes a major component of the microbial population. However, their diversity is less known compared to bacteria. Experiments were carried out to ...

Comparative study between staples and eight plate in the management of coronal plane deformities of the knee in skeletally immature children

figure of eight plate over staples in managing these deformities. Angular deformities around knee; Hemiepiphysiodesis; Staples; Figure of eight plate - & Arvind Kumar Angular deformities around the

Recovery of Dynamics and Function in Spiking Neural Networks with Closed-Loop Control

There is a growing interest in developing novel brain stimulation methods to control disease-related aberrant neural activity and to address basic neuroscience questions. Conventional methods for manipulating brain activity rely on open-loop approaches that usually lead to excessive stimulation and, crucially, do not restore the original computations performed by the network. Thus, ...

Existence and Control of Go/No-Go Decision Transition Threshold in the Striatum

A typical Go/No-Go decision is suggested to be implemented in the brain via the activation of the direct or indirect pathway in the basal ganglia. Medium spiny neurons (MSNs) in the striatum, receiving input from cortex and projecting to the direct and indirect pathways express D1 and D2 type dopamine receptors, respectively. Recently, it has become clear that the two types of MSNs ...

Depth of soil compaction predominantly affects rice yield reduction by reproductive-stage drought at varietal screening sites in Bangladesh, India, and Nepal

Aims Drought is the major constraint to rainfed rice productivity in South Asia, but few reports provide detailed characterization of the soil properties related to drought stress severity in the region. The aim of the study was to provide a compilation of drought breeding network sites and their respective levels of drought stress, and to relate soil parameters with yield ...

Toxicity evaluation of pH dependent stable Achyranthes aspera herbal gold nanoparticles

Alok Tripathi 0 Sarika Kumari 0 Arvind Kumar 0 0 A. Tripathi S. Kumari A. Kumar (&) Faculty of Science, School of Biotechnology, Banaras Hindu University , Varanasi 221005, UP , India Nanoparticles

Pharmacologic efficacy of PU.1 inhibition by heterocyclic dications: a mechanistic analysis

Heterocyclic dications are receiving increasing attention as targeted inhibitors of transcription factors. While many dications act as purely competitive inhibitors, some fail to displace protein efficiently at drug concentrations expected to saturate their DNA target. To achieve a mechanistic understanding of these non-competitive effects, we used a combination of dications, which ...

Marker assisted pyramiding of drought yield QTLs into a popular Malaysian rice cultivar, MR219

Background Three drought yield QTLs, qDTY 2.2 , qDTY 3.1 , and qDTY 12.1 with consistent effect on grain yield under reproductive stage drought stress were pyramided through marker assisted breeding with the objective of improving the grain yield of the elite Malaysian rice cultivar MR219 under reproductive stage drought stress. Foreground selection using QTL specific markers, ...

Reciprocity between Regulatory T Cells and Th17 Cells: Relevance to Polarized Immunity in Leprosy

T cell defect is a common feature in lepromatous or borderline lepromatous leprosy (LL/BL) patients in contrast to tuberculoid or borderline tuberculoid type (TT/BT) patients. Tuberculoid leprosy is characterized by strong Th1-type cell response with localized lesions whereas lepromatous leprosy is hallmarked by its selective Mycobacterium leprae specific T cell anergy leading to ...

Transcriptional profiling of the leaves of near-isogenic rice lines with contrasting drought tolerance at the reproductive stage in response to water deficit

Background Drought tolerance is a complex quantitative trait that involves the coordination of a vast array of genes belonging to different pathways. To identify genes related to the drought-tolerance pathway in rice, we carried out gene-expression profiling of the leaves of near-isogenic lines (NILs) with similar genetic backgrounds and different set of QTLs but contrasting ...

Peptide-Recombinant VP6 Protein Based Enzyme Immunoassay for the Detection of Group A Rotaviruses in Multiple Host Species

We developed a novel enzyme immunoassay for the detection of group A rotavirus (RVA) antigen in fecal samples of multiple host species. The assay is based on the detection of conserved VP6 protein using anti-recombinant VP6 antibodies as capture antibodies and anti-multiple antigenic peptide (identified and constructed from highly immunodominant epitopes within VP6 protein) ...

Pyramiding of drought yield QTLs into a high quality Malaysian rice cultivar MRQ74 improves yield under reproductive stage drought

Research Institute , DAPO Box 7777 Metro Manila , Philippines 1 303, ICRISAT , Patancheru, Hyderabad (TS) , India - 502 324 Arvind Kumar Senior Scientist, Plant Breeder International Rice Research Institute