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32 papers found.
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Multiple Cayley-Klein metric learning

: Yanhong Bi. Formal analysis: Yanhong Bi, Bin Fan, Fuchao Wu. Funding acquisition: Bin Fan, Fuchao Wu. Investigation: Yanhong Bi. Methodology: Yanhong Bi, Bin Fan, Fuchao Wu. Resources: Fuchao Wu ... . Software: Yanhong Bi. Supervision: Bin Fan, Fuchao Wu. 13 / 15 Writing ± original draft: Yanhong Bi. Writing ± review & editing: Bin Fan. 14 / 15 1. MacQueen JB . On convergence of k-means and partitions

Pycnogenol® Induces Browning of White Adipose Tissue through the PKA Signaling Pathway in Apolipoprotein E-Deficient Mice

Road, Shenyang 110022, China Correspondence should be addressed to Bin Fan; pj.oc.liamtoh@nibnaf and Jianqiu Gu; moc.361@2111uiqnaijug Received 27 June 2017; Revised 2 October 2017; Accepted 26 October

PD-L1 reverses depigmentation in Pmel-1 vitiligo mice by increasing the abundance of Tregs in the skin

and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai, 200437, ChinaRong Xu, Bin Fan, Jie Chen, Xin Li, Weiwei Mao, Shengyuan Hua & Bin Li AuthorsSearch for Xiao Miao ... in:Nature Research journals • PubMed • Google Scholar Search for Rong Xu in:Nature Research journals • PubMed • Google Scholar Search for Bin Fan in:Nature Research journals • PubMed • Google Scholar

Blockage of NOX2/MAPK/NF-κB Pathway Protects Photoreceptors against Glucose Deprivation-Induced Cell Death

2017; Published 11 September 2017 Academic Editor: Kota V. Ramana Copyright © 2017 Bin Fan et al. This is an open access article distributed under the Creative Commons Attribution License, which ... Ophthalmology. Conflicts of Interest No author has a proprietary interest or a conflict of interest related to this submission. Authors’ Contributions Guang-Yu Li conceived and designed the experiments. Bin Fan

Impact Analysis of Roller System Stability for Four-High Mill Horizontal Vibration

June 2016 Academic Editor: Chao Tao Copyright © 2016 Xiao-bin Fan et al. This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use

Green and efficient dry gel conversion synthesis of SAPO-34 catalyst with plate-like morphology

SAPO-34 catalyst with plate-like morphology was designed and synthesized for the first time, by the dry gel conversion method using cheap triethylamine as a structure-directing agent assisted with seed suspension containing nanosheet-like SAPO-34 seed. The latter played an important role in formation of SAPO-34 (CHA-type) with plate-like morphology. In addition, the yield of the...

Codelivery of dihydroartemisinin and doxorubicin in mannosylated liposomes for drug-resistant colon cancer therapy

Multidrug resistance (MDR) is a major hurdle in cancer chemotherapy and makes the treatment benefits unsustainable. Combination therapy is a commonly used method for overcoming MDR. In this study we investigated the anti-MDR effect of dihydroartemisinin (DHA), a derivative of artemisinin, in combination with doxorubicin (Dox) in drug-resistant human colon tumor HCT8/ADR cells. We...

Iterative Usage of Fixed and Random Effect Models for Powerful and Efficient Genome-Wide Association Studies

False positives in a Genome-Wide Association Study (GWAS) can be effectively controlled by a fixed effect and random effect Mixed Linear Model (MLM) that incorporates population structure and kinship among individuals to adjust association tests on markers; however, the adjustment also compromises true positives. The modified MLM method, Multiple Loci Linear Mixed Model (MLMM...

Pycnogenol Attenuates the Release of Proinflammatory Cytokines and Expression of Perilipin 2 in Lipopolysaccharide-Stimulated Microglia in Part via Inhibition of NF-κB and AP-1 Activation

Over activation of microglia results in the production of proinflammatory agents that have been implicated in various brain diseases. Pycnogenol is a patented extract from French maritime pine bark (Pinus pinaster Aiton) with strong antioxidant and anti-inflammatory potency. The present study investigated whether pycnogenol may be associated with the production of proinflammatory...

Modeling the Relationship between Vibration Features and Condition Parameters Using Relevance Vector Machines for Health Monitoring of Rolling Element Bearings under Varying Operation Conditions

Hu,1,2 Niao-qing Hu,1,2 Bin Fan,1,2 Feng-shou Gu,3 and Xiang-yi Zhang1,2 1Laboratory of Science and Technology on Integrated Logistics Support, National University of Defense Technology, Changsha

A genome-wide scan for signatures of selection in Chinese indigenous and commercial pig breeds

Background Modern breeding and artificial selection play critical roles in pig domestication and shape the genetic variation of different breeds. China has many indigenous pig breeds with various characteristics in morphology and production performance that differ from those of foreign commercial pig breeds. However, the signatures of selection on genes implying for economic...

Japanese encephalitis virus infects porcine kidney epithelial PK15 cells via clathrin- and cholesterol-dependent endocytosis

Background Japanese encephalitis virus (JEV) is a mosquito-borne flavivirus that causes acute viral encephalitis in humans. Pigs are important amplifiers of JEV. The entry mechanism of JEV into porcine cells remains largely unknown. In this study, we present a study of the internalization mechanism of JEV in porcine kidney epithelial PK15 cells. Results We demonstrated that the...

The luminescence properties of Sr3Gd(BO3)3: Tb3+ phosphors under vacuum ultraviolet excitation

Tb3+-activated Sr3Gd(BO3)3 green phosphors were prepared by conventional solid-state reaction. The vacuum ultraviolet (VUV) excitation, photoluminescence (PL) and decay properties of the phosphors in the visible range were investigated. The excitation spectrum showed a strong broad band from 160 to 200 nm with a maximum at 183 nm which was adjacent to the VUV excitation light...

Analysis of Genome-Wide Copy Number Variations in Chinese Indigenous and Western Pig Breeds by 60 K SNP Genotyping Arrays

Copy number variations (CNVs) represent a substantial source of structural variants in mammals and contribute to both normal phenotypic variability and disease susceptibility. Although low-resolution CNV maps are produced in many domestic animals, and several reports have been published about the CNVs of porcine genome, the differences between Chinese and western pigs still...

Photoluminescence and cathodoluminescence properties of a novel CaLaGa3O7:Dy3+ phosphor

A single host white emitting phosphor, CaLaGa3O7:Dy3+, was synthesized by chemical co-precipitation. Field emission scanning electron microscopy, X-ray diffraction, laser particle size analysis, and photoluminescence and cathodoluminescence spectra were used to investigate the structural and optical properties of the phosphor. The phosphor particles were composed of microspheres...

Up-regulation of microglial cathepsin C expression and activity in lipopolysaccharide-induced neuroinflammation

BackgroundCathepsin C (Cat C) functions as a central coordinator for activation of many serine proteases in inflammatory cells. It has been recognized that Cat C is responsible for neutrophil recruitment and production of chemokines and cytokines in many inflammatory diseases. However, Cat C expression and its functional role in the brain under normal conditions or in...

Development of loop-mediated isothermal amplification assay for specific and rapid detection of differential goat Pox virus and Sheep Pox virus

Background Capripox viruses are economically important pathogens in goat and sheep producing areas of the world, with specific focus on goat pox virus (GTPV), sheep pox virus (SPPV) and the Lumpy Skin Disease virus (LSDV). Clinically, sheep pox and goat pox have the same symptoms and cannot be distinguished serologically. This presents a real need for a rapid, inexpensive, and...

Genome-Wide Association Study Identifies Loci for Body Composition and Structural Soundness Traits in Pigs

Background The recent completion of the swine genome sequencing project and development of a high density porcine SNP array has made genome-wide association (GWA) studies feasible in pigs. Methodology/Principal Findings Using Illumina's PorcineSNP60 BeadChip, we performed a pilot GWA study in 820 commercial female pigs phenotyped for backfat, loin muscle area, body conformation...

Tanshinone IIA Inhibits Growth of Keratinocytes through Cell Cycle Arrest and Apoptosis: Underlying Treatment Mechanism of Psoriasis

Wang,1 Bin Fan,1 Lin Geng,1 and Bin Li1 1Department of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine, Shanghai

Astragaloside IV Downregulates β-Catenin in Rat Keratinocytes to Counter LiCl-Induced Inhibition of Proliferation and Migration

 Bin Fan,1 Wen-bin Xu,1 Lin Geng,1 and Bin Li1 1Department of Dermatology, Yueyang Hospital of Integrated Traditional Chinese and Western Medicine, Shanghai University of Traditional Chinese Medicine