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Analyzing Breathing Signals and Swallow Sequence Locality for Solid Food Intake Monitoring

Self-reported questionnaires are widely used by researchers for analyzing the dietary behavior of overweight and obese individuals. It has been established that questionnaire-based data collection often suffers from high errors due to its reporting subjectivity. Automatic swallow detection, as an alternative to questionnaires, is proposed in this paper to avoid such subjectivity. ...

Management of screwdriver-induced penetrating brain injury: a case report

Background Penetrating brain injury (PBI) can be caused by several objects ranging from knives to chopsticks. However, an assault with long and electric screwdriver is a peculiar accident and is relatively rare. Because of its rarity, the treatments of such injury are complex and nonstandardized. Case presentation We presented a case of a 54-year-old female who was stabbed with a ...

The Nup98 Homolog APIP12 Targeted by the Effector AvrPiz-t is Involved in Rice Basal Resistance Against Magnaporthe oryzae

Background The effector AvrPiz-t of Magnaporthe oryzae has virulence function in rice. However, the mechanism underlying its virulence in host is not fully understood. Results In this study, we analyzed the function of AvrPiz-t interacting protein 12 (APIP12) in rice immunity. APIP12 significantly bound to AvrPiz-t and APIP6 in its middle portion and N-terminus, respectively, in ...

The platelet-derived growth factor receptor/STAT3 signaling pathway regulates the phenotypic transition of corpus cavernosum smooth muscle in rats

Erectile dysfunction (ED) is a common clinical disease that is difficult to treat. We previously found that hypoxia modulates the phenotype of primary corpus cavernosum smooth muscle cells (CCSMCs) in rats, but the underlying molecular mechanism is still unknown. Platelet-derived growth factor receptor (PDGFR)-related signaling pathways are correlated with cell phenotypic ...

A fat body-derived apical extracellular matrix enzyme is transported to the tracheal lumen and is required for tube morphogenesis in Drosophila

Bo Dong Guangxia Miao Shigeo Hayashi () The apical extracellular matrix plays a central role in epithelial tube morphogenesis. In the Drosophila tracheal system, Serpentine (Serp), a secreted chitin

Persistently high prevalence of primary resistance and multidrug resistance of tuberculosis in Heilongjiang Province, China

Background The spread of multidrug-resistant tuberculosis (MDR-TB) Mycobacterium tuberculosis (M. tuberculosis) strains has been a big challenge to the TB control and prevention in China. Knowledge about patterns of drug resistance in TB high-burden areas of China is crucial to develop appropriate control strategies. We conducted a comprehensive investigation of the resistance ...

Assembly and positioning of actomyosin rings by contractility and planar cell polarity

Jiang ZR2015DM003 and 31572352 Bo Dong The funders had no role in study design, data collection and interpretation, or the decision to submit the work for publication. Author contributions IMS, DJ

ACE2 activity was increased in atherosclerotic plaque by losartan: Possible relation to anti-atherosclerosis

Introduction: Angiotensin-converting enzyme 2 (ACE2) is a new member of the renin–angiotensin system (RAS) and it has been proposed that ACE2 is a potential therapeutic target for the control of cardiovascular disease. The effect of losartan on the ACE2 activity in atherosclerosis was studied.

An Equatorial Contractile Mechanism Drives Cell Elongation but not Cell Division

A cytokinesis-like contractile mechanism is co-opted in a different developmental scenario to achieve cell elongation instead of cell division in Ciona intestinalis.

Comparative transcriptome profiling of a desert evergreen shrub, Ammopiptanthus mongolicus, in response to drought and cold stresses

Background The molecular mechanisms involved in plant tolerance to either drought or cold have been extensively studied in many plant species. However, few studies have focused on their comparisons especially using non-model plants with strong tolerance to both stresses. Ammopiptanthus mongolicus (Maxim. ex Kom.) Cheng f. is the only evergreen broadleaf shrub grown in the central ...

Crosstalk between SNF1 Pathway and the Peroxisome-Mediated Lipid Metabolism in Magnaporthe oryzae

The SNF1/AMPK pathway has a central role in response to nutrient stress in yeast and mammals. Previous studies on SNF1 function in phytopathogenic fungi mostly focused on the catalytic subunit Snf1 and its contribution to the derepression of cell wall degrading enzymes (CWDEs). However, the MoSnf1 in Magnaporthe oryzae was reported not to be involved in CWDEs regulation. The ...

miR-212 promotes pancreatic cancer cell growth and invasion by targeting the hedgehog signaling pathway receptor patched-1

Background microRNAs (miRNAs) are a class of small non-coding RNAs that play important roles in carcinogenesis. In the present study, we investigated the effect of miR-212 on pancreatic ductal adenocarcinoma (PDAC) and its target protein. Methods Quantitative real-time PCR(qRT-PCR) was performed to detect the expression of miR-212 in PDAC tissues and pancreatic cancer cell lines. ...

Distinct cytoskeleton populations and extensive crosstalk control Ciona notochord tubulogenesis

Bo Dong 0 Wei Deng 0 Di Jiang () 0 0 Sars International Centre for Marine Molecular Biology, University of Bergen , Thormhlensgate 55, N-5008 Bergen , Norway SUMMARY Cell elongation is a fundamental

Predicting Housekeeping Genes Based on Fourier Analysis

Housekeeping genes (HKGs) generally have fundamental functions in basic biochemical processes in organisms, and usually have relatively steady expression levels across various tissues. They play an important role in the normalization of microarray technology. Using Fourier analysis we transformed gene expression time-series from a Hela cell cycle gene expression dataset into ...

Broad reprocessed Balmer emission from warped accretion discs

Sheng-Miao Wu 0 Ting-Gui Wang 0 Xiao-Bo Dong 0 0 Centre for Astrophysics, University of Science and Technology of China , Hefei 230026 , China A B S T R A C T Double-peaked broad emission lines in

Type 1 active galactic nucleus fraction in the SDSS/FIRST survey

In the unification scheme, narrow-lined (type 2) active galactic nuclei (AGNs) are intrinsically similar to broad-lined (type 1) AGNs, with the exception that the line of sight to the broad emission-line region and accretion disc is blocked by a dusty torus. The fraction of type 1 AGNs measures the average covering factor of the torus. In this paper, we explore the dependence of ...

The Caenorhabditis elegans intermediate-size transcriptome shows high degree of stage-specific expression

Earlier studies have revealed a substantial amount of transcriptional activity occurring outside annotated protein-coding genes of the Caenorhabditis elegans genome. One important fraction of this transcriptional activity relates to intermediate-size (70–500 nt) transcripts (is-ncRNAs) of mostly unknown function. Profiling the expression of this segment of the transcriptome on a ...