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Trends in autumn rain of West China from 1961 to 2014

Autumn rain of West China is a typical climate phenomenon, which is characterized by continuous rainy days and large rainfall amounts and exerts profound impacts on the economic society. Based on daily precipitation data from 524 observation stations for the period of 1961–2014, this article comprehensively examined secular changes in autumn rain of West China, including its...

Research and Design No Light Spot in Front Located Hysteroscopy

This paper first introduces the recent development of the popular hysteroscopy, the international minimally invasive diagnosis instrument, and then analyzes the lighting and video of hysteroscopy. According to high energy consumption of common hysteroscopy, front located hysteroscopy system is put forward. The no light spot principles, the lens structure, the manufacture process...

Fabrication and Super-Antibacterial Property of Nanosilver/Sericin/Poly(ethylene oxide) Nanofibers through Electrospinning-Combined Postdeposition Method

/SS/PEO nanofiber mats. Competing Interests The authors declare that there are no competing interests. Authors’ Contributions Jia Li and Bo-Xiang Wang contributed equally to this work. Acknowledgments

Differential MR Delayed Enhancement Patterns of Chronic Myocardial Infarction between Extracellular and Intravascular Contrast Media

Objectives Because the distribution volume and mechanism of extracellular and intravascular MR contrast media differ considerably, the enhancement pattern of chronic myocardial infarction with extracellular or intravascular media might also be different. This study aims to investigate the differences in MR enhancement patterns of chronic myocardial infarction between...

Cardiac papillary fibroelastoma: a retrospect of four cases

Objective We have reviewed the medical histories of 4 patients who underwent operations between November 2004 and February 2011 at Changhai Hospital for cardiac papillary fibroelastoma. Methods Diagnosis was demonstrably suggested by echocardiography. Tumor locations were mitral valve (1), left atrium (1), and aortic valve (2). Indications for operation were previous...

Pathological Mechanism for Delayed Hyperenhancement of Chronic Scarred Myocardium in Contrast Agent Enhanced Magnetic Resonance Imaging

Objectives To evaluate possible mechanism for delayed hyperenhancement of scarred myocardium by investigating the relationship of contrast agent (CA) first pass and delayed enhancement patterns with histopathological changes. Materials and Methods Eighteen pigs underwent 4 weeks ligation of 1 or 2 diagonal coronary arteries to induce chronic infarction. The hearts were then...

Signaling pathways in the development of infantile hemangioma

Infantile hemangioma (IH), which is the most common tumor in infants, is a benign vascular neoplasm resulting from the abnormal proliferation of endothelial cells and pericytes. For nearly a century, researchers have noted that IH exhibits diverse and often dramatic clinical behaviors. On the one hand, most lesions pose no threat or potential for complication and resolve...

A Novel CDX2 Isoform Regulates Alternative Splicing

Gene expression is a dynamic and coordinated process coupling transcription with pre-mRNA processing. This regulation enables tissue-specific transcription factors to induce expression of specific transcripts that are subsequently amplified by alternative splicing allowing for increased proteome complexity and functional diversity. The intestine-specific transcription factor CDX2...

Fetus in fetu: two case reports and literature review

Background Fetus in fetu is a rare congenital anomaly and is defined as a monozygotic twin incorporated into the abdomen of its sibling during development. Fetus in fetu is often overlooked in the differential diagnosis of an abdominal mass. Unlike teratomas, fetus in fetu is a benign disorder. Case presentation We describe the clinical characteristics of two patients, a thirty...

LOC401317, a p53-Regulated Long Non-Coding RNA, Inhibits Cell Proliferation and Induces Apoptosis in the Nasopharyngeal Carcinoma Cell Line HNE2

Recent studies have revealed that long non-coding RNAs participate in all steps of cancer initiation and progression by regulating protein-coding genes at the epigenetic, transcriptional, and post-transcriptional levels. Long non-coding RNAs are in turn regulated by other genes, forming a complex regulatory network. The regulation networks between the p53 tumor suppressor and...

Assessment of three techniques for delivering stem cells to the heart using PET and MR imaging

Background Stem cell therapy has a promising potential for the curing of various degenerative diseases, including congestive heart failure (CHF). In this study, we determined the efficacy of different delivery methods for stem cell administration to the heart for the treatment of CHF. Both positron emission tomography (PET) and magnetic resonance imaging (MRI) were utilized to...

Genome-Wide Association Analysis with Gray Matter Volume as a Quantitative Phenotype in First-Episode Treatment-Naïve Patients with Schizophrenia

Reduced Gray matter (GM) volume is a core feature of schizophrenia. Mapping genes that is associated with the heritable disease-related phenotypes may be conducive to elucidate the pathogenesis of schizophrenia. This study aims to identify the common genetic variants that underlie the deficits of GM volume in schizophrenia. High-resolution T1 images and whole genome genotyping...

Butorphanol prevents morphine-induced pruritus without increasing pain and other side effects: a systematic review of randomized controlled trials

this work. Xue-Yin Shi is the primary corresponding author. - Author contributions Bo-Xiang Du, Zhe-Ming Song, Zui Zou, and Hao Zhang helped design the study. Bo-Xiang Du, Zhe-Ming Song, Zui Zou, and ... Xue-Yin Shi helped conduct the study. Bo-Xiang Du, Zhe-Ming Song, Zui Zou, and Feng-Ying Xu helped analyze the data and write the manuscript. Bo-Xiang Du, Zhe-Ming Song, Zui Zou, Kai Wang, Hao Zhang

Regulation network and expression profiles of Epstein-Barr virus-encoded microRNAs and their potential target host genes in nasopharyngeal carcinomas

Epstein-Barr virus (EBV) is associated with nasopharyngeal carcinoma (NPC) tumorigenesis. However, the mechanism(s) connecting EBV infection and NPC remain unclear. Recently, a new class of EBV microRNAs (miRNAs) has been described. To determine how EBV miRNAs control the expression of host genes, and to understand their potential role in NPC tumorigenesis, we profiled the...

LPLUNC1 Inhibits Nasopharyngeal Carcinoma Cell Growth via Down-Regulation of the MAP Kinase and Cyclin D1/E2F Pathways

Zhaojian Gong Jian Ma Ming Zhou Juanjuan Xiang Shuping Peng Bo Xiang Hao Deng Yunbo Yang Yong Li Wei Xiong Zhaoyang Zeng Guiyuan Li Srikumar P. Chellappan, H. Lee Moffitt Cancer Center & Research Institute

SPLUNC1 Regulates Cell Progression and Apoptosis through the miR-141-PTEN/p27 Pathway, but Is Hindered by LMP1

Chen Xiaofang Guo Houde Zhou Wenling Zhang Zhaoyang Zeng Qianjin Liao Xiayu Li Bo Xiang Jianbo Yang Jian Ma Ming Zhou Shuping Peng Juanjuan Xiang Xiaoling Li Colvin Wanshura LE Wei Xiong James B

Cortical Surface Area Correlates with STON2 Gene Ser307Pro Polymorphism in First-Episode Treatment-Naïve Patients with Schizophrenia

Background Evidence shows that STON2 gene is associated with synaptic function and schizophrenia. This study aims to explore the relationship between two functional polymorphisms (Ser307Pro and Ala851Ser) of STON2 gene and the cortical surface area in first-episode treatment-naïve patients with schizophrenia and healthy controls. Methodology/Principal Findings Magnetic resonance...