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217 papers found.
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Visualizing the spatiotemporal map of Rac activation in bovine aortic endothelial cells under laminar and disturbed flows

, Xiaoling Liao, Bo Liu. Funding acquisition: Xiaoling Liao, Bo Liu. Methodology: Cheng Xiang, Bo Liu. Writing ± original draft: Shuai Shao, Cheng Xiang, Kairong Qin, Aziz ur Rehman Aziz, Bo Liu. Writing ... ± review & editing: Shuai Shao, Bo Liu. 12 / 14 13 / 14 1. Barakat A , Lieu D. Differential responsiveness of vascular endothelial cells to different types of fluid mechanical shear stress . Cell

The Coupling Effects of Surface Plasmon Polaritons and Magnetic Dipole Resonances in Metamaterials

We numerically investigate the coupling effects of surface plasmon polaritons (SPPs) and magnetic dipole (MD) resonances in metamaterials, which are composed of an Ag nanodisk array and a SiO2 spacer on an Ag substrate. The periodicity of the Ag nanodisk array leads to the excitation of SPPs at the surface of the Ag substrate. The near-field plasmon interactions between individual ...

Quantifying the Effect of Salinity Stratification on Phytoplankton Density Patterns in Estuaries

To quantify the effect of salinity stratification on phytoplankton density (denoted as P) patterns, experiments were conducted with an idealised model that couples physical and biological processes. Results show that the idealised model is capable of capturing the main features of observed P patterns in the Columbia River estuary during the spring season: during weak ...

Control scheme of hexagonal modular multilevel direct converter for offshore wind power integration via fractional frequency transmission system

fractional frequency transmission system, flexible alternative current transmission systems (FACTS) and power quality of the grid. Bo LIU received the B.S. degree in electrical engineering and its automation

Fitting power-laws in empirical data with estimators that work for all exponents

Most standard methods based on maximum likelihood (ML) estimates of power-law exponents can only be reliably used to identify exponents smaller than minus one. The argument that power laws are otherwise not normalizable, depends on the underlying sample space the data is drawn from, and is true only for sample spaces that are unbounded from above. Power-laws obtained from bounded ...

Key Technologies of the Independent and Innovative Communications-Based Train Control Systems in China

In the past 10 years, the independent and innovative communications-based train control system has experienced breakthroughs in key technologies by conducting pilot experiments, field tests, and demonstration projects. For the first time, the design theories and technical aspects of moving block systems, which cover the entire life cycle of fail-safe systems, are set up. The models ...

Investigating the Co-Adsorption Behavior of Nucleic-Acid Base (Thymine and Cytosine) and Melamine at Liquid/Solid Interface

0 Bo Liu 0 0 Institute of Photo-biophysics, School of Physics and Electronics, Henan University , Kaifeng 475004 , People's Republic of China The co-adsorption behavior of nucleic-acid base (thymine

Disseminated mucormycosis (DM) after pneumonectomy: a case report

Background Mucormycosis is a kind of rare opportunistic fungal disease and the incidence of which has gradually increased. Disseminated mucormycosis (DM) is a life-threatening infection that mostly occurs in immunocompromised patients. The lung and brain are usually involved in disseminated mucormycosis, and other sites are scare. We report the first case of disseminated ...

Serum miR-95-3p is a diagnostic and prognostic marker for osteosarcoma

It has been demonstrated that microRNAs (miRNAs or miRs) can act as prognostic and diagnostic markers, and potential therapeutic targets. miR-95-3p has been reported to be downregulated in osteosarcoma tissues, but its potential as a serum biomarker has not been assessed in human osteosarcoma. The purpose of the present study was to examine the expression levels of miR-95-3p in ...

Effect of active vitamin D3 on VEGF-induced ADAM33 expression and proliferation in human airway smooth muscle cells: implications for asthma treatment

Background Asthma is a chronic respiratory disease characterized by reversible airway obstruction with persistent airway inflammation and airway remodeling, which is associated with increased airway smooth muscle (ASM) mass. Vascular endothelial growth factor (VEGF) has been implicated in inflammatory and airway blood vessel remodeling in asthma. Recent evidence indicates that a ...

Diffusion Tensor Imaging for Evaluating Biliary Atresia in Infants and Neonates

Background Preliminary studies have shown that diffusion tensor imaging (DTI) is helpful in evaluating liver disorders. However, there is no published literature on the use of DTI in the diagnosis of biliary atresia (BA). This study aimed to investigate the diagnostic value of the liver average apparent diffusion coefficient (ADC) and fractional anisotropy (FA) measured using DTI ...

Impact of Conditional miRNA126 Overexpression on Apoptosis-Resistant Endothelial Cell Production

The activation of endothelial cells is essential to repair damage caused by atherosclerosis via endothelial cell proliferation and migration. Overexpression of VEGF (vascular endothelial growth factor) and the downstream gene, B-cell lymphoma-2 (BCL-2) could result in apoptosis-resistant endothelial cells, which are responsible for aggravated hyperplasia and instable plaques ...

Investigation of Inclusion Complex of Patchouli Alcohol with β-Cyclodextrin

Liu 0 1 0 The Second Affiliated Hospital of Guangzhou University of Chinese Medicine, Guangdong Provincial Academy of Chinese Medical Sciences , Guangzhou , China , 2 Guangdong Pharmaceutical

Comparisons of volumetric modulated arc therapy (VMAT) quality assurance (QA) systems: sensitivity analysis to machine errors

Background In volumetric modulated arc therapy (VMAT), gantry angles, dose rate and the MLC positions vary with the radiation delivery. The quality assurance (QA) system should be able to catch the planning and machine errors. The aim of this study was to investigate the sensitivity of three VMAT QA systems to machine errors. Methods Several types of potential linac machine errors ...

Expression of multiple Bacillus subtilis genes is controlled by decay of slrA mRNA from Rho-dependent 3′ ends

Timely turnover of RNA is an important element in the control of bacterial gene expression, but relatively few specific targets of RNA turnover regulation are known. Deletion of the Bacillus subtilis pnpA gene, encoding the major 3′ exonuclease turnover enzyme, polynucleotide phosphorylase (PNPase), was shown previously to cause a motility defect correlated with a reduced level of ...

Structural transformation induced by locked nucleic acid or 2′–O-methyl nucleic acid site-specific modifications on thrombin binding aptamer

Background Locked nucleic acid (LNA) and 2'–O-methyl nucleic acid (OMeNA) are two of the most extensively studied nucleotide derivatives in the last decades. However, how they affect DNA quadruplex structures remains largely unknown. To explore their possible biological affinities for quadruplexes, we investigated how LNA- or OMeNA-substitutions affect G-quadruplex structure ...

Classical swine fever virus replicated poorly in cells from MxA transgenic pigs

Background In addition to their value as livestock, pigs are susceptible to classical swine fever virus (CSFV) and can serve as reservoirs for CSFV, allowing it to develop into an epizootic. CSFV, a pestivirus of the Flaviviridae family, has a single-stranded RNA genome. Recent research has indicated that the human MxA protein inhibits the life cycles of certain RNA viruses, such ...

Characterization of the Sweet Taste Receptor Tas1r2 from an Old World Monkey Species Rhesus Monkey and Species-Dependent Activation of the Monomeric Receptor by an Intense Sweetener Perillartine

Sweet state is a basic physiological sensation of humans and other mammals which is mediated by the broadly acting sweet taste receptor-the heterodimer of Tas1r2 (taste receptor type 1 member 2) and Tas1r3 (taste receptor type 1 member 3). Various sweeteners interact with either Tas1r2 or Tas1r3 and then activate the receptor. In this study, we cloned, expressed and functionally ...

IGSA: Individual Gene Sets Analysis, including Enrichment and Clustering

Analysis of gene sets has been widely applied in various high-throughput biological studies. One weakness in the traditional methods is that they neglect the heterogeneity of genes expressions in samples which may lead to the omission of some specific and important gene sets. It is also difficult for them to reflect the severities of disease and provide expression profiles of gene ...