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The life of [PSI]

The AAA+ disaggregase Hsp104 is essential for the maintenance and inheritance of nearly all known prions of the yeast Saccharomyces cerevisiae. Uniquely for [PSI +], the prion form of the Sup35 protein, there seem to be two activities, involving differing co-chaperones, by which Hsp104 affects the inheritance of [PSI +], the prion form of the Sup35 protein. Each pathway is also ...

Turning the Tide: The Future of HIV Criminalization after Rhoades v. State and Legislative Reform in Iowa

:// Brian Cox - Article 2 Copyright 2016 by Northwestern University Pritzker School of Law Northwestern Journal of Law and Social Policy Brian Cox I. INTRODUCTION In the decades

A comparison of trends in melanoma mortality in New Zealand and Australia: the two countries with the highest melanoma incidence and mortality in the world

Background New Zealand and Australia have the highest incidence and mortality rates from cutaneous melanoma in the world. The predominantly fair-skinned New Zealanders and Australians both enjoy sun, tanned skin and the outdoors, and differences in these activities among generations have been important determinants of trends in melanoma mortality.We examined whether New Zealand ...

Individual risk of cutaneous melanoma in New Zealand: developing a clinical prediction aid

Background New Zealand and Australia have the highest melanoma incidence rates worldwide. In New Zealand, both the incidence and thickness have been increasing. Clinical decisions require accurate risk prediction but a simple list of genetic, phenotypic and behavioural risk factors is inadequate to estimate individual risk as the risk factors for melanoma have complex interactions. ...

Manifest causality in quantum field theory with sources and detectors

We introduce a way to compute scattering amplitudes in quantum field theory including the effects of particle production and detection. Our amplitudes are manifestly causal, by which we mean that the source and detector are always linked by a connected chain of retarded propagators. We show how these amplitudes can be derived from a path integral, using the Schwinger-Keldysh ...

Building bridges from 'omics' to cell biology

A report from the Keystone Symposium on Molecular and Cellular Biology, 'Omics Meets Cell Biology', Breckenridge, Colorado, 25-30 January, 2009.

School Milk and Risk of Colorectal Cancer: A National Case-Control Study

Brian Cox ) 0 Mary J. Sneyd 0 0 University of Otago Medical School , P.O. Box 913, Dunedin 9054 , New Zealand ( American Journal of Epidemiology The Author 2011. Published by Oxford University ... , Dunedin, New Zealand (Brian Cox, Mary J. Sneyd). This work was supported by the Genesis Oncology Trust, the Deans Bequest Funds of the Dunedin School of Medicine, the Gisborne-East Coast Cancer Research

Circulation Autumn: Some Thoughts on Forty Fulfilment Years

Circulation Autumn: Some Thou Fulfi lment Years Brian Cox Elsevier Science Ltd.