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43 papers found.
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Association between rural clinical clerkship and medical students’ intentions to choose rural medical work after graduation: A cross-sectional study in western China

Methodology: Jinlin Liu. Writing ± original draft: Jinlin Liu. Writing ± review & editing: Jinlin Liu, Bin Zhu, Ying Mao. 14 / 16 survey. Asia Pacific Family Medicine. 2015; 14. https://doi.org/10.1186/s12930

Spatial distribution of 12 class B notifiable infectious diseases in China: A retrospective study

Contributions Conceptualization: Bin Zhu, Ying Mao. Data curation: Bin Zhu. Formal analysis: Bin Zhu, Yang Fu. Funding acquisition: Ying Mao. Investigation: Bin Zhu. Methodology: Bin Zhu, Yang Fu ... . Resources: Bin Zhu. Supervision: Yang Fu, Ying Mao. Validation: Jinlin Liu. Visualization: Bin Zhu. 14 / 17 Writing ± original draft: Bin Zhu, Yang Fu. Writing ± review & editing: Bin Zhu, Yang Fu, Jinlin

Identification of two immortalized cell lines, ECV304 and bEnd3, for in vitro permeability studies of blood-brain barrier

, Bin Zhu. Methodology: Shu Yang, Shenghui Mei. Supervision: Anchen Guo, Zhigang Zhao. Writing ± original draft: Shu Yang, Hong Jin. Writing ± review & editing: Xu Cui, Anchen Guo. 8 / 10 10

Reconstruct the proximal radius with iliac graft and elastic intramedullary nail fixation after tumor resection

Background This study aims to introduce a novel technique in treating benign bone tumors of the proximal radius by elastic intramedullary nail fixation and iliac graft after tumor resection. Method In this retrospective case series, the treatment outcomes of 17 patients with benign bone tumor involving the proximal radius were reported from January 2010 to August 2014. All the...

Cytological and morphological analysis of hybrids between Brassicoraphanus, and Brassica napus for introgression of clubroot resistant trait into Brassica napus L

Interspecific hybridization is a powerful tool for improvement of crop species, it has the potential to broaden the genetic base and create new plant forms for breeding programs. Synthetic allopolyploid is a widely-used model for the study of genetic recombination and fixed heterosis in Brassica. In Brassica napus breeding, identification and introgression of new sources of...

Composite cell sheet for periodontal regeneration: crosstalk between different types of MSCs in cell sheet facilitates complex periodontal-like tissue regeneration

Background Tissue-engineering strategies based on mesenchymal stem cells (MSCs) and cell sheets have been widely used for periodontal tissue regeneration. However, given the complexity in periodontal structure, the regeneration methods using a single species of MSC could not fulfill the requirement for periodontal regeneration. Methods We researched the interaction between the...

The long-term outcomes following the use of inactivated autograft in the treatment of primary malignant musculoskeletal tumor

Bin Zhu 0 Kai Fu 0 Qingcheng Yang 0 0 Jielai Yang and Bin Zhu are co-first authors. Department of Orthopedics, Shanghai Jiao Tong University Affiliated Sixth People's Hospital , Shanghai 200233 , China

Towards the natural gauge mediation

The sweet spot supersymmetry (SUSY) solves the μ/B μ problem in the Minimal Supersymmetric Standard Model (MSSM) with gauge mediated SUSY breaking (GMSB) via the generalized Giudice-Masiero (GM) mechanism where only the μ-term and soft Higgs masses are generated at the unification scale of the Grand Unified Theory (GUT) due to the approximate PQ symmetry. Because all the other...

Inhibition of oleandrin on the proliferation show and invasion of osteosarcoma cells in vitro by suppressing Wnt/β-catenin signaling pathway

Background Osteosarcoma (OS) is a high-grade bone sarcoma with early metastasis potential, and the clinical chemotherapy drugs that are currently used for its treatment have some limitations. Recently, several studies have reported the selective antitumor effect of oleandrin on various tumor cells. In this study, we aimed to evaluate the effects and underlying mechanisms of...

Syn5 RNA polymerase synthesizes precise run-off RNA products

Bin Zhu 0 Stanley Tabor 0 Charles C. Richardson 0 0 Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School , 240 Longwood Avenue, Boston, Massachusetts 02115, USA The

Synthesis of 2′-Fluoro RNA by Syn5 RNA polymerase

The substitution of 2′-fluoro for 2′-hydroxyl moieties in RNA substantially improves the stability of RNA. RNA stability is a major issue in RNA research and applications involving RNA. We report that the RNA polymerase from the marine cyanophage Syn5 has an intrinsic low discrimination against the incorporation of 2′-fluoro dNMPs during transcription elongation. The presence of...

Evaluation of diagnostic criteria for IgG4-related tubulointerstitial nephritis

Background IgG4-TIN is the most common pattern of renal involvement in IgG4-related disease. There are several proposed diagnostic criteria of IgG4-TIN recently. Two of them proposed by the Mayo Clinic and JSN are predominant. However, histopathological criteria of the number of IgG4+ plasma cells and several histological features are still under discussion due to low amount of...

Generation and Characterization of Mice Expressing a Conditional Allele of the Interleukin-1 Receptor Type 1

The cytokines IL-1α and IL-1β exert powerful pro-inflammatory actions throughout the body, mediated primarily by the intracellular signaling capacity of the interleukin-1 receptor (IL-1R1). Although Il1r1 knockout mice have been informative with respect to a requirement for IL-1R1 signaling in inflammatory events, the constitutive nature of gene elimination has limited their...

Focus point supersymmetry in extended gauge mediation

We propose a small extension of the minimal gauge mediation through the combination of extended gauge mediation and conformal sequestering. We show that the focus point supersymmetry can be realized naturally, and the fine tuning is significantly reduced compared to the minimal gauge mediation and extended gauge mediation without focus point. The Higgs boson mass is around 125...

Investigation the Possibility of Using Peptides with a Helical Repeating Pattern of Hydro-Phobic and Hydrophilic Residues to Inhibit IL-10

Blockade of IL-10 signalling clears chronic viral and bacterial infections. Immunization together with blockade of IL-10 signalling or relatively low level of IL-10 further enhances viral and bacterial clearance. IL-10 functions through binding to interleukin 10 receptor (IL-10R). Here we showed that peptides P1 and P2 with the hydrophobic and hydrophilic pattern of the IL10R...

Cerebral Glioma Grading Using Bayesian Network with Features Extracted from Multiple Modalities of Magnetic Resonance Imaging

Many modalities of magnetic resonance imaging (MRI) have been confirmed to be of great diagnostic value in glioma grading. Contrast enhanced T1-weighted imaging allows the recognition of blood-brain barrier breakdown. Perfusion weighted imaging and MR spectroscopic imaging enable the quantitative measurement of perfusion parameters and metabolic alterations respectively. These...

Identification of Differentially Expressed Genes in the Pheromone Glands of Mated and Virgin Bombyx mori by Digital Gene Expression Profiling

Background Mating decreases female receptivity and terminates sex pheromone production in moths. Although significant progress has been made in elucidating the mating-regulated inactivation of pheromone biosynthesis-activating neuropeptide (PBAN) secretion, little is known about the mating induced gene expression profiles in pheromone glands (PGs). In this study, the associated...