Lung cancer remains a major cause of cancer-related lethality because of high incidence and recurrence in spite of significant advances in staging and therapies. Recent data indicates that stem cells situated throughout the airways may initiate cancer formation. These putative stem cells maintain protumorigenic characteristics including high proliferative capacity, multipotent...
Lung cancer remains a major cause of cancer-related lethality because of high incidence and recurrence in spite of significant advances in staging and therapies. Recent data indicates that stem cells situated throughout the airways may initiate cancer formation. These putative stem cells maintain protumorigenic characteristics including high proliferative capacity, multipotent...
Lung cancer remains a major cause of cancer-related lethality because of high incidence and recurrence in spite of significant advances in staging and therapies. Recent data indicates that stem cells situated throughout the airways may initiate cancer formation. These putative stem cells maintain protumorigenic characteristics including high proliferative capacity, multipotent...
Elizabeth A. David 1 M. Blair Marshall 0 1 0 Division of Thoracic Surgery, Department of General Surgery, Georgetown University Hospital , 4th Floor PHC Building, 3800 Reservoir Rd, Washington, DC
Elizabeth A. David 1 M. Blair Marshall 0 0 Division of Thoracic Surgery, Department of General Surgery, Georgetown University Hospital , 4th Floor PHC Building, 3800 Reservoir Rd, Washington, DC
M. Blair Marshall 0 Thais Oliveira 0 0 Division of Thoracic Surgery, Department of Surgery, Georgetown University Medical Center , 4 PHC, 3800 Reservoir Rd. NW, Washington, DC 20007, USA We report a
Due to the limited exposure, technical challenges, and postoperative pain of thoracic spine surgery, open thoracotomy and video-assisted thoracic surgery (VATS) are associated with significant morbidity and mortality. The modified French-window thoracotomy approach with the aid of a thoracoscope is a useful technique for approaching diseases of the anterior spinal. This approach...
TGF-β/Smads regulate a wide variety of biological responses through transcriptional regulation of target genes. ELF, a β-spectrin, plays a key role in the transmission of TGF-β-mediated transcriptional response through Smads. ELF was originally identified as a key protein involved in endodermal stem/progenitor cells committed to foregut lineage. Also, as a major dynamic adaptor...
