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Search: authors:"Bashira A. Charles"

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Analyses of genome wide association data, cytokines, and gene expression in African-Americans with benign ethnic neutropenia

. Funding acquisition: Mary Cushman, Charles N. Rotimi, Griffin P. Rodgers. Methodology: Bashira A. Charles, Matthew M. Hsieh, Adebowale A. Adeyemo, Daniel Shriner, Kyung Chin, Kshitij Srivastava, Neil A ... , Griffin P. Rodgers. Writing ± original draft: Bashira A. Charles, Matthew M. Hsieh, Adebowale A. Adeyemo, Daniel Shriner. Writing ± review & editing: Bashira A. Charles, Matthew M. Hsieh, Adebowale A

A genome-wide association study of serum uric acid in African Americans

Background Uric acid is the primary byproduct of purine metabolism. Hyperuricemia is associated with body mass index (BMI), sex, and multiple complex diseases including gout, hypertension (HTN), renal disease, and type 2 diabetes (T2D). Multiple genome-wide association studies (GWAS) in individuals of European ancestry (EA) have reported associations between serum uric acid...